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TRAF6

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein mediates the signaling not only from the members of the TNF receptor superfamily, but also from the members of the Toll/IL-1…

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2.3.2.27
Aliases
TRAF6, MGC:3310, RNF85, TNF receptor associated factor 6
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LB4, 1LB5, 1LB6, 2ECI, 2JMD, 3HCS, 3HCT, 3HCU, 4Z8M
Band
11p12 · 2|2 E2
Bgee
secondary oocyte · endothelial cell · gonad · islet of Langerhans · Achilles tendon
BioGPS
More reference expression data

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TRAF6

Nodes42
Edges41
Triples174
Avg. degree1.95
Density0.047619
Components1

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TRAF6

Top relations

Gene ontology · 85
TRAF6 → activation of NF-kappaB-inducing kinase activity, activation of protein kinase activity, animal organ morphogenesis, antigen processing and presentation of exogenous peptide antigen via MHC class II, bone remodeling, bone resorption, CD40 receptor complex, cell cortex, cell development, cellular response to cytokine stimulus, cellular response to DNA damage stimulus, cellular response to lipopolysaccharide, cytokine-mediated signaling pathway, cytoplasm, cytoplasmic side of plasma membrane, cytosol, endosome membrane, Fc-epsilon receptor signaling pathway, histone deacetylase binding, I-kappaB kinase/NF-kappaB signaling
Bgee · 20
TRAF6 → Achilles tendon, ascending aorta, condyle, endothelial cell, fossa, genital tubercle, gonad, granulocyte, Ileal epithelium, islet of Langerhans, lumbar spinal ganglion, lumbar subsegment of spinal cord, middle temporal gyrus, monocyte, popliteal artery, secondary oocyte, tail of embryo, testicle, thymus, ventricular zone
RNA expression pattern · 20
TRAF6 → Achilles tendon, ascending aorta, condyle, endothelial cell, fossa, genital tubercle, gonad, granulocyte, Ileal epithelium, islet of Langerhans, lumbar spinal ganglion, lumbar subsegment of spinal cord, middle temporal gyrus, monocyte, popliteal artery, secondary oocyte, tail of embryo, testicle, thymus, ventricular zone
related to Interactions · 18
TRAF6 → ASK1, CD40, FHL2, HSPB2, IKBKG, IRAK1, IRAK2, MAP3K7IP2, MAP3K7PPP4C, RANK, SDCBP, Sequestosome, SIGIRR, TAB1, TAX1BP1, TNFAIP3, TNFRSF13B, UBE2N
related to External links · 3
TRAF6 → Medicine Medical Subject Headings, MeSH, National Library
Band · 2
TRAF6 → 11p12, 2|2 E2
Chr. · 2
TRAF6 → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
TRAF6 → 101,532,014 bp, 36,510,272 bp
2.3.2.27 · 1
TRAF6 → ↗
Aliases · 1
TRAF6 → TRAF6, MGC:3310, RNF85, TNF receptor associated factor 6

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Important terminology

protein human bp chr band receptor chromosome 11 gene tnf location traf cd40 factor mouse associated signaling signal function external

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
TRAF62.3.2.271.00infobox
TRAF6AliasesTRAF6, MGC:3310, RNF85, TNF receptor associated factor 61.00infobox
TRAF6Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1LB4, 1LB5, 1LB6, 2ECI, 2JMD, 3HCS, 3HCT, 3HCU, 4Z8M1.00infobox
TRAF6Band11p121.00infobox
TRAF6Band2|2 E21.00infobox
TRAF6Bgeesecondary oocyte1.00infobox
TRAF6Bgeeendothelial cell1.00infobox
TRAF6Bgeegonad1.00infobox
TRAF6Bgeeislet of Langerhans1.00infobox
TRAF6BgeeAchilles tendon1.00infobox
TRAF6Bgeemiddle temporal gyrus1.00infobox
TRAF6Bgeetesticle1.00infobox
TRAF6Bgeeascending aorta1.00infobox
TRAF6Bgeemonocyte1.00infobox
TRAF6Bgeepopliteal artery1.00infobox
TRAF6BgeeIleal epithelium1.00infobox
TRAF6Bgeegenital tubercle1.00infobox
TRAF6Bgeetail of embryo1.00infobox
TRAF6Bgeelumbar subsegment of spinal cord1.00infobox
TRAF6Bgeelumbar spinal ganglion1.00infobox
TRAF6Bgeegranulocyte1.00infobox
TRAF6Bgeethymus1.00infobox
TRAF6Bgeeventricular zone1.00infobox
TRAF6Bgeecondyle1.00infobox
TRAF6Bgeefossa1.00infobox
TRAF6BioGPSMore reference expression data1.00infobox
TRAF6Chr.Chromosome 11 (human)1.00infobox
TRAF6Chr.Chromosome 2 (mouse)1.00infobox
TRAF6DatabasesNCBI: entry; OMA: entry1.00infobox
TRAF6End36,510,272 bp1.00infobox

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