Alpha-2B adrenergic receptor

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Alpha-2B adrenergic receptor topic overview

The analysis highlights Clinical significance, Evolution and Ligands as prominent areas in the source structure around Alpha-2B adrenergic receptor.

Related topics: 31
Source areas: 5
Connected nodes: 36
Extracted relationships: 92
Concept neighborhoods: 10
Bridge connections: 36

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical significance · 13 topics

Evolution · 6 topics

Overview · 5 topics

Ligands · 4 topics

Receptor · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR, FAME2, adrenoceptor alpha 2B
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CVA
Band: 2q11.2 · 2 F1|2 61.95 cM
Bgee: apex of heart · gastrocnemius muscle · left ventricle · right lobe of liver · spleen
BioGPS: n/a
Chr.: Chromosome 2 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Receptor

Clinical significance

EIF-2B
Guanine nucleotide exchange protein
Translation MRNA translation
Glutamic acids Glutamic acid
Repeat element
Kinase
Desensitization Desensitization (medicine)
Basal metabolic rate
Obese
Introns
Coding Coding region
Untranslated sequences Untranslated sequence
Reboxetine

Evolution

Ligands

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Alpha-2B adrenergic receptor connects Entity context

The extracted context around Alpha-2B adrenergic receptor shows recurring relationship patterns in the source. For example, Alpha-2B adrenergic receptor → activation of protein kinase B activity, adenylate cyclase-activating adrenergic receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, adrenergic receptor activity, adrenergic receptor signaling pathway, alpha2-adrenergic receptor activity, cell surface, cell-cell signaling, epinephrine binding, female pregnancy, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, membrane, negative regulation of epinephrine secretion, negative regulation of norepinephrine secretion, plasma membrane, platelet activation Another extracted example is Alpha-2B adrenergic receptor → apex of heart, ascending aorta, decidua, embryo, gastric mucosa, gastrocnemius muscle, hepatobiliary system, human kidney, left ventricle, liver, muscle of thigh, proximal tubule, right kidney, right lobe of liver, secondary oocyte, spleen, subcutaneous adipose tissue, tibial nerve, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 31

Alpha-2B adrenergic receptor → activation of protein kinase B activity, adenylate cyclase-activating adrenergic receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, adrenergic receptor activity, adrenergic receptor signaling pathway, alpha2-adrenergic receptor activity, cell surface, cell-cell signaling, epinephrine binding, female pregnancy, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, integral component of membrane, integral component of plasma membrane, intracellular anatomical structure, membrane, negative regulation of epinephrine secretion, negative regulation of norepinephrine secretion, plasma membrane, platelet activation

Bgee · 19

Alpha-2B adrenergic receptor → apex of heart, ascending aorta, decidua, embryo, gastric mucosa, gastrocnemius muscle, hepatobiliary system, human kidney, left ventricle, liver, muscle of thigh, proximal tubule, right kidney, right lobe of liver, secondary oocyte, spleen, subcutaneous adipose tissue, tibial nerve, yolk sac

RNA expression pattern · 19

Band · 2

Alpha-2B adrenergic receptor → 2 F1|2 61.95 cM, 2q11.2

Chr. · 2

Alpha-2B adrenergic receptor → Chromosome 2 (human), Chromosome 2 (mouse)

End · 2

Alpha-2B adrenergic receptor → 127,209,141 bp, 96,116,571 bp

Aliases · 1

Alpha-2B adrenergic receptor → ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR, FAME2, adrenoceptor alpha 2B

Available structures · 1

Alpha-2B adrenergic receptor → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CVA

BioGPS · 1

Alpha-2B adrenergic receptor → n/a

Databases · 1

Alpha-2B adrenergic receptor → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene receptor adra2b human bp adrenergic chr band α2b chromosome location also orthologs variant subtype mouse mammals protein adrenoceptor external

