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Eomesodermin: Nervous system development, Cardiac development & Immune response

Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that in humans is encoded by the EOMES gene.

Language: English [EN]
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Eomesodermin topic overview

The analysis highlights Nervous system development, Cardiac development and Immune response as prominent areas in the source structure around Eomesodermin.

Related topics
56
Source areas
4
Connected nodes
60
Extracted relationships
128
Concept neighborhoods
24
Bridge connections
60

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Nervous system development · 34 topics
Cardiac development · 8 topics
Overview · 8 topics
Immune response · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
EOMES, TBR2, Eomesodermin
Band
3p24.1 · 9 70.21 cM|9 F3
Bgee
ganglionic eminence · ventricular zone · granulocyte · cerebellar vermis · cerebellar hemisphere
BioGPS
n/a
Chr.
Chromosome 3 (human) · Chromosome 9 (mouse)
Databases
NCBI: entry; OMA: entry

Suggested research paths

A focused starting point derived from the topic graph, ranked independently of the source article order.

Start with these areas

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Nervous system development

Cardiac development

Immune response

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Eomesodermin connects Entity context

The extracted context around Eomesodermin shows recurring relationship patterns in the source. For example, Eomesodermin → adaptive immune response, anatomical structure morphogenesis, blastocyst development, brain development, cardioblast differentiation, CD8-positive, alpha-beta T cell differentiation involved in immune response, cell differentiation, cell differentiation involved in embryonic placenta development, cerebral cortex neuron differentiation, cerebral cortex regionalization, chromatin binding, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, endoderm development, endoderm formation, endodermal cell fate specification, gastrulation, immune system process, intracellular anatomical structure Another extracted example is Eomesodermin → blastocyst, blood, cerebellar hemisphere, cerebellar vermis, embryo, epiblast, ganglionic eminence, granulocyte, lymph node, mesoderm, olfactory bulb, right hemisphere of cerebellum, spleen, testicle, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Eomesodermin

Top relations

Gene ontology · 44
Eomesodermin → adaptive immune response, anatomical structure morphogenesis, blastocyst development, brain development, cardioblast differentiation, CD8-positive, alpha-beta T cell differentiation involved in immune response, cell differentiation, cell differentiation involved in embryonic placenta development, cerebral cortex neuron differentiation, cerebral cortex regionalization, chromatin binding, DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, endoderm development, endoderm formation, endodermal cell fate specification, gastrulation, immune system process, intracellular anatomical structure
Bgee · 15
Eomesodermin → blastocyst, blood, cerebellar hemisphere, cerebellar vermis, embryo, epiblast, ganglionic eminence, granulocyte, lymph node, mesoderm, olfactory bulb, right hemisphere of cerebellum, spleen, testicle, ventricular zone
RNA expression pattern · 15
Eomesodermin → blastocyst, blood, cerebellar hemisphere, cerebellar vermis, embryo, epiblast, ganglionic eminence, granulocyte, lymph node, mesoderm, olfactory bulb, right hemisphere of cerebellum, spleen, testicle, ventricular zone
related to Neurogenesis · 14
Eomesodermin → During, Eomesodermin/Tbr2, IPC, NeuroD, Neurogenin-2, Neurons, Pax6, Radial, Similar, Tbr1, Tbr2, The IPCs, These, This
related to Cardiac development · 9
Eomesodermin → Early, Eomesodermin/Tbr2, Lack, Mef2c, Mesp1, Myl2, Myl7, Myocardin, Nkx2
related to Role in adult development · 7
Eomesodermin → Another, Eomesodermin/Tbr2, Eomesodermin/Tbr2's, It, Sox2, The, There
related to Immune response · 4
Eomesodermin → CD4, CD8, Eomesodermin/Tbr2, Lack
Band · 2
Eomesodermin → 3p24.1, 9 70.21 cM|9 F3
Chr. · 2
Eomesodermin → Chromosome 3 (human), Chromosome 9 (mouse)
End · 2
Eomesodermin → 118,315,200 bp, 27,722,711 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

tbr2 cells brain gene neurogenesis radial glia bp also t-box development eomes chr human band protein neurons mice zone involved

