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STAT5A

Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. STAT5A orthologs have been identified in several placentals for which complete genome data are available.

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Aliases
STAT5A, MGF, STAT5, signal transducer and activator of transcription 5A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y1U
Band
17q21.2 · 11 D|11 63.77 cM
Bgee
granulocyte · monocyte · left adrenal cortex · right adrenal cortex · subcutaneous adipose tissue
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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STAT5A

Nodes41
Edges40
Triples146
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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STAT5A

Top relations

Gene ontology · 43
STAT5A → 2-oxoglutarate metabolic process, allantoin metabolic process, citrate metabolic process, creatine metabolic process, creatinine metabolic process, cytokine-mediated signaling pathway, cytoplasm, cytosol, defense response, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, fatty acid metabolic process, growth hormone receptor signaling pathway via JAK-STAT, interleukin-15-mediated signaling pathway, interleukin-2-mediated signaling pathway, interleukin-7-mediated signaling pathway, interleukin-9-mediated signaling pathway, isoleucine metabolic process
Bgee · 19
STAT5A → appendix, blood, brown adipose tissue, choroid plexus of fourth ventricle, cumulus cell, gastric mucosa, granulocyte, Ileal epithelium, lactiferous gland, left adrenal cortex, lymph node, monocyte, parotid gland, perirhinal cortex, right adrenal cortex, seminal vesicula, subcutaneous adipose tissue, tendon of biceps brachii, thymus
RNA expression pattern · 19
STAT5A → appendix, blood, brown adipose tissue, choroid plexus of fourth ventricle, cumulus cell, gastric mucosa, granulocyte, Ileal epithelium, lactiferous gland, left adrenal cortex, lymph node, monocyte, parotid gland, perirhinal cortex, right adrenal cortex, seminal vesicula, subcutaneous adipose tissue, tendon of biceps brachii, thymus
related to Structure · 10
STAT5A → C-terminal, DNA, GAS, Homology, It, Linker, N-Terminal, STAT, STAT5b, The
related to Interactions · 7
STAT5A → CBX5, CRKL, Epidermal, ERBB4, Erythropoietin, Janus, MAPK1NMI
related to As a drug target · 6
STAT5A → Because, Inhibition, JAK2-STAT5, So, STAT5a/b, Therapy
related to Breast cancer · 6
STAT5A → Because, High STAT5a, In, It, STAT5b, Studies
related to Clinical signficance · 5
STAT5A → Because, Many, STAT5b, Unphosphorylated, Until
related to Prostate cancer · 3
STAT5A → JAK2-STAT5a/b, Prolactin, Stat5a/b
Band · 2
STAT5A → 11 D|11 63.77 cM, 17q21.2

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Important terminology

cancer gene bp human prostate protein cell chr band shown transcription breast expression growth function chromosome 17 activity stat specific

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
STAT5AAliasesSTAT5A, MGF, STAT5, signal transducer and activator of transcription 5A1.00infobox
STAT5AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y1U1.00infobox
STAT5ABand17q21.21.00infobox
STAT5ABand11 D|11 63.77 cM1.00infobox
STAT5ABgeegranulocyte1.00infobox
STAT5ABgeemonocyte1.00infobox
STAT5ABgeeleft adrenal cortex1.00infobox
STAT5ABgeeright adrenal cortex1.00infobox
STAT5ABgeesubcutaneous adipose tissue1.00infobox
STAT5ABgeetendon of biceps brachii1.00infobox
STAT5ABgeeblood1.00infobox
STAT5ABgeegastric mucosa1.00infobox
STAT5ABgeeappendix1.00infobox
STAT5ABgeelymph node1.00infobox
STAT5ABgeelactiferous gland1.00infobox
STAT5ABgeeseminal vesicula1.00infobox
STAT5ABgeeIleal epithelium1.00infobox
STAT5ABgeethymus1.00infobox
STAT5ABgeebrown adipose tissue1.00infobox
STAT5ABgeecumulus cell1.00infobox
STAT5ABgeeperirhinal cortex1.00infobox
STAT5ABgeeparotid gland1.00infobox
STAT5ABgeechoroid plexus of fourth ventricle1.00infobox
STAT5ABioGPSMore reference expression data1.00infobox
STAT5AChr.Chromosome 17 (human)1.00infobox
STAT5AChr.Chromosome 11 (mouse)1.00infobox
STAT5ADatabasesNCBI: entry; OMA: entry1.00infobox
STAT5AEnd42,311,943 bp1.00infobox
STAT5AEnd100,775,995 bp1.00infobox
STAT5AEnsemblENSG000001265611.00infobox

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