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Asenapine: Applications & Standards

Asenapine, sold under the brand name Saphris among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder as well as the medium to long-term management of bipolar disorder.

Language: English [EN]
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Asenapine topic overview

The analysis highlights Applications and Standards as prominent areas in the source structure around Asenapine.

Related topics
96
Source areas
4
Connected nodes
100
Extracted relationships
81
Concept neighborhoods
18
Bridge connections
100

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 52 topics
Pharmacology · 29 topics
Medical uses · 9 topics
Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AH05 (WHO)
Bioavailability
35% (sublingual), <2% (oral), transdermal bioavailability is significantly higher than sublingual
CAS Number
65576-45-6 N · as salt: 85650-56-2
ChEBI
CHEBI:71253 N · as salt: CHEBI:71245

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Pharmacology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Asenapine connects Entity context

The extracted context around Asenapine shows recurring relationship patterns in the source. For example, Asenapine → At, D1, D2, D3, D4, Even, H1, H2, HT1A, HT1B, HT2A, HT2B, HT2C, HT5A, HT6, HT7, It Another extracted example is Asenapine → Archived, Drug Information Portal, January, Medicine, National Library, October. Use these groups to spot repeated connection types before inspecting the individual relationships.

Asenapine

Top relations

related to Pharmacodynamics · 17
Asenapine → At, D1, D2, D3, D4, Even, H1, H2, HT1A, HT1B, HT2A, HT2B, HT2C, HT5A, HT6, HT7, It
related to External links · 6
Asenapine → Archived, Drug Information Portal, January, Medicine, National Library, October
Legal status · 5
Asenapine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Bipolar disorder · 5
Asenapine → According, As, Drop-out, For, In
related to Medical uses · 4
Asenapine → FDA, In Australia, PBS, SchizophreniaTreatment
License data · 3
Asenapine → EU EMA: by INN, US DailyMed: Asenapine, US FDA: Asenapine
CAS Number · 2
Asenapine → 65576-45-6 N, as salt: 85650-56-2
ChEBI · 2
Asenapine → as salt: CHEBI:71245, CHEBI:71253 N
ChEMBL · 2
Asenapine → as salt: ChEMBL2040684, ChEMBL1201756 N
ChemSpider · 2
Asenapine → 2300725 Y, as salt: 5293095

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

atypical acute schizophrenia disorder bipolar antipsychotic mania symptoms name significantly olanzapine receptors include found meta-analysis approved medication effects drug transdermal

Asenapine relationships Subject–Predicate–Object triples

TTTA extracted 81 structured relationships around Asenapine. Examples in this analysis include Asenapine → 3D model (JSmol) → Interactive image and Asenapine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Asenapine3D model (JSmol)Interactive image1.00infobox
AsenapineAHFS/Drugs.comMonograph1.00infobox
AsenapineATC codeN05AH05 (WHO)1.00infobox
AsenapineBioavailability35% (sublingual), <2% (oral), transdermal bioavailability is significantly higher than sublingual1.00infobox
AsenapineCAS Number65576-45-6 N1.00infobox
AsenapineCAS Numberas salt: 85650-56-21.00infobox
AsenapineChEBICHEBI:71253 N1.00infobox
AsenapineChEBIas salt: CHEBI:712451.00infobox
AsenapineChEMBLChEMBL1201756 N1.00infobox
AsenapineChEMBLas salt: ChEMBL20406841.00infobox
AsenapineChemSpider2300725 Y1.00infobox
AsenapineChemSpideras salt: 52930951.00infobox
AsenapineDrug classAtypical antipsychotic1.00infobox
AsenapineDrugBankDB062161.00infobox
AsenapineDrugBankas salt: DBSALT0000101.00infobox
AsenapineECHA InfoCard100.059.8281.00infobox
AsenapineElimination half-life24 hours (sublingual), 30 hours (transdermal), 33.9 hours (transdermal)1.00infobox
AsenapineExcretionKidney (50%), Fecal (40%; ~5–16% as unchanged drug in feces)1.00infobox
AsenapineFormulaC17H16ClNO1.00infobox
AsenapineIUPHAR/BPS221.00infobox
AsenapineKEGGD117691.00infobox
AsenapineKEGGas salt: D029951.00infobox
AsenapineLegal statusAU: S4 (Prescription only)1.00infobox
AsenapineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
AsenapineLegal statusUK: POM (Prescription only)1.00infobox
AsenapineLegal statusUS: ℞-only1.00infobox
AsenapineLegal statusEU: Rx-only1.00infobox
AsenapineLicense dataEU EMA: by INN1.00infobox
AsenapineLicense dataUS DailyMed: Asenapine1.00infobox
AsenapineLicense dataUS FDA: Asenapine1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Asenapine bring nearby vocabulary together. In this analysis, examples include Disorder, Found and Atypical. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Asenapine
    • Disorder
    • Found
    • Atypical
    • Bipolar
    • High
    • Name
    • Schizophrenia
    • Significantly
    • Antipsychotic
    • Acute
    • Associated
    • Transdermal
  • asenapine
    • Disorder
    • Found
    • Atypical
    • Bipolar
    • High
    • Name
    • Schizophrenia
    • Significantly
    • Antipsychotic
    • Acute
    • Associated
    • Transdermal
  • atypical antipsychotic
    • Name
    • Olanzapine
    • Significantly
    • Disorder
    • Meta-analysis
    • Saphris
    • Atypical
    • Acute
    • Adverse
    • Associated
    • Manic
    • Oral
  • bipolar disorder
    • Disorder
    • Schizophrenia
    • Saphris
    • Manic
    • Adverse
    • Approved
    • Episodes
    • Mixed
    • Name
    • Oral
    • Treatment
    • Drug
  • adverse effects
    • Oral
    • Effects
    • Dyskinesia
    • Drug
    • Side
    • Significantly
    • Antipsychotic
    • Disorder
    • Episodes
    • Include
    • Mixed
    • Atypical
  • mania
    • Episodes
    • Mixed
    • Associated
    • Bipolar
    • Schizophrenia
    • Treatment
    • Disorder
    • Saphris
    • Manic
    • Medication
    • United
    • Also
  • extrapyramidal side effects
    • Oral
    • Dyskinesia
    • Drug
    • Episodes
    • Mixed
    • Side
    • Significantly
    • Include
    • Saphris
    • Manic
    • Transdermal
    • May
  • schizophrenia
    • Treatment
    • Episodes
    • Mixed
    • Manic
    • Oral
    • Transdermal
    • United
    • Also
    • Drug
    • Significantly
    • Found
    • Include

Connections between topic areas Semantic bridges

For Asenapine, one of the stronger structural bridges in this analysis connects Asenapine with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
AsenapineAdverse effects · splits 48 ⟂ 53
AsenapinePharmacology · splits 71 ⟂ 30
AsenapineMedical uses · splits 91 ⟂ 10
AsenapineOverview · splits 94 ⟂ 7

Map overview Semantic statistics

Asenapine

Nodes101
Edges100
Triples81
Avg. degree1.98
Density0.019802
Components1

Source & methodology

TTTA analyzes the structure around Asenapine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Asenapine · EN edition · Analysis: TopicsToTalkAbout

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