Eomesodermin relationships Subject–Predicate–Object triples

TTTA extracted 128 structured relationships around Eomesodermin. Examples in this analysis include Eomesodermin → Aliases → EOMES, TBR2, Eomesodermin and Eomesodermin → Band → 3p24.1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EomesoderminAliasesEOMES, TBR2, Eomesodermin1.00infobox
EomesoderminBand3p24.11.00infobox
EomesoderminBand9 70.21 cM|9 F31.00infobox
EomesoderminBgeeganglionic eminence1.00infobox
EomesoderminBgeeventricular zone1.00infobox
EomesoderminBgeegranulocyte1.00infobox
EomesoderminBgeecerebellar vermis1.00infobox
EomesoderminBgeecerebellar hemisphere1.00infobox
EomesoderminBgeetesticle1.00infobox
EomesoderminBgeeright hemisphere of cerebellum1.00infobox
EomesoderminBgeelymph node1.00infobox
EomesoderminBgeeblood1.00infobox
EomesoderminBgeespleen1.00infobox
EomesoderminBgeeolfactory bulb1.00infobox
EomesoderminBgeeepiblast1.00infobox
EomesoderminBgeeblastocyst1.00infobox
EomesoderminBgeeembryo1.00infobox
EomesoderminBgeemesoderm1.00infobox
EomesoderminBioGPSn/a1.00infobox
EomesoderminChr.Chromosome 3 (human)1.00infobox
EomesoderminChr.Chromosome 9 (mouse)1.00infobox
EomesoderminDatabasesNCBI: entry; OMA: entry1.00infobox
EomesoderminEnd27,722,711 bp1.00infobox
EomesoderminEnd118,315,200 bp1.00infobox
EomesoderminEnsemblENSG000001635081.00infobox
EomesoderminEntrez83201.00infobox
EomesoderminExternal IDsOMIM: 604615; MGI: 1201683; GeneCards: EOMES1.00infobox
EomesoderminGene location (Human)Gene location (Human)Chr.Chromosome 3 (human)Band3p24.1Start27,715,949 bpEnd27,722,711 bp1.00infobox
EomesoderminGene location (Mouse)Gene location (Mouse)Chr.Chromosome 9 (mouse)Band9 70.21 cM|9 F3Start118,307,280 bpEnd118,315,200 bp1.00infobox
EomesoderminGene ontologyRNA polymerase II transcription regulatory region sequence-specific DNA binding1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Eomesodermin bring nearby vocabulary together. In this analysis, examples include Tbr2, Mice and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Eomesodermin
    • Tbr2
    • Mice
    • Cells
    • Found
    • Lacking
    • Development
    • Brain
    • Eomes
    • Protein
    • Role
    • Cd8
    • Involved
  • eomesodermin
    • Tbr2
    • Mice
    • Cells
    • Found
    • Lacking
    • Development
    • Brain
    • Eomes
    • Protein
    • Role
    • Cd8
    • Involved
  • protein
    • Gene
    • T-box
    • Neuron
    • Cortex
    • Expressed
    • Expression
    • Immune
    • Location
    • Regulation
    • Response
    • Tbr2
    • Band
  • gene
    • Location
    • Chromosome
    • Human
    • Protein
    • T-box
    • Bp
    • Chr
    • Expression
    • Immune
    • Regulation
    • Response
    • Band
  • conserved protein family
    • Gene
    • T-box
    • Neuron
    • Cortex
    • Expressed
    • Expression
    • Immune
    • Location
    • Regulation
    • Response
    • Tbr2
    • Band
  • gene expression
    • Location
    • Regulation
    • Chromosome
    • Human
    • Protein
    • T-box
    • Transcription
    • Bp
    • Chr
    • Involved
    • Expression
    • Gene
  • brain
    • Ventricular
    • Zone
    • Involved
    • Mice
    • Glia
    • Radial
    • Cortex
    • Eomes
    • Protein
    • Eomesodermin
    • Lacking
    • Tbr2
  • sub ventricular zone
    • Ventricular
    • Zone
    • Brain
    • Involved
    • Lacking
    • Neuron
    • Development
    • Mice
    • Neurogenesis
    • Cells
    • Intermediate
    • Transcription

Connections between topic areas Semantic bridges

For Eomesodermin, one of the stronger structural bridges in this analysis connects Eomesodermin with Nervous system development. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EomesoderminNervous system development · splits 26 ⟂ 35
EomesoderminOverview · splits 52 ⟂ 9
EomesoderminCardiac development · splits 52 ⟂ 9
EomesoderminImmune response · splits 54 ⟂ 7

Map overview Semantic statistics

Eomesodermin

Nodes61
Edges60
Triples128
Avg. degree1.97
Density0.032787
Components1

Source & methodology

TTTA analyzes the structure around Eomesodermin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Nervous system development, Cardiac development & Immune response, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Eomesodermin · EN edition · Analysis: TopicsToTalkAbout

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