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Amisulpride: History, Community, Culture & Applications

Amisulpride, sold under the brand names Socian and Barhemsys, is a medication used in the treatment of schizophrenia, acute psychotic episodes, depression, and nausea and vomiting. It is specifically used at lower doses intravenously to prevent and treat postoperative nausea and vomiting, at low doses by mouth to treat depression, and at higher doses by…

Language: English [EN]
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Amisulpride topic overview

The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Amisulpride.

Related topics
151
Source areas
11
Connected nodes
162
Extracted relationships
121
Concept neighborhoods
31
Bridge connections
162

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 39 topics
Adverse effects · 27 topics
Pharmacology · 25 topics
Medical uses · 15 topics
Chemistry · 12 topics
Research · 10 topics
Society and culture · 8 topics
Interactions · 6 topics
Contraindications · 5 topics
Overdose · 3 topics
History · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AL05 (WHO)
Bioavailability
48%
CAS Number
71675-85-9 Y
ChEBI
CHEBI:64045 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects

Overdose

Interactions

Pharmacology

Chemistry

History

Society and culture

  • AU Australia
  • IE Ireland
  • RU Russian Federation
  • UK United Kingdom
  • ZA South Africa
  • IN India
  • BR Brazil
  • PT Portugal

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Amisulpride connects Entity context

The extracted context around Amisulpride shows recurring relationship patterns in the source. For example, Amisulpride → Canada, Drug Administration, Europe, FDA, Food, In Trial, IV, Neither, Subjects, The, Trial, Trials, Two, United States Another extracted example is Amisulpride → An IV, Asia, Australia, Drug Administration, Europe, February, Food, Mexico, New Zealand, PONV, United States. Use these groups to spot repeated connection types before inspecting the individual relationships.

Amisulpride

Top relations

related to United States clinical development · 14
Amisulpride → Canada, Drug Administration, Europe, FDA, Food, In Trial, IV, Neither, Subjects, The, Trial, Trials, Two, United States
related to Availability · 11
Amisulpride → An IV, Asia, Australia, Drug Administration, Europe, February, Food, Mexico, New Zealand, PONV, United States
related to Depression · 10
Amisulpride → Cochrane, D2, D2-like, D3, European, Greece, Italy, Likewise, The, Whereas
related to Pharmacodynamics · 7
Amisulpride → Although, D2, D3, GHB, IC50Tooltip Half-maximal, It, This
related to Bipolar depression · 6
Amisulpride → D2, However, HT7, SEP-4199, Sunovion Pharmaceuticals, United States
related to Contraindications · 5
Amisulpride → Amisulpride's, LactationChildren, Lewy, Parkinson's, PheochromocytomaConcomitant
related to External links · 5
Amisulpride → Archived, Drug Information Portal, February, Medicine, National Library
Legal status · 4
Amisulpride → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), UK: POM (Prescription only), US: ℞-only
related to Chemical derivatives · 4
Amisulpride → LB Pharmaceuticals, LB-102, N-methylamisulpride, United States
related to Interactions · 3
Amisulpride → QT, Torsades, Ventricular

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

nausea vomiting dopamine d2 treatment receptor schizophrenia use states depression subjects used united treat antipsychotics dysthymia 5-ht7 postoperative drug antidepressant

