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C-X-C motif chemokine ligand 10 (CXCL10), also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10, is an 8.7 kDa protein that in humans is encoded by the CXCL10 gene. C-X-C motif chemokine 10 is a small cytokine belonging to the CXC chemokine family.
The analysis highlights Function, Clinical significance and Biomarkers as prominent areas in the source structure around CXCL10.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around CXCL10 shows recurring relationship patterns in the source. For example, CXCL10 → adenylate cyclase-activating G protein-coupled receptor signaling pathway, antimicrobial humoral immune response mediated by antimicrobial peptide, blood circulation, cAMP-dependent protein kinase regulator activity, cell surface receptor signaling pathway, cell-cell signaling, cellular response to heat, cellular response to lipopolysaccharide, chemoattractant activity, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, CXCR3 chemokine receptor binding, cytokine activity, cytokine-mediated signaling pathway, defense response, defense response to virus, endothelial cell activation, external side of plasma membrane, extracellular region Another extracted example is CXCL10 → appendix, decidua, embryo, epithelium of nasopharynx, granulocyte, lymph node, mesenteric lymph nodes, monocyte, olfactory zone of nasal mucosa, optic nerve, rectum, right kidney, smooth muscle tissue, spermatocyte, spleen, subcutaneous adipose tissue, testicle, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
gene chemokine human bp chr band chromosome location c-x-c motif 10 cytokine cell protein external response ip-10 structure cxcr3 mouse
TTTA extracted 152 structured relationships around CXCL10. Examples in this analysis include CXCL10 → Aliases → CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10 and CXCL10 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1O80, 1LV9, 1O7Y, 1O7Z. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CXCL10 | Aliases | CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1, C-X-C motif chemokine ligand 10, C-X-C motif chemokine 10 | 1.00 | infobox |
| CXCL10 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1O80, 1LV9, 1O7Y, 1O7Z | 1.00 | infobox |
| CXCL10 | Band | 4q21.1 | 1.00 | infobox |
| CXCL10 | Band | 5 E2|5 46.57 cM | 1.00 | infobox |
| CXCL10 | Bgee | appendix | 1.00 | infobox |
| CXCL10 | Bgee | testicle | 1.00 | infobox |
| CXCL10 | Bgee | decidua | 1.00 | infobox |
| CXCL10 | Bgee | lymph node | 1.00 | infobox |
| CXCL10 | Bgee | rectum | 1.00 | infobox |
| CXCL10 | Bgee | monocyte | 1.00 | infobox |
| CXCL10 | Bgee | granulocyte | 1.00 | infobox |
| CXCL10 | Bgee | olfactory zone of nasal mucosa | 1.00 | infobox |
| CXCL10 | Bgee | smooth muscle tissue | 1.00 | infobox |
| CXCL10 | Bgee | epithelium of nasopharynx | 1.00 | infobox |
| CXCL10 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| CXCL10 | Bgee | thymus | 1.00 | infobox |
| CXCL10 | Bgee | spleen | 1.00 | infobox |
| CXCL10 | Bgee | spermatocyte | 1.00 | infobox |
| CXCL10 | Bgee | optic nerve | 1.00 | infobox |
| CXCL10 | Bgee | embryo | 1.00 | infobox |
| CXCL10 | Bgee | right kidney | 1.00 | infobox |
| CXCL10 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| CXCL10 | BioGPS | More reference expression data | 1.00 | infobox |
| CXCL10 | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| CXCL10 | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| CXCL10 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CXCL10 | End | 76,023,497 bp | 1.00 | infobox |
| CXCL10 | End | 92,496,748 bp | 1.00 | infobox |
| CXCL10 | Ensembl | ENSG00000169245 | 1.00 | infobox |
| CXCL10 | Entrez | 3627 | 1.00 | infobox |
The concept neighborhoods around CXCL10 bring nearby vocabulary together. In this analysis, examples include Gene, Development and Plasma. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For CXCL10, one of the stronger structural bridges in this analysis connects CXCL10 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around CXCL10 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Clinical significance & Biomarkers, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CXCL10 · EN edition · Analysis: TopicsToTalkAbout