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Sertindole

Sertindole, sold under the brand name Serdolect among others, is an antipsychotic medication. Sertindole was developed by the Danish pharmaceutical company Lundbeck and marketed under license by Abbott Labs. Like other atypical antipsychotics, it has activity at dopamine and serotonin receptors in the brain. It is used in the treatment of schizophrenia.

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
N05AE03 (WHO)
Bioavailability
75%
CAS Number
106516-24-9 Y
ChEBI
CHEBI:9122 Y

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Overview

Medical uses

Adverse effects

Pharmacology

Chemistry

Safety and status

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Map overview Semantic statistics

Sertindole

Nodes42
Edges41
Triples54
Avg. degree1.95
Density0.047619
Components1

How this topic connects Entity context

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Sertindole

Top relations

related to United States · 13
Sertindole → Abbott Labs, April, As, Drug Administration, FDA, In, Lundbeck, Nevertheless, October, QTc, SCoP, Sertindole Cohort Prospective, US Food
related to European Union · 11
Sertindole → As, CHMP, ECG, EMA, EMA's Committee, European Medicines Agency, European Union, Human Use, In, Medicinal Products, September
Legal status · 2
Sertindole → AU: S4 (Prescription only), In general: ℞ (Prescription only)
3D model (JSmol) · 1
Sertindole → Interactive image
AHFS/Drugs.com · 1
Sertindole → International Drug Names
ATC code · 1
Sertindole → N05AE03 (WHO)
Bioavailability · 1
Sertindole → 75%
CAS Number · 1
Sertindole → 106516-24-9 Y
ChEBI · 1
Sertindole → CHEBI:9122 Y
ChEMBL · 1
Sertindole → ChEMBL12713 Y

Important terminology Word statistics

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Important terminology

antipsychotic states adverse effects drugs atypical schizophrenia treatment european union united drug name serdolect others lundbeck status effective 15 increased

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Sertindole3D model (JSmol)Interactive image1.00infobox
SertindoleAHFS/Drugs.comInternational Drug Names1.00infobox
SertindoleATC codeN05AE03 (WHO)1.00infobox
SertindoleBioavailability75%1.00infobox
SertindoleCAS Number106516-24-9 Y1.00infobox
SertindoleChEBICHEBI:9122 Y1.00infobox
SertindoleChEMBLChEMBL12713 Y1.00infobox
SertindoleChemSpider54229 Y1.00infobox
SertindoleCompTox Dashboard (EPA)DTXSID60489671.00infobox
SertindoleDrug classAtypical antipsychotic1.00infobox
SertindoleDrugBankDB06144 Y1.00infobox
SertindoleECHA InfoCard100.162.5621.00infobox
SertindoleElimination half-life3 days1.00infobox
SertindoleExcretionFaecal (the majority), Kidney (4% metabolites; 1% unchanged)1.00infobox
SertindoleFormulaC24H26ClFN4O1.00infobox
SertindoleIUPHAR/BPS981.00infobox
SertindoleKEGGD00561 Y1.00infobox
SertindoleLegal statusAU: S4 (Prescription only)1.00infobox
SertindoleLegal statusIn general: ℞ (Prescription only)1.00infobox
SertindoleMetabolismLiver (mostly via CYP2D6 and CYP3A4)1.00infobox
SertindoleMolar mass440.95 g·mol−11.00infobox
SertindolePregnancy categoryAU: C1.00infobox
SertindoleProtein binding99.5%1.00infobox
SertindolePubChem CID601491.00infobox
SertindoleRoutes of administrationOral1.00infobox
SertindoleTrade namesSerdolect, others1.00infobox
SertindoleUNIIGVV4Z879SP1.00infobox
Sertindoleis apiperidinylindole0.90text

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