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Interleukin-7 receptor-α: Measurement & Overview

Interleukin-7 receptor subunit alpha (IL7R-α) also known as CD127 (Cluster of Differentiation 127) is a protein that in humans is encoded by the IL7R gene.

Language: English [EN]
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Interleukin-7 receptor-α topic overview

The analysis highlights Measurement and Overview as prominent areas in the source structure around Interleukin-7 receptor-α.

Related topics
6
Source areas
1
Connected nodes
7
Extracted relationships
88
Concept neighborhoods
8
Bridge connections
7

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 6 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP1
Band
5p13.2 · 15 A1|15 4.16 cM
Bgee
right lung · granulocyte · lymph node · lower lobe of lung · epithelium of nasopharynx
BioGPS
More reference expression data
Chr.
Chromosome 5 (human) · Chromosome 15 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Interleukin-7 receptor-α connects Entity context

The extracted context around Interleukin-7 receptor-α shows recurring relationship patterns in the source. For example, Interleukin-7 receptor-α → antigen binding, B cell proliferation, cell morphogenesis, cell surface receptor signaling pathway, clathrin-coated vesicle membrane, cytokine receptor activity, external side of plasma membrane, extracellular region, homeostasis of number of cells, immune response, immunoglobulin production, integral component of membrane, interleukin-7 receptor activity, interleukin-7-mediated signaling pathway, lymph node development, membrane, membrane organization, negative regulation of T cell apoptotic process, negative regulation of T cell mediated cytotoxicity, plasma membrane Another extracted example is Interleukin-7 receptor-α → appendix, blood, bone marrow, epithelium of nasopharynx, gallbladder, granulocyte, lower lobe of lung, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, Paneth cell, pharynx, right lung, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, upper lobe of left lung. Use these groups to spot repeated connection types before inspecting the individual relationships.

Interleukin-7 receptor-α

Top relations

Gene ontology · 29
Interleukin-7 receptor-α → antigen binding, B cell proliferation, cell morphogenesis, cell surface receptor signaling pathway, clathrin-coated vesicle membrane, cytokine receptor activity, external side of plasma membrane, extracellular region, homeostasis of number of cells, immune response, immunoglobulin production, integral component of membrane, interleukin-7 receptor activity, interleukin-7-mediated signaling pathway, lymph node development, membrane, membrane organization, negative regulation of T cell apoptotic process, negative regulation of T cell mediated cytotoxicity, plasma membrane
Bgee · 18
Interleukin-7 receptor-α → appendix, blood, bone marrow, epithelium of nasopharynx, gallbladder, granulocyte, lower lobe of lung, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, Paneth cell, pharynx, right lung, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, upper lobe of left lung
RNA expression pattern · 18
Interleukin-7 receptor-α → appendix, blood, bone marrow, epithelium of nasopharynx, gallbladder, granulocyte, lower lobe of lung, lumbar subsegment of spinal cord, lymph node, mesenteric lymph nodes, Paneth cell, pharynx, right lung, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, upper lobe of left lung
Band · 2
Interleukin-7 receptor-α → 15 A1|15 4.16 cM, 5p13.2
Chr. · 2
Interleukin-7 receptor-α → Chromosome 15 (mouse), Chromosome 5 (human)
End · 2
Interleukin-7 receptor-α → 35,879,603 bp, 9,530,262 bp
Aliases · 1
Interleukin-7 receptor-α → IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor
Available structures · 1
Interleukin-7 receptor-α → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP1
BioGPS · 1
Interleukin-7 receptor-α → More reference expression data
Databases · 1
Interleukin-7 receptor-α → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human interleukin-7 receptor bp chr band gene il7r subunit chromosome protein external mouse location pdb uniprot alpha il7r-α available cd127

