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C-C chemokine receptor type 7 is a protein that in humans is encoded by the CCR7 gene. Two ligands have been identified for this receptor: the chemokine (C-C motif) ligand 19 (CCL19/ELC) and (C-C motif) ligand 21 (CCL21). The ligands have similar affinity for the receptor, though CCL19 has been shown to induce internalisation of CCR7 and desensitisation…
The analysis highlights Function and Overview as prominent areas in the source structure around C-C chemokine receptor type 7.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around C-C chemokine receptor type 7 shows recurring relationship patterns in the source. For example, C-C chemokine receptor type 7 → activation of GTPase activity, C-C chemokine binding, C-C chemokine receptor activity, C-C motif chemokine 19 receptor activity, C-C motif chemokine 21 receptor activity, calcium-mediated signaling, cell chemotaxis, cell surface, cellular response to cytokine stimulus, chemokine (C-C motif) ligand 19 binding, chemokine (C-C motif) ligand 19 signaling pathway, chemokine (C-C motif) ligand 21 binding, chemokine (C-C motif) ligand 21 signaling pathway, chemokine binding, chemokine receptor activity, chemokine-mediated signaling pathway, chemotaxis, dendritic cell chemotaxis, establishment of T cell polarity, external side of plasma membrane Another extracted example is C-C chemokine receptor type 7 → appendix, blood, bone marrow, embryo, granulocyte, lymph node, mesenteric lymph nodes, mucosa of ileum, right lung lobe, spleen, subcutaneous adipose tissue, superficial temporal artery, testicle, thymus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
ccr7 receptor cells cell human dendritic gene also thymus bp expression lymph nodes chr band ccl19 ccl21 protein c-c chemokine
TTTA extracted 122 structured relationships around C-C chemokine receptor type 7. Examples in this analysis include C-C chemokine receptor type 7 → Aliases → CCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 7 and C-C chemokine receptor type 7 → Band → 17q21.2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| C-C chemokine receptor type 7 | Aliases | CCR7, BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, C-C motif chemokine receptor 7 | 1.00 | infobox |
| C-C chemokine receptor type 7 | Band | 17q21.2 | 1.00 | infobox |
| C-C chemokine receptor type 7 | Band | 11|11 D | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | appendix | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | lymph node | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | blood | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | granulocyte | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | thymus | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | spleen | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | superficial temporal artery | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | mucosa of ileum | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | testicle | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | bone marrow | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | embryo | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | subcutaneous adipose tissue | 1.00 | infobox |
| C-C chemokine receptor type 7 | Bgee | right lung lobe | 1.00 | infobox |
| C-C chemokine receptor type 7 | BioGPS | More reference expression data | 1.00 | infobox |
| C-C chemokine receptor type 7 | Chr. | Chromosome 17 (human) | 1.00 | infobox |
| C-C chemokine receptor type 7 | Chr. | Chromosome 11 (mouse) | 1.00 | infobox |
| C-C chemokine receptor type 7 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| C-C chemokine receptor type 7 | End | 40,565,472 bp | 1.00 | infobox |
| C-C chemokine receptor type 7 | End | 99,045,903 bp | 1.00 | infobox |
| C-C chemokine receptor type 7 | Ensembl | ENSG00000126353 | 1.00 | infobox |
| C-C chemokine receptor type 7 | Entrez | 1236 | 1.00 | infobox |
| C-C chemokine receptor type 7 | External IDs | OMIM: 600242; MGI: 103011; GeneCards: CCR7 | 1.00 | infobox |
| C-C chemokine receptor type 7 | Gene location (Human) | Gene location (Human)Chr.Chromosome 17 (human)Band17q21.2Start40,553,769 bpEnd40,565,472 bp | 1.00 | infobox |
| C-C chemokine receptor type 7 | Gene location (Mouse) | Gene location (Mouse)Chr.Chromosome 11 (mouse)Band11|11 DStart99,035,022 bpEnd99,045,903 bp | 1.00 | infobox |
| C-C chemokine receptor type 7 | Gene ontology | C-C motif chemokine 19 receptor activity | 1.00 | infobox |
| C-C chemokine receptor type 7 | Gene ontology | C-C motif chemokine 21 receptor activity | 1.00 | infobox |
The concept neighborhoods around C-C chemokine receptor type 7 bring nearby vocabulary together. In this analysis, examples include Chemokine, Motif and External. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For C-C chemokine receptor type 7, one of the stronger structural bridges in this analysis connects C-C chemokine receptor type 7 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around C-C chemokine receptor type 7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — C-C chemokine receptor type 7 · EN edition · Analysis: TopicsToTalkAbout