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Cell-mediated immunity

Cellular immunity, also known as cell-mediated immunity, is an immune response that does not rely on the production of antibodies. Rather, cell-mediated immunity is the activation of phagocytes, antigen-specific cytotoxic T cells (a.k.a. cytotoxic T lymphocytes), and the release of various cytokines in response to an antigen.

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Overview

History

Role of dendritic cells in cell-mediated immunity

Synopsis

Development of cells

Type 1 immunity

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Cell-mediated immunity

Nodes100
Edges99
Triples46
Avg. degree1.98
Density0.02
Components1

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Cell-mediated immunity

Top relations

related to Role of dendritic cells in cell-mediated immunity · 16
Cell-mediated immunity → Acting, C-C, CCL19, CCL21, CCL5, CCR7, CD80, CD86, DCs, IL-12, IL-2, Myeloid, Once DCs, Said, T-cell, T-cells
related to Bibliography · 9
Cell-mediated immunity → Cell-mediated, Cell-Mediated Immunity Immunobiology, Chapter, Disease, Encyclopædia Britannica, Health, Innate, The, The Immune System
related to Synopsis · 6
Cell-mediated immunity → Cellular, Macrophage, NK, Stimulating, T-cell, T-cell-mediated
related to Further reading · 2
Cell-mediated immunity → Cell-mediated, How
see also · 2
Cell-mediated immunity → Immune, Immunity
is a · 1
Cell-mediated immunity → activation of phagocytes

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Important terminology

cells immunity cell-mediated also cytokines cytotoxic type th1 innate interferon gamma may immune cd4 activation response macrophages il-12 antigen dcs

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cell-mediated immunityis aactivation of phagocytes0.90text
CCL5instance ofthey release chemokines0.80text
CCR7 that help recruitinstance ofthey release chemokines0.80text
position naïve T-cellsinstance ofthey release chemokines0.80text
other leukocytes within the lymph node for antigen recognitioninstance ofthey release chemokines0.80text
CD80instance ofDCs then supply additional activation signals to T-cells by expressing co-stimulatory proteins0.80text
CD86instance ofDCs then supply additional activation signals to T-cells by expressing co-stimulatory proteins0.80text
by secreting cytokines like interleukin 12instance ofDCs then supply additional activation signals to T-cells by expressing co-stimulatory proteins0.80text
rheumatoid arthritisinstance ofIt is also responsible for inflammation and autoimmunity with diseases0.80text
multiple sclerosisinstance ofIt is also responsible for inflammation and autoimmunity with diseases0.80text
and inflammatory bowel disease all being implicated in type 1 immunityinstance ofIt is also responsible for inflammation and autoimmunity with diseases0.80text
Cell-mediated immunityrelated to BibliographyCell-mediated0.60section

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