Alpha-2B adrenergic receptor relationships Subject–Predicate–Object triples

TTTA extracted 92 structured relationships around Alpha-2B adrenergic receptor. Examples in this analysis include Alpha-2B adrenergic receptor → Aliases → ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR, FAME2, adrenoceptor alpha 2B and Alpha-2B adrenergic receptor → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CVA. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Alpha-2B adrenergic receptor	Aliases	ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR, FAME2, adrenoceptor alpha 2B	1.00	infobox
Alpha-2B adrenergic receptor	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CVA	1.00	infobox
Alpha-2B adrenergic receptor	Band	2q11.2	1.00	infobox
Alpha-2B adrenergic receptor	Band	2 F1\|2 61.95 cM	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	apex of heart	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	gastrocnemius muscle	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	left ventricle	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	right lobe of liver	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	spleen	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	subcutaneous adipose tissue	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	muscle of thigh	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	tibial nerve	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	ascending aorta	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	gastric mucosa	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	right kidney	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	proximal tubule	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	human kidney	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	yolk sac	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	decidua	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	embryo	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	hepatobiliary system	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	liver	1.00	infobox
Alpha-2B adrenergic receptor	Bgee	secondary oocyte	1.00	infobox
Alpha-2B adrenergic receptor	BioGPS	n/a	1.00	infobox
Alpha-2B adrenergic receptor	Chr.	Chromosome 2 (human)	1.00	infobox
Alpha-2B adrenergic receptor	Chr.	Chromosome 2 (mouse)	1.00	infobox
Alpha-2B adrenergic receptor	Databases	NCBI: entry; OMA: entry	1.00	infobox
Alpha-2B adrenergic receptor	End	96,116,571 bp	1.00	infobox
Alpha-2B adrenergic receptor	End	127,209,141 bp	1.00	infobox
Alpha-2B adrenergic receptor	Ensembl	ENSG00000274286	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Alpha-2B adrenergic receptor bring nearby vocabulary together. In this analysis, examples include Receptor, Α2b and Intracellular. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Alpha-2B adrenergic receptor
- Receptor
- Α2b
- Intracellular
- Receptors
- System
- Ucsc
- Location
- Also
- Human
- Variant
- Adra2b
- Bp
alpha-2b adrenergic receptor
- Receptor
- Α2b
- Human
- Adra2b
- Intracellular
- Location
- Receptors
- System
- Ucsc
- Gene
- Adrenoceptor
- Associated
g-protein coupled receptor
- Α2b
- Human
- Adra2b
- Location
- Gene
- Adrenoceptor
- Associated
- Intracellular
- Protein-coupled
- Search
- Ucsc
- Subtype
adrenergic receptor
- Receptor
- Α2b
- Human
- Adra2b
- Intracellular
- Location
- Receptors
- System
- Ucsc
- Gene
- Adrenoceptor
- Associated
gene
- Human
- Adra2b
- Location
- Receptor
- Chromosome
- Bp
- Chr
- End
- F1
- Intracellular
- Mouse
- Regulation
receptor
- Α2b
- Human
- Adra2b
- Location
- Gene
- Adrenoceptor
- Associated
- Intracellular
- Protein-coupled
- Search
- Ucsc
- Subtype
guanine nucleotide exchange protein
- Regulation
- Α2b
- Negative
- Orthologs
- Protein-coupled
- Receptors
- Search
- System
- Ucsc
- Subtype
- Receptor
orthologs
- Protein-coupled
- Receptors
- Regulation
- Search
- System
- Ucsc
- Protein
- Α2b
- Receptor

Connections between topic areas Semantic bridges

For Alpha-2B adrenergic receptor, one of the stronger structural bridges in this analysis connects Alpha-2B adrenergic receptor with Clinical significance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Alpha-2B adrenergic receptor — Clinical significance · splits 23 ⟂ 14

Alpha-2B adrenergic receptor — Evolution · splits 30 ⟂ 7

Alpha-2B adrenergic receptor — Overview · splits 31 ⟂ 6

Alpha-2B adrenergic receptor — Ligands · splits 32 ⟂ 5

Alpha-2B adrenergic receptor — Receptor · splits 33 ⟂ 4

Map overview Semantic statistics

Alpha-2B adrenergic receptor

Nodes37

Edges36

Triples92

Avg. degree1.95

Density0.054054

Components1

Source & methodology

TTTA analyzes the structure around Alpha-2B adrenergic receptor to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Clinical significance, Evolution & Ligands, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Alpha-2B adrenergic receptor · EN edition · Analysis: TopicsToTalkAbout