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IFI16

Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene.

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11 related topics

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2 related topics

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Aliases
IFI16, IFNGIP1, PYHIN2, interferon gamma inducible protein 16
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2OQ0, 3B6Y, 3RLN, 3RLO, 3RNU, 4QGU
Band
1q23.1 · 1|1 H3
Bgee
germinal epithelium · pericardium · palpebral conjunctiva · Achilles tendon · lymph node
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

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Map overview Semantic statistics

IFI16

Nodes16
Edges15
Triples124
Avg. degree1.88
Density0.125
Components1

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IFI16

Top relations

Gene ontology · 46
IFI16 → activation of cysteine-type endopeptidase activity, activation of innate immune response, apoptotic process, autophagy, cell population proliferation, cellular response to glucose starvation, cellular response to interferon-beta, cellular response to ionizing radiation, cytoplasm, cytosol, defense response to virus, DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, double-stranded DNA binding, hemopoiesis, identical protein binding, immune system process, inflammatory response, innate immune response, intrinsic apoptotic signaling pathway by p53 class mediator
Bgee · 19
IFI16 → Achilles tendon, blood, bone marrow, germinal epithelium, granulocyte, human penis, lumbar spinal ganglion, lymph node, mesenteric lymph nodes, mucosa of nose, palpebral conjunctiva, pericardium, spleen, stroma of bone marrow, subcutaneous adipose tissue, superficial temporal artery, thymus, vena cava, white adipose tissue
RNA expression pattern · 19
IFI16 → Achilles tendon, blood, bone marrow, germinal epithelium, granulocyte, human penis, lumbar spinal ganglion, lymph node, mesenteric lymph nodes, mucosa of nose, palpebral conjunctiva, pericardium, spleen, stroma of bone marrow, subcutaneous adipose tissue, superficial temporal artery, thymus, vena cava, white adipose tissue
related to Function · 11
IFI16 → CD4, DAMP, DNA, HIN-200, HIV-infected, It, Ras/Raf, Recently, The, This, TLR4
related to External links · 6
IFI16 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
Band · 2
IFI16 → 1q23.1, 1|1 H3
Chr. · 2
IFI16 → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
IFI16 → 159,055,155 bp, 173,426,840 bp
Aliases · 1
IFI16 → IFI16, IFNGIP1, PYHIN2, interferon gamma inducible protein 16
Available structures · 1
IFI16 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2OQ0, 3B6Y, 3RLN, 3RLO, 3RNU, 4QGU

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Important terminology

bp protein human gene chr band chromosome location function dna p53 uniprot mouse binding cell myeloid differentiation external nucleoplasm also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
IFI16AliasesIFI16, IFNGIP1, PYHIN2, interferon gamma inducible protein 161.00infobox
IFI16Available structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes2OQ0, 3B6Y, 3RLN, 3RLO, 3RNU, 4QGU1.00infobox
IFI16Band1q23.11.00infobox
IFI16Band1|1 H31.00infobox
IFI16Bgeegerminal epithelium1.00infobox
IFI16Bgeepericardium1.00infobox
IFI16Bgeepalpebral conjunctiva1.00infobox
IFI16BgeeAchilles tendon1.00infobox
IFI16Bgeelymph node1.00infobox
IFI16Bgeesuperficial temporal artery1.00infobox
IFI16Bgeevena cava1.00infobox
IFI16Bgeemucosa of nose1.00infobox
IFI16Bgeespleen1.00infobox
IFI16Bgeehuman penis1.00infobox
IFI16Bgeemesenteric lymph nodes1.00infobox
IFI16Bgeesubcutaneous adipose tissue1.00infobox
IFI16Bgeethymus1.00infobox
IFI16Bgeebone marrow1.00infobox
IFI16Bgeewhite adipose tissue1.00infobox
IFI16Bgeeblood1.00infobox
IFI16Bgeegranulocyte1.00infobox
IFI16Bgeelumbar spinal ganglion1.00infobox
IFI16Bgeestroma of bone marrow1.00infobox
IFI16BioGPSMore reference expression data1.00infobox
IFI16Chr.Chromosome 1 (human)1.00infobox
IFI16Chr.Chromosome 1 (mouse)1.00infobox
IFI16DatabasesNCBI: entry; OMA: entry1.00infobox
IFI16End159,055,155 bp1.00infobox
IFI16End173,426,840 bp1.00infobox
IFI16EnsemblENSG000001635651.00infobox

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