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Iloperidone

Iloperidone, sold under the brand name Fanapt among others, is an atypical antipsychotic for the treatment of schizophrenia and bipolar I disorder.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AX14 (WHO)
Bioavailability
96% (oral; Tmax = 2–4 hours)
CAS Number
133454-47-4 Y
ChEBI
CHEBI:65173 N

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Overview

Medical uses

Side effects

Pharmacology

History

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Map overview Semantic statistics

Iloperidone

Nodes33
Edges32
Triples66
Avg. degree1.94
Density0.060606
Components1

How this topic connects Entity context

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Iloperidone

Top relations

related to history · 19
Iloperidone → April, August, Drug Administration, FDA, Food, Hoechst Marion Roussel Inc, June, May, New Drug Application, Novartis, On July, On June, On November, Phase III, The, Titan, Titan Pharmaceuticals, United States, Vanda Pharmaceuticals
related to Pharmacology · 14
Iloperidone → Antagonism, D1, D2, D3, D4, H1, HT1A, HT2A, HT6, HT7, In, It, Ki, The
has effect · 4
Iloperidone → Examination, However, The, This
License data · 2
Iloperidone → US DailyMed: Iloperidone, US FDA: Iloperidone
related to Medical uses · 2
Iloperidone → In, It
3D model (JSmol) · 1
Iloperidone → Interactive image
AHFS/Drugs.com · 1
Iloperidone → Monograph
ATC code · 1
Iloperidone → N05AX14 (WHO)
Bioavailability · 1
Iloperidone → 96% (oral; Tmax = 2–4 hours)
CAS Number · 1
Iloperidone → 133454-47-4 Y

Important terminology Word statistics

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Important terminology

antipsychotic schizophrenia effects drug serotonin symptoms may treatment fda administration fanapt atypical withdrawal antipsychotics pharmaceuticals bipolar disorder dopamine also name

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Iloperidone3D model (JSmol)Interactive image1.00infobox
IloperidoneAHFS/Drugs.comMonograph1.00infobox
IloperidoneATC codeN05AX14 (WHO)1.00infobox
IloperidoneBioavailability96% (oral; Tmax = 2–4 hours)1.00infobox
IloperidoneCAS Number133454-47-4 Y1.00infobox
IloperidoneChEBICHEBI:65173 N1.00infobox
IloperidoneChEMBLChEMBL14376 Y1.00infobox
IloperidoneChemSpider64459 Y1.00infobox
IloperidoneCompTox Dashboard (EPA)DTXSID60490601.00infobox
IloperidoneDrug classAtypical antipsychotic1.00infobox
IloperidoneECHA InfoCard100.106.4411.00infobox
IloperidoneElimination half-life18–33 hours1.00infobox
IloperidoneExcretionurine (45.1–58.2%) and feces (19.9–22.1%)1.00infobox
IloperidoneFormulaC24H27FN2O41.00infobox
IloperidoneIUPHAR/BPS871.00infobox
IloperidoneKEGGD02666 Y1.00infobox
IloperidoneLegal statusUS: ℞-only1.00infobox
IloperidoneLicense dataUS DailyMed: Iloperidone1.00infobox
IloperidoneLicense dataUS FDA: Iloperidone1.00infobox
IloperidoneMedlinePlusa6090261.00infobox
IloperidoneMetabolismHepatic (CYP2D6-mediated hydroxylation and CYP3A4-mediated O-demethylation)1.00infobox
IloperidoneMolar mass426.488 g·mol−11.00infobox
IloperidoneProtein binding~97%1.00infobox
IloperidonePubChem CID713601.00infobox
IloperidoneRoutes of administrationBy mouth, injection1.00infobox
IloperidoneTrade namesFanapt, Zomaril1.00infobox
IloperidoneUNIIVPO7KJ050N1.00infobox

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