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CCL7

Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-chemotactic protein 3 (MCP3). CCL7 is a small protein that belongs to the CC chemokine family and is most closely related to CCL2 (previously called MCP1).

Regions, Clinical importance & Genomics

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Clinical importance

6 related topics

Genomics

5 related topics

Function

4 related topics

Molecular biology

1 related topics

Key facts & relationships

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Aliases
CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, C-C motif chemokine ligand 7
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1BO0, 1NCV, 4ZKC
Band
17q12
Bgee
islet of Langerhans · mucosa of urinary bladder · stromal cell of endometrium · amniotic fluid · cartilage tissue
BioGPS
More reference expression data
Chr.
Chromosome 17 (human)

Topics to explore

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Overview

Genomics

Molecular biology

Function

Clinical importance

Advanced semantic analysis

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Map overview Semantic statistics

CCL7

Nodes26
Edges25
Triples110
Avg. degree1.92
Density0.076923
Components1

How this topic connects Entity context

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CCL7

Top relations

Gene ontology · 33
CCL7 → CCR chemokine receptor binding, CCR1 chemokine receptor binding, CCR2 chemokine receptor binding, cell-cell signaling, cellular calcium ion homeostasis, cellular response to ethanol, cellular response to interferon-gamma, cellular response to interleukin-1, cellular response to tumor necrosis factor, chemokine activity, chemokine-mediated signaling pathway, chemotaxis, cytokine activity, cytoskeleton organization, eosinophil chemotaxis, extracellular region, extracellular space, G protein-coupled receptor signaling pathway, heparin binding, immune response
related to Clinical importance · 14
CCL7 → CCL7-mediated, CCR2, Diseases, Early, For, Furthermore, HIV, Listeria, Next, The, TipDCs, TLR9, TNF/iNOS-producing, West Nile Virus
Bgee · 10
CCL7 → amniotic fluid, appendix, cartilage tissue, islet of Langerhans, lower lobe of lung, mucosa of urinary bladder, parietal pleura, rectum, smooth muscle tissue, stromal cell of endometrium
RNA expression pattern · 10
CCL7 → amniotic fluid, appendix, cartilage tissue, islet of Langerhans, lower lobe of lung, mucosa of urinary bladder, parietal pleura, rectum, smooth muscle tissue, stromal cell of endometrium
related to Genomics · 10
CCL7 → AU-rich, C-terminal, CC, In, MCP, SCYA7, The, The CCL7, This, UTR
related to Function · 8
CCL7 → Ca2, CXC, DCs, Furthermore, It, NK, The, Thus
related to Molecular biology · 3
CCL7 → COS, In, The
related to External links · 2
CCL7 → Human CCL7, UCSC Genome Browser
Aliases · 1
CCL7 → CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, C-C motif chemokine ligand 7
Available structures · 1
CCL7 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1BO0, 1NCV, 4ZKC

Important terminology Word statistics

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Important terminology

chemokine gene protein human immune cells chromosome signal 17 bp leukocytes also ccr2 region response chr molecular amino acids monocytes

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CCL7AliasesCCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, C-C motif chemokine ligand 71.00infobox
CCL7Available structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes1BO0, 1NCV, 4ZKC1.00infobox
CCL7Band17q121.00infobox
CCL7Bgeeislet of Langerhans1.00infobox
CCL7Bgeemucosa of urinary bladder1.00infobox
CCL7Bgeestromal cell of endometrium1.00infobox
CCL7Bgeeamniotic fluid1.00infobox
CCL7Bgeecartilage tissue1.00infobox
CCL7Bgeeappendix1.00infobox
CCL7Bgeerectum1.00infobox
CCL7Bgeesmooth muscle tissue1.00infobox
CCL7Bgeelower lobe of lung1.00infobox
CCL7Bgeeparietal pleura1.00infobox
CCL7BioGPSMore reference expression data1.00infobox
CCL7Chr.Chromosome 17 (human)1.00infobox
CCL7DatabasesNCBI: entry; OMA: entry1.00infobox
CCL7End34,272,242 bp1.00infobox
CCL7EnsemblENSG000001086881.00infobox
CCL7Entrez63541.00infobox
CCL7External IDsOMIM: 158106; GeneCards: CCL71.00infobox
CCL7Gene location (Human)Gene location (Human)Chr.Chromosome 17 (human)Band17q12Start34,270,221 bpEnd34,272,242 bp1.00infobox
CCL7Gene ontologycytokine activity1.00infobox
CCL7Gene ontologyheparin binding1.00infobox
CCL7Gene ontologychemokine activity1.00infobox
CCL7Gene ontologyCCR1 chemokine receptor binding1.00infobox
CCL7Gene ontologyprotein binding1.00infobox
CCL7Gene ontologyCCR2 chemokine receptor binding1.00infobox
CCL7Gene ontologyCCR chemokine receptor binding1.00infobox
CCL7Gene ontologyextracellular region1.00infobox
CCL7Gene ontologyextracellular space1.00infobox

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