Amisulpride relationships Subject–Predicate–Object triples

TTTA extracted 121 structured relationships around Amisulpride. Examples in this analysis include Amisulpride → 3D model (JSmol) → Interactive image and Amisulpride → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Amisulpride3D model (JSmol)Interactive image1.00infobox
AmisulprideAHFS/Drugs.comMonograph1.00infobox
AmisulprideATC codeN05AL05 (WHO)1.00infobox
AmisulprideBioavailability48%1.00infobox
AmisulprideCAS Number71675-85-9 Y1.00infobox
AmisulprideChEBICHEBI:64045 Y1.00infobox
AmisulprideChEMBLChEMBL243712 Y1.00infobox
AmisulprideChemSpider2074 Y1.00infobox
AmisulprideCompTox Dashboard (EPA)DTXSID50426131.00infobox
AmisulprideDrug classDopamine D2 and D3 receptor antagonist; Serotonin 5-HT2B and 5-HT7 receptor antagonist; Antipsychotic; Antidepressant; Antiemetic1.00infobox
AmisulprideDrugBankDB06288 Y1.00infobox
AmisulprideECHA InfoCard100.068.9161.00infobox
AmisulprideElimination half-life12 hours1.00infobox
AmisulprideExcretionKidney (23–46%), Faecal1.00infobox
AmisulprideFormulaC17H27N3O4S1.00infobox
AmisulprideIUPHAR/BPS9631.00infobox
AmisulprideKEGGD07310 Y1.00infobox
AmisulprideLegal statusAU: S4 (Prescription only)1.00infobox
AmisulprideLegal statusBR: Class C1 (Other controlled substances)1.00infobox
AmisulprideLegal statusUK: POM (Prescription only)1.00infobox
AmisulprideLegal statusUS: ℞-only1.00infobox
AmisulprideLicense dataUS DailyMed: Amisulpride1.00infobox
AmisulprideLicense dataUS FDA: Barhemsys1.00infobox
AmisulprideMetabolismLiver (minimal; most excreted unchanged)1.00infobox
AmisulprideMolar mass369.48 g·mol−11.00infobox
AmisulprideOther namesAminosultopride; AST; APD-421; APD421; APD-403; APD403; DAN-2163; DAN21631.00infobox
AmisulpridePregnancy categoryAU: C1.00infobox
AmisulprideProtein binding16%1.00infobox
AmisulpridePubChem CID21591.00infobox
AmisulprideRoutes of administrationBy mouth, intravenous1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Amisulpride bring nearby vocabulary together. In this analysis, examples include Treatment, Receptor and D2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Amisulpride
    • Treatment
    • Receptor
    • D2
    • Nausea
    • Vomiting
    • Dopamine
    • Use
    • Approved
    • Schizophrenia
    • United
    • States
    • Found
  • amisulpride
    • Treatment
    • Receptor
    • D2
    • Nausea
    • Vomiting
    • Dopamine
    • Use
    • Approved
    • Schizophrenia
    • United
    • States
    • Found
  • depression
    • Used
    • Development
    • Doses
    • Treat
    • Names
    • Treatment
    • Nausea
    • Serotonin
    • Vomiting
    • Antidepressant
    • Low
    • Postoperative
  • nausea
    • Vomiting
    • Postoperative
    • Subjects
    • Treatment
    • Use
    • Trials
    • Approved
    • Treat
    • United
    • States
    • Used
    • Development
  • vomiting
    • Nausea
    • Postoperative
    • Subjects
    • Treatment
    • Use
    • Trials
    • Approved
    • Depression
    • Treat
    • United
    • States
    • Amisulpride
  • postoperative nausea and vomiting
    • Nausea
    • Vomiting
    • Postoperative
    • United
    • States
    • Subjects
    • Treat
    • Treatment
    • Use
    • Trials
    • Approved
    • Depression
  • dopamine d2 receptor
    • 5-ht7
    • D3
    • Dopamine
    • Nm
    • Antidepressant
    • Receptor
    • Antagonist
    • Schizophrenia
    • Serotonin
    • Presynaptic
    • Sulpiride
    • Dysthymia
  • d3
    • Dopamine
    • Schizophrenia
    • Antagonist
    • Presynaptic
    • Sulpiride
    • Receptor
    • Used
    • Names
    • Serotonin
    • Available
    • Symptoms
    • Also

Connections between topic areas Semantic bridges

For Amisulpride, one of the stronger structural bridges in this analysis connects Amisulpride with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Amisulpride — Overview · splits 123 ⟂ 40
Amisulpride — Adverse effects · splits 135 ⟂ 28
Amisulpride — Pharmacology · splits 137 ⟂ 26
Amisulpride — Medical uses · splits 147 ⟂ 16
Amisulpride — Chemistry · splits 150 ⟂ 13
Amisulpride — Research · splits 152 ⟂ 11
Amisulpride — Society and culture · splits 154 ⟂ 9
Amisulpride — Interactions · splits 156 ⟂ 7
Amisulpride — Contraindications · splits 157 ⟂ 6
Amisulpride — Overdose · splits 159 ⟂ 4

Map overview Semantic statistics

Amisulpride

Nodes163
Edges162
Triples121
Avg. degree1.99
Density0.01227
Components1

Source & methodology

TTTA analyzes the structure around Amisulpride to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Amisulpride · EN edition · Analysis: TopicsToTalkAbout

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