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MAP1LC3A: Standards, Regulation & Function

Microtubule-associated proteins 1A/1B light chain 3A is a protein that in humans is encoded by the MAP1LC3A gene. Two transcript variants encoding different isoforms have been found for this gene.

Language: English [EN]
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MAP1LC3A topic overview

The analysis highlights Standards, Regulation and Function as prominent areas in the source structure around MAP1LC3A.

Related topics
15
Source areas
3
Connected nodes
18
Extracted relationships
99
Concept neighborhoods
12
Bridge connections
18

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Regulation · 7 topics
Function · 6 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule associated protein 1 light chain 3 alpha
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ECI, 3WAL, 3WAN, 4ZDV
Band
20q11.22 · 2|2 H1
Bgee
right hemisphere of cerebellum · right frontal lobe · Brodmann area 9 · cingulate gyrus · anterior cingulate cortex
BioGPS
n/a
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Regulation

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How MAP1LC3A connects Entity context

The extracted context around MAP1LC3A shows recurring relationship patterns in the source. For example, MAP1LC3A → autolysosome, autophagosome, autophagosome assembly, autophagosome maturation, autophagosome membrane, autophagy, autophagy of mitochondrion, cellular response to amino acid starvation, cellular response to copper ion, cellular response to hydrogen peroxide, cellular response to nitrogen starvation, cellular response to starvation, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytosol, endomembrane system, late endosome, macroautophagy, membrane Another extracted example is MAP1LC3A → amygdala, anterior cingulate cortex, anterior pituitary, Brodmann area 9, C1 segment, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, digastric muscle, dorsomedial hypothalamic nucleus, hypothalamus, lip, muscle of thigh, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, right ventricle, seminiferous tubule, superior frontal gyrus, triceps brachii muscle. Use these groups to spot repeated connection types before inspecting the individual relationships.

MAP1LC3A

Top relations

Gene ontology · 32
MAP1LC3A → autolysosome, autophagosome, autophagosome assembly, autophagosome maturation, autophagosome membrane, autophagy, autophagy of mitochondrion, cellular response to amino acid starvation, cellular response to copper ion, cellular response to hydrogen peroxide, cellular response to nitrogen starvation, cellular response to starvation, cytoplasm, cytoplasmic vesicle, cytoskeleton, cytosol, endomembrane system, late endosome, macroautophagy, membrane
Bgee · 20
MAP1LC3A → amygdala, anterior cingulate cortex, anterior pituitary, Brodmann area 9, C1 segment, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, digastric muscle, dorsomedial hypothalamic nucleus, hypothalamus, lip, muscle of thigh, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, right ventricle, seminiferous tubule, superior frontal gyrus, triceps brachii muscle
RNA expression pattern · 20
MAP1LC3A → amygdala, anterior cingulate cortex, anterior pituitary, Brodmann area 9, C1 segment, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, digastric muscle, dorsomedial hypothalamic nucleus, hypothalamus, lip, muscle of thigh, prefrontal cortex, primary visual cortex, right frontal lobe, right hemisphere of cerebellum, right ventricle, seminiferous tubule, superior frontal gyrus, triceps brachii muscle
related to Regulation · 4
MAP1LC3A → C-terminus, For, Noncovalent, These
Band · 2
MAP1LC3A → 20q11.22, 2|2 H1
Chr. · 2
MAP1LC3A → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
MAP1LC3A → 155,119,993 bp, 34,560,345 bp
Aliases · 1
MAP1LC3A → MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule associated protein 1 light chain 3 alpha
Available structures · 1
MAP1LC3A → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ECI, 3WAL, 3WAN, 4ZDV
BioGPS · 1
MAP1LC3A → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene bp chr protein human band chromosome 20 autophagy light chain location map1a map1b microtubule mouse function cytoskeleton microtubule-associated proteins

