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Sertindole: Applications & Companies

Sertindole, sold under the brand name Serdolect among others, is an antipsychotic medication. Sertindole was developed by the Danish pharmaceutical company Lundbeck and marketed under license by Abbott Labs. Like other atypical antipsychotics, it has activity at dopamine and serotonin receptors in the brain. It is used in the treatment of schizophrenia.

Language: English [EN]
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Sertindole topic overview

The analysis highlights Applications and Companies as prominent areas in the source structure around Sertindole.

Related topics
35
Source areas
6
Connected nodes
41
Extracted relationships
54
Concept neighborhoods
16
Bridge connections
41

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Adverse effects · 12 topics
Medical uses · 8 topics
Overview · 7 topics
Safety and status · 5 topics
Chemistry · 2 topics
Pharmacology · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
International Drug Names
ATC code
N05AE03 (WHO)
Bioavailability
75%
CAS Number
106516-24-9 Y
ChEBI
CHEBI:9122 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse effects

Pharmacology

Chemistry

Safety and status

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Sertindole connects Entity context

The extracted context around Sertindole shows recurring relationship patterns in the source. For example, Sertindole → Abbott Labs, April, As, Drug Administration, FDA, In, Lundbeck, Nevertheless, October, QTc, SCoP, Sertindole Cohort Prospective, US Food Another extracted example is Sertindole → As, CHMP, ECG, EMA, EMA's Committee, European Medicines Agency, European Union, Human Use, In, Medicinal Products, September. Use these groups to spot repeated connection types before inspecting the individual relationships.

Sertindole

Top relations

related to United States · 13
Sertindole → Abbott Labs, April, As, Drug Administration, FDA, In, Lundbeck, Nevertheless, October, QTc, SCoP, Sertindole Cohort Prospective, US Food
related to European Union · 11
Sertindole → As, CHMP, ECG, EMA, EMA's Committee, European Medicines Agency, European Union, Human Use, In, Medicinal Products, September
Legal status · 2
Sertindole → AU: S4 (Prescription only), In general: ℞ (Prescription only)
3D model (JSmol) · 1
Sertindole → Interactive image
AHFS/Drugs.com · 1
Sertindole → International Drug Names
ATC code · 1
Sertindole → N05AE03 (WHO)
Bioavailability · 1
Sertindole → 75%
CAS Number · 1
Sertindole → 106516-24-9 Y
ChEBI · 1
Sertindole → CHEBI:9122 Y
ChEMBL · 1
Sertindole → ChEMBL12713 Y

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

antipsychotic states adverse effects drugs atypical schizophrenia treatment european union united drug name serdolect others lundbeck status effective 15 increased

Sertindole relationships Subject–Predicate–Object triples

TTTA extracted 54 structured relationships around Sertindole. Examples in this analysis include Sertindole → 3D model (JSmol) → Interactive image and Sertindole → AHFS/Drugs.com → International Drug Names. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Sertindole3D model (JSmol)Interactive image1.00infobox
SertindoleAHFS/Drugs.comInternational Drug Names1.00infobox
SertindoleATC codeN05AE03 (WHO)1.00infobox
SertindoleBioavailability75%1.00infobox
SertindoleCAS Number106516-24-9 Y1.00infobox
SertindoleChEBICHEBI:9122 Y1.00infobox
SertindoleChEMBLChEMBL12713 Y1.00infobox
SertindoleChemSpider54229 Y1.00infobox
SertindoleCompTox Dashboard (EPA)DTXSID60489671.00infobox
SertindoleDrug classAtypical antipsychotic1.00infobox
SertindoleDrugBankDB06144 Y1.00infobox
SertindoleECHA InfoCard100.162.5621.00infobox
SertindoleElimination half-life3 days1.00infobox
SertindoleExcretionFaecal (the majority), Kidney (4% metabolites; 1% unchanged)1.00infobox
SertindoleFormulaC24H26ClFN4O1.00infobox
SertindoleIUPHAR/BPS981.00infobox
SertindoleKEGGD00561 Y1.00infobox
SertindoleLegal statusAU: S4 (Prescription only)1.00infobox
SertindoleLegal statusIn general: ℞ (Prescription only)1.00infobox
SertindoleMetabolismLiver (mostly via CYP2D6 and CYP3A4)1.00infobox
SertindoleMolar mass440.95 g·mol−11.00infobox
SertindolePregnancy categoryAU: C1.00infobox
SertindoleProtein binding99.5%1.00infobox
SertindolePubChem CID601491.00infobox
SertindoleRoutes of administrationOral1.00infobox
SertindoleTrade namesSerdolect, others1.00infobox
SertindoleUNIIGVV4Z879SP1.00infobox
Sertindoleis apiperidinylindole0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Sertindole bring nearby vocabulary together. In this analysis, examples include Drug, Effective and European. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • antipsychotic
    • Drugs
    • Adverse
    • Effects
    • Found
    • Less
    • Name
    • Others
    • Serdolect
    • Effective
    • Sertindole
    • Status
    • United
  • atypical antipsychotics
    • Atypical
    • Dopamine
    • Serotonin
    • Adverse
    • Effects
    • Quetiapine
    • Slightly
    • Status
    • United
    • Administration
    • Also
    • Approved
  • food and drug administration
    • Administration
    • Drug
    • European
    • Fda
    • States
    • Status
    • Union
    • United
    • Also
    • Approved
    • Labs
    • Name
  • adverse effects
    • Effects
    • Drugs
    • Antipsychotic
    • Atypical
    • Status
    • United
    • Administration
    • Also
    • Antipsychotics
    • Approved
    • Found
    • Less
  • Sertindole
    • Drug
    • Effective
    • European
    • Fda
    • Patients
    • States
    • Union
    • Drugs
    • Administration
    • Also
    • Found
    • Study
  • sertindole
    • Drug
    • Effective
    • European
    • Fda
    • Patients
    • States
    • Union
    • Drugs
    • Administration
    • Also
    • Found
    • Study
  • committee for medicinal products for human use
    • Status
    • United
    • Administration
    • Also
    • Approved
    • Name
    • Others
    • Serdolect
    • Atypical
    • Drug
    • Effective
    • European
  • schizophrenia
    • Effective
    • Treatment
    • Status
    • United
    • Administration
    • Also
    • Approved
    • Serdolect
    • Use
    • Drug
    • European
    • Fda

Connections between topic areas Semantic bridges

For Sertindole, one of the stronger structural bridges in this analysis connects Sertindole with Adverse effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Sertindole — Adverse effects · splits 29 ⟂ 13
Sertindole — Medical uses · splits 33 ⟂ 9
Sertindole — Overview · splits 34 ⟂ 8
Sertindole — Safety and status · splits 36 ⟂ 6
Sertindole — Chemistry · splits 39 ⟂ 3

Map overview Semantic statistics

Sertindole

Nodes42
Edges41
Triples54
Avg. degree1.95
Density0.047619
Components1

Source & methodology

TTTA analyzes the structure around Sertindole to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications & Companies, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Sertindole · EN edition · Analysis: TopicsToTalkAbout

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