Interleukin-7 receptor-α relationships Subject–Predicate–Object triples

TTTA extracted 88 structured relationships around Interleukin-7 receptor-α. Examples in this analysis include Interleukin-7 receptor-α → Aliases → IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor and Interleukin-7 receptor-α → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP1. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Interleukin-7 receptor-αAliasesIL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA, Interleukin-7 receptor-α, interleukin 7 receptor1.00infobox
Interleukin-7 receptor-αAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3DI2, 3DI3, 3UP11.00infobox
Interleukin-7 receptor-αBand5p13.21.00infobox
Interleukin-7 receptor-αBand15 A1|15 4.16 cM1.00infobox
Interleukin-7 receptor-αBgeeright lung1.00infobox
Interleukin-7 receptor-αBgeegranulocyte1.00infobox
Interleukin-7 receptor-αBgeelymph node1.00infobox
Interleukin-7 receptor-αBgeelower lobe of lung1.00infobox
Interleukin-7 receptor-αBgeeepithelium of nasopharynx1.00infobox
Interleukin-7 receptor-αBgeeappendix1.00infobox
Interleukin-7 receptor-αBgeeblood1.00infobox
Interleukin-7 receptor-αBgeethymus1.00infobox
Interleukin-7 receptor-αBgeeupper lobe of left lung1.00infobox
Interleukin-7 receptor-αBgeegallbladder1.00infobox
Interleukin-7 receptor-αBgeemesenteric lymph nodes1.00infobox
Interleukin-7 receptor-αBgeespleen1.00infobox
Interleukin-7 receptor-αBgeetibiofemoral joint1.00infobox
Interleukin-7 receptor-αBgeesubcutaneous adipose tissue1.00infobox
Interleukin-7 receptor-αBgeebone marrow1.00infobox
Interleukin-7 receptor-αBgeePaneth cell1.00infobox
Interleukin-7 receptor-αBgeepharynx1.00infobox
Interleukin-7 receptor-αBgeelumbar subsegment of spinal cord1.00infobox
Interleukin-7 receptor-αBioGPSMore reference expression data1.00infobox
Interleukin-7 receptor-αChr.Chromosome 5 (human)1.00infobox
Interleukin-7 receptor-αChr.Chromosome 15 (mouse)1.00infobox
Interleukin-7 receptor-αDatabasesNCBI: entry; OMA: entry1.00infobox
Interleukin-7 receptor-αEnd35,879,603 bp1.00infobox
Interleukin-7 receptor-αEnd9,530,262 bp1.00infobox
Interleukin-7 receptor-αEnsemblENSG000001686851.00infobox
Interleukin-7 receptor-αEntrez35751.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Interleukin-7 receptor-α bring nearby vocabulary together. In this analysis, examples include Receptor, Subunit and Alpha. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Interleukin-7 receptor-α
    • Receptor
    • Subunit
    • Alpha
    • Available
    • Il7r
    • Pdb
    • Uniprot
    • Gene
    • Human
    • Cd127
    • Cytokine
    • Differentiation
  • interleukin-7 receptor-α
    • Receptor
    • Subunit
    • Alpha
    • Available
    • Il7r
    • Pdb
    • Uniprot
    • Gene
    • Human
    • Cd127
    • Cytokine
    • Differentiation
  • type i cytokine receptor
    • Subunit
    • Available
    • Pdb
    • Tslp
    • Uniprot
    • Human
    • A1
    • Cytokine
    • Differentiation
    • End
    • External
    • Il7r-α
  • interleukin-7 receptor
    • Receptor
    • Subunit
    • Alpha
    • Available
    • Il7r
    • Pdb
    • Uniprot
    • Gene
    • Human
    • Cd127
    • Cytokine
    • Differentiation
  • gene
    • Il7r
    • Location
    • Chromosome
    • A1
    • Bp
    • Chr
    • End
    • External
    • Human
    • Protein
    • Search
    • Interleukin-7
  • protein
    • A1
    • Cytokine
    • End
    • External
    • P16871
    • P16872
    • Receptor
    • Search
    • Location
    • Mouse
    • Uniprot
    • Band
  • overview
    • Pdbe-kb
    • Pdb
    • Uniprot
    • Subunit
    • P16871
    • P16872
    • Receptor
  • tslp
    • Cytokine
    • Il7r-α
    • Subunit
    • Interleukin-7
    • Receptor

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the Interleukin-7 receptor-α map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

Interleukin-7 receptor-α

Nodes8
Edges7
Triples88
Avg. degree1.75
Density0.25
Components1

Source & methodology

TTTA analyzes the structure around Interleukin-7 receptor-α to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Interleukin-7 receptor-α · EN edition · Analysis: TopicsToTalkAbout

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