MAP1LC3A relationships Subject–Predicate–Object triples

TTTA extracted 99 structured relationships around MAP1LC3A. Examples in this analysis include MAP1LC3A → Aliases → MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule associated protein 1 light chain 3 alpha and MAP1LC3A → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ECI, 3WAL, 3WAN, 4ZDV. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MAP1LC3AAliasesMAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule associated protein 1 light chain 3 alpha1.00infobox
MAP1LC3AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3ECI, 3WAL, 3WAN, 4ZDV1.00infobox
MAP1LC3ABand20q11.221.00infobox
MAP1LC3ABand2|2 H11.00infobox
MAP1LC3ABgeeright hemisphere of cerebellum1.00infobox
MAP1LC3ABgeeright frontal lobe1.00infobox
MAP1LC3ABgeeBrodmann area 91.00infobox
MAP1LC3ABgeecingulate gyrus1.00infobox
MAP1LC3ABgeeanterior cingulate cortex1.00infobox
MAP1LC3ABgeeprefrontal cortex1.00infobox
MAP1LC3ABgeehypothalamus1.00infobox
MAP1LC3ABgeeC1 segment1.00infobox
MAP1LC3ABgeeamygdala1.00infobox
MAP1LC3ABgeeanterior pituitary1.00infobox
MAP1LC3ABgeelip1.00infobox
MAP1LC3ABgeemuscle of thigh1.00infobox
MAP1LC3ABgeeright ventricle1.00infobox
MAP1LC3ABgeedentate gyrus of hippocampal formation granule cell1.00infobox
MAP1LC3ABgeesuperior frontal gyrus1.00infobox
MAP1LC3ABgeeprimary visual cortex1.00infobox
MAP1LC3ABgeeseminiferous tubule1.00infobox
MAP1LC3ABgeedorsomedial hypothalamic nucleus1.00infobox
MAP1LC3ABgeedigastric muscle1.00infobox
MAP1LC3ABgeetriceps brachii muscle1.00infobox
MAP1LC3ABioGPSn/a1.00infobox
MAP1LC3AChr.Chromosome 20 (human)1.00infobox
MAP1LC3AChr.Chromosome 2 (mouse)1.00infobox
MAP1LC3ADatabasesNCBI: entry; OMA: entry1.00infobox
MAP1LC3AEnd34,560,345 bp1.00infobox
MAP1LC3AEnd155,119,993 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around MAP1LC3A bring nearby vocabulary together. In this analysis, examples include Function, Microtubule and Microtubule-associated. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • gene
    • Protein
    • Location
    • Chromosome
    • Human
    • Light
    • Map1lc3a
    • Bp
    • Chr
    • End
    • Function
    • Microtubule
    • Microtubule-associated
  • autophagy
    • Functions
    • Important
    • Interactions
    • Phosphatidylethanolamine
    • Protein
    • Cytoskeleton
    • End
    • Function
    • Microtubule
    • Microtubule-associated
    • Mouse
    • One
  • function
    • Microtubule
    • Search
    • Location
    • Chromosome
    • Cytoskeleton
    • Human
    • Map1lc3a
    • Bp
    • Chr
    • Protein
    • End
    • Gene
  • MAP1LC3A
    • Function
    • Microtubule
    • Microtubule-associated
    • Protein
    • Proteins
    • Search
    • Gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • map1lc3a
    • Function
    • Microtubule
    • Microtubule-associated
    • Protein
    • Proteins
    • Search
    • Gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
  • protein
    • Function
    • Microtubule
    • Phosphatidylethanolamine
    • Proteins
    • Search
    • Location
    • Map1a
    • Map1b
    • Autophagy
    • Chromosome
    • Human
    • Bp
  • protein kinase a
    • Function
    • Microtubule
    • Phosphatidylethanolamine
    • Proteins
    • Search
    • Location
    • Map1a
    • Map1b
    • Autophagy
    • Chromosome
    • Human
    • Bp
  • cytoskeleton
    • End
    • Function
    • Interactions
    • Microtubule
    • Microtubule-associated
    • Mouse
    • Phosphatidylethanolamine
    • Proteins
    • Search
    • Location
    • Map1a
    • Map1b

Connections between topic areas Semantic bridges

For MAP1LC3A, one of the stronger structural bridges in this analysis connects MAP1LC3A with Regulation. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MAP1LC3ARegulation · splits 11 ⟂ 8
MAP1LC3AFunction · splits 12 ⟂ 7
MAP1LC3AOverview · splits 16 ⟂ 3

Map overview Semantic statistics

MAP1LC3A

Nodes19
Edges18
Triples99
Avg. degree1.89
Density0.105263
Components1

Source & methodology

TTTA analyzes the structure around MAP1LC3A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Standards, Regulation & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MAP1LC3A · EN edition · Analysis: TopicsToTalkAbout

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