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Amisulpride

Amisulpride, sold under the brand names Socian and Barhemsys, is a medication used in the treatment of schizophrenia, acute psychotic episodes, depression, and nausea and vomiting. It is specifically used at lower doses intravenously to prevent and treat postoperative nausea and vomiting, at low doses by mouth to treat depression, and at higher doses by…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AL05 (WHO)
Bioavailability
48%
CAS Number
71675-85-9 Y
ChEBI
CHEBI:64045 Y

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Overview

Medical uses

Contraindications

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

  • AU Australia
  • IE Ireland
  • RU Russian Federation
  • UK United Kingdom
  • ZA South Africa
  • IN India
  • BR Brazil
  • PT Portugal

Research

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Map overview Semantic statistics

Amisulpride

Nodes163
Edges162
Triples121
Avg. degree1.99
Density0.01227
Components1

How this topic connects Entity context

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Amisulpride

Top relations

related to United States clinical development · 14
Amisulpride → Canada, Drug Administration, Europe, FDA, Food, In Trial, IV, Neither, Subjects, The, Trial, Trials, Two, United States
related to Availability · 11
Amisulpride → An IV, Asia, Australia, Drug Administration, Europe, February, Food, Mexico, New Zealand, PONV, United States
related to Depression · 10
Amisulpride → Cochrane, D2, D2-like, D3, European, Greece, Italy, Likewise, The, Whereas
related to Pharmacodynamics · 7
Amisulpride → Although, D2, D3, GHB, IC50Tooltip Half-maximal, It, This
related to Bipolar depression · 6
Amisulpride → D2, However, HT7, SEP-4199, Sunovion Pharmaceuticals, United States
related to Contraindications · 5
Amisulpride → Amisulpride's, LactationChildren, Lewy, Parkinson's, PheochromocytomaConcomitant
related to External links · 5
Amisulpride → Archived, Drug Information Portal, February, Medicine, National Library
Legal status · 4
Amisulpride → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), UK: POM (Prescription only), US: ℞-only
related to Chemical derivatives · 4
Amisulpride → LB Pharmaceuticals, LB-102, N-methylamisulpride, United States
related to Interactions · 3
Amisulpride → QT, Torsades, Ventricular

Important terminology Word statistics

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Important terminology

nausea vomiting dopamine d2 treatment receptor schizophrenia use states depression subjects used united treat antipsychotics dysthymia 5-ht7 postoperative drug antidepressant

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Amisulpride3D model (JSmol)Interactive image1.00infobox
AmisulprideAHFS/Drugs.comMonograph1.00infobox
AmisulprideATC codeN05AL05 (WHO)1.00infobox
AmisulprideBioavailability48%1.00infobox
AmisulprideCAS Number71675-85-9 Y1.00infobox
AmisulprideChEBICHEBI:64045 Y1.00infobox
AmisulprideChEMBLChEMBL243712 Y1.00infobox
AmisulprideChemSpider2074 Y1.00infobox
AmisulprideCompTox Dashboard (EPA)DTXSID50426131.00infobox
AmisulprideDrug classDopamine D2 and D3 receptor antagonist; Serotonin 5-HT2B and 5-HT7 receptor antagonist; Antipsychotic; Antidepressant; Antiemetic1.00infobox
AmisulprideDrugBankDB06288 Y1.00infobox
AmisulprideECHA InfoCard100.068.9161.00infobox
AmisulprideElimination half-life12 hours1.00infobox
AmisulprideExcretionKidney (23–46%), Faecal1.00infobox
AmisulprideFormulaC17H27N3O4S1.00infobox
AmisulprideIUPHAR/BPS9631.00infobox
AmisulprideKEGGD07310 Y1.00infobox
AmisulprideLegal statusAU: S4 (Prescription only)1.00infobox
AmisulprideLegal statusBR: Class C1 (Other controlled substances)1.00infobox
AmisulprideLegal statusUK: POM (Prescription only)1.00infobox
AmisulprideLegal statusUS: ℞-only1.00infobox
AmisulprideLicense dataUS DailyMed: Amisulpride1.00infobox
AmisulprideLicense dataUS FDA: Barhemsys1.00infobox
AmisulprideMetabolismLiver (minimal; most excreted unchanged)1.00infobox
AmisulprideMolar mass369.48 g·mol−11.00infobox
AmisulprideOther namesAminosultopride; AST; APD-421; APD421; APD-403; APD403; DAN-2163; DAN21631.00infobox
AmisulpridePregnancy categoryAU: C1.00infobox
AmisulprideProtein binding16%1.00infobox
AmisulpridePubChem CID21591.00infobox
AmisulprideRoutes of administrationBy mouth, intravenous1.00infobox

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