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Asenapine

Asenapine, sold under the brand name Saphris among others, is an atypical antipsychotic medication used to treat schizophrenia and acute mania associated with bipolar disorder as well as the medium to long-term management of bipolar disorder.

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Explore the main themes, entities and connections around Asenapine. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AH05 (WHO)
Bioavailability
35% (sublingual), <2% (oral), transdermal bioavailability is significantly higher than sublingual
CAS Number
65576-45-6 N · as salt: 85650-56-2
ChEBI
CHEBI:71253 N · as salt: CHEBI:71245

Topics to explore

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Overview

Medical uses

Adverse effects

Pharmacology

Advanced semantic analysis

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Map overview Semantic statistics

Asenapine

Nodes101
Edges100
Triples81
Avg. degree1.98
Density0.019802
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Asenapine

Top relations

related to Pharmacodynamics · 17
Asenapine → At, D1, D2, D3, D4, Even, H1, H2, HT1A, HT1B, HT2A, HT2B, HT2C, HT5A, HT6, HT7, It
related to External links · 6
Asenapine → Archived, Drug Information Portal, January, Medicine, National Library, October
Legal status · 5
Asenapine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), EU: Rx-only, UK: POM (Prescription only), US: ℞-only
related to Bipolar disorder · 5
Asenapine → According, As, Drop-out, For, In
related to Medical uses · 4
Asenapine → FDA, In Australia, PBS, SchizophreniaTreatment
License data · 3
Asenapine → EU EMA: by INN, US DailyMed: Asenapine, US FDA: Asenapine
CAS Number · 2
Asenapine → 65576-45-6 N, as salt: 85650-56-2
ChEBI · 2
Asenapine → as salt: CHEBI:71245, CHEBI:71253 N
ChEMBL · 2
Asenapine → as salt: ChEMBL2040684, ChEMBL1201756 N
ChemSpider · 2
Asenapine → 2300725 Y, as salt: 5293095

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

atypical acute schizophrenia disorder bipolar antipsychotic mania symptoms name significantly olanzapine receptors include found meta-analysis approved medication effects drug transdermal

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Asenapine3D model (JSmol)Interactive image1.00infobox
AsenapineAHFS/Drugs.comMonograph1.00infobox
AsenapineATC codeN05AH05 (WHO)1.00infobox
AsenapineBioavailability35% (sublingual), <2% (oral), transdermal bioavailability is significantly higher than sublingual1.00infobox
AsenapineCAS Number65576-45-6 N1.00infobox
AsenapineCAS Numberas salt: 85650-56-21.00infobox
AsenapineChEBICHEBI:71253 N1.00infobox
AsenapineChEBIas salt: CHEBI:712451.00infobox
AsenapineChEMBLChEMBL1201756 N1.00infobox
AsenapineChEMBLas salt: ChEMBL20406841.00infobox
AsenapineChemSpider2300725 Y1.00infobox
AsenapineChemSpideras salt: 52930951.00infobox
AsenapineDrug classAtypical antipsychotic1.00infobox
AsenapineDrugBankDB062161.00infobox
AsenapineDrugBankas salt: DBSALT0000101.00infobox
AsenapineECHA InfoCard100.059.8281.00infobox
AsenapineElimination half-life24 hours (sublingual), 30 hours (transdermal), 33.9 hours (transdermal)1.00infobox
AsenapineExcretionKidney (50%), Fecal (40%; ~5–16% as unchanged drug in feces)1.00infobox
AsenapineFormulaC17H16ClNO1.00infobox
AsenapineIUPHAR/BPS221.00infobox
AsenapineKEGGD117691.00infobox
AsenapineKEGGas salt: D029951.00infobox
AsenapineLegal statusAU: S4 (Prescription only)1.00infobox
AsenapineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
AsenapineLegal statusUK: POM (Prescription only)1.00infobox
AsenapineLegal statusUS: ℞-only1.00infobox
AsenapineLegal statusEU: Rx-only1.00infobox
AsenapineLicense dataEU EMA: by INN1.00infobox
AsenapineLicense dataUS DailyMed: Asenapine1.00infobox
AsenapineLicense dataUS FDA: Asenapine1.00infobox

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