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Stimulator of interferon genes

Stimulator of interferon genes (STING), also known as transmembrane protein 173 (TMEM173) and MPYS/MITA/ERIS is a regulator protein that in humans is encoded by the STING1 gene.

Function, STING signaling mechanisms & Expression

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Aliases
STING1, ERIS, MITA, MPYS, NET23, SAVI, STING, hMITA, hSTING, Stimulator of interferon genes, transmembrane protein 173, STING-beta, TMEM173, stimulator of interferon response cG…
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4EF4, 4EF5, 4EMT, 4EMU, 4F5D, 4F5E, 4F5W, 4F5Y, 4F9E, 4F9G, 4KSY, 4LOH, 4LOI, 4QXO, 4QXP, 4QXQ, 4QXR, 5BQX,…
Band
5q31.2 · 18 B2|18
Bgee
right uterine tube · olfactory zone of nasal mucosa · granulocyte · gastric mucosa · right coronary artery
BioGPS
n/a
Chr.
Chromosome 5 (human) · Chromosome 18 (mouse)

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Overview

Structure

Expression

Localization

Function

STING signaling mechanisms

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Map overview Semantic statistics

Stimulator of interferon genes

Nodes82
Edges81
Triples106
Avg. degree1.98
Density0.02439
Components1

How this topic connects Entity context

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Stimulator of interferon genes

Top relations

Gene ontology · 43
Stimulator of interferon genes → 2',3'-cyclic GMP-AMP binding, activation of innate immune response, apoptotic process, cellular response to exogenous dsRNA, cellular response to interferon-beta, cellular response to organic cyclic compound, cyclic-di-GMP binding, cytoplasm, cytoplasmic pattern recognition receptor signaling pathway in response to virus, cytoplasmic vesicle membrane, defense response to virus, endoplasmic reticulum, endoplasmic reticulum membrane, Golgi apparatus, identical protein binding, immune system process, innate immune response, integral component of membrane, interferon-beta production, membrane
Bgee · 20
Stimulator of interferon genes → apex of heart, ascending aorta, blood, cervix, Descending thoracic aorta, endothelial cell of lymphatic vessel, gastric mucosa, granulocyte, internal carotid artery, interventricular septum, left uterine tube, lumbar spinal ganglion, mesenteric lymph nodes, olfactory zone of nasal mucosa, right coronary artery, right uterine tube, spleen, tail of embryo, thymus, upper lobe of left lung
RNA expression pattern · 20
Stimulator of interferon genes → apex of heart, ascending aorta, blood, cervix, Descending thoracic aorta, endothelial cell of lymphatic vessel, gastric mucosa, granulocyte, internal carotid artery, interventricular septum, left uterine tube, lumbar spinal ganglion, mesenteric lymph nodes, olfactory zone of nasal mucosa, right coronary artery, right uterine tube, spleen, tail of embryo, thymus, upper lobe of left lung
Band · 2
Stimulator of interferon genes → 18 B2|18, 5q31.2
Chr. · 2
Stimulator of interferon genes → Chromosome 18 (mouse), Chromosome 5 (human)
End · 2
Stimulator of interferon genes → 139,482,935 bp, 35,873,607 bp
Aliases · 1
Stimulator of interferon genes → STING1, ERIS, MITA, MPYS, NET23, SAVI, STING, hMITA, hSTING, Stimulator of interferon genes, transmembrane protein 173, STING-beta, TMEM173, stimulator of interferon response cG…
Available structures · 1
Stimulator of interferon genes → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4EF4, 4EF5, 4EMT, 4EMU, 4F5D, 4F5E, 4F5W, 4F5Y, 4F9E, 4F9G, 4KSY, 4LOH, 4LOI, 4QXO, 4QXP, 4QXQ, 4QXR, 5BQX,…
BioGPS · 1
Stimulator of interferon genes → n/a
Databases · 1
Stimulator of interferon genes → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

sting interferon type response dna intracellular infection protein immune signaling shown cells production innate human bp role host infected also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Stimulator of interferon genesAliasesSTING1, ERIS, MITA, MPYS, NET23, SAVI, STING, hMITA, hSTING, Stimulator of interferon genes, transmembrane protein 173, STING-beta, TMEM173, stimulator of interferon response cG…1.00infobox
Stimulator of interferon genesAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4EF4, 4EF5, 4EMT, 4EMU, 4F5D, 4F5E, 4F5W, 4F5Y, 4F9E, 4F9G, 4KSY, 4LOH, 4LOI, 4QXO, 4QXP, 4QXQ, 4QXR, 5BQX,…1.00infobox
Stimulator of interferon genesBand5q31.21.00infobox
Stimulator of interferon genesBand18 B2|181.00infobox
Stimulator of interferon genesBgeeright uterine tube1.00infobox
Stimulator of interferon genesBgeeolfactory zone of nasal mucosa1.00infobox
Stimulator of interferon genesBgeegranulocyte1.00infobox
Stimulator of interferon genesBgeegastric mucosa1.00infobox
Stimulator of interferon genesBgeeright coronary artery1.00infobox
Stimulator of interferon genesBgeeupper lobe of left lung1.00infobox
Stimulator of interferon genesBgeeDescending thoracic aorta1.00infobox
Stimulator of interferon genesBgeeleft uterine tube1.00infobox
Stimulator of interferon genesBgeeapex of heart1.00infobox
Stimulator of interferon genesBgeeascending aorta1.00infobox
Stimulator of interferon genesBgeelumbar spinal ganglion1.00infobox
Stimulator of interferon genesBgeemesenteric lymph nodes1.00infobox
Stimulator of interferon genesBgeeendothelial cell of lymphatic vessel1.00infobox
Stimulator of interferon genesBgeeinterventricular septum1.00infobox
Stimulator of interferon genesBgeespleen1.00infobox
Stimulator of interferon genesBgeetail of embryo1.00infobox
Stimulator of interferon genesBgeeblood1.00infobox
Stimulator of interferon genesBgeethymus1.00infobox
Stimulator of interferon genesBgeecervix1.00infobox
Stimulator of interferon genesBgeeinternal carotid artery1.00infobox
Stimulator of interferon genesBioGPSn/a1.00infobox
Stimulator of interferon genesChr.Chromosome 5 (human)1.00infobox
Stimulator of interferon genesChr.Chromosome 18 (mouse)1.00infobox
Stimulator of interferon genesDatabasesNCBI: entry; OMA: entry1.00infobox
Stimulator of interferon genesEnd139,482,935 bp1.00infobox
Stimulator of interferon genesEnd35,873,607 bp1.00infobox

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