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Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. STAT5A orthologs have been identified in several placentals for which complete genome data are available.
The analysis highlights Interactions, Clinical signficance and Structure as prominent areas in the source structure around STAT5A.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around STAT5A shows recurring relationship patterns in the source. For example, STAT5A → 2-oxoglutarate metabolic process, allantoin metabolic process, citrate metabolic process, creatine metabolic process, creatinine metabolic process, cytokine-mediated signaling pathway, cytoplasm, cytosol, defense response, DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, fatty acid metabolic process, growth hormone receptor signaling pathway via JAK-STAT, interleukin-15-mediated signaling pathway, interleukin-2-mediated signaling pathway, interleukin-7-mediated signaling pathway, interleukin-9-mediated signaling pathway, isoleucine metabolic process Another extracted example is STAT5A → appendix, blood, brown adipose tissue, choroid plexus of fourth ventricle, cumulus cell, gastric mucosa, granulocyte, Ileal epithelium, lactiferous gland, left adrenal cortex, lymph node, monocyte, parotid gland, perirhinal cortex, right adrenal cortex, seminal vesicula, subcutaneous adipose tissue, tendon of biceps brachii, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
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TTTA extracted 146 structured relationships around STAT5A. Examples in this analysis include STAT5A → Aliases → STAT5A, MGF, STAT5, signal transducer and activator of transcription 5A and STAT5A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y1U. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| STAT5A | Aliases | STAT5A, MGF, STAT5, signal transducer and activator of transcription 5A | 1.00 | infobox |
| STAT5A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1Y1U | 1.00 | infobox |
| STAT5A | Band | 17q21.2 | 1.00 | infobox |
| STAT5A | Band | 11 D|11 63.77 cM | 1.00 | infobox |
| STAT5A | Bgee | granulocyte | 1.00 | infobox |
| STAT5A | Bgee | monocyte | 1.00 | infobox |
| STAT5A | Bgee | left adrenal cortex | 1.00 | infobox |
| STAT5A | Bgee | right adrenal cortex | 1.00 | infobox |
| STAT5A | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| STAT5A | Bgee | tendon of biceps brachii | 1.00 | infobox |
| STAT5A | Bgee | blood | 1.00 | infobox |
| STAT5A | Bgee | gastric mucosa | 1.00 | infobox |
| STAT5A | Bgee | appendix | 1.00 | infobox |
| STAT5A | Bgee | lymph node | 1.00 | infobox |
| STAT5A | Bgee | lactiferous gland | 1.00 | infobox |
| STAT5A | Bgee | seminal vesicula | 1.00 | infobox |
| STAT5A | Bgee | Ileal epithelium | 1.00 | infobox |
| STAT5A | Bgee | thymus | 1.00 | infobox |
| STAT5A | Bgee | brown adipose tissue | 1.00 | infobox |
| STAT5A | Bgee | cumulus cell | 1.00 | infobox |
| STAT5A | Bgee | perirhinal cortex | 1.00 | infobox |
| STAT5A | Bgee | parotid gland | 1.00 | infobox |
| STAT5A | Bgee | choroid plexus of fourth ventricle | 1.00 | infobox |
| STAT5A | BioGPS | More reference expression data | 1.00 | infobox |
| STAT5A | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| STAT5A | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| STAT5A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| STAT5A | End | 42,311,943 bp | 1.00 | infobox |
| STAT5A | End | 100,775,995 bp | 1.00 | infobox |
| STAT5A | Ensembl | ENSG00000126561 | 1.00 | infobox |
The concept neighborhoods around STAT5A bring nearby vocabulary together. In this analysis, examples include Cancer, Prostate and Shown. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For STAT5A, one of the stronger structural bridges in this analysis connects STAT5A with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around STAT5A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Clinical signficance & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — STAT5A · EN edition · Analysis: TopicsToTalkAbout