CASK

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Explore the main themes, entities and connections around CASK. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Interactions

Interact KCNJ4 APBA1 ATP2B4 CINAP

15 related topics

Function

Synaptic TBR1 Neurexins Syndecans

4 related topics

Clinical importance

X-linked intellectual disability Intellectual developmental disorder and microcephaly with pontine and cerebellar hypoplasia Glutamate GABA

4 related topics

Gene

X chromosome

1 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1: ↗
Aliases: CASK, CAGH39, CAMGUK, CMG, FGS4, LIN2, MICPCH, MRXSNA, TNRC8, calcium/calmodulin-dependent serine protein kinase (MAGUK family), calcium/calmodulin dependent serine protein kina…
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KGD, 1KWA, 1ZL8, 3C0G, 3C0H, 3C0I, 3MFR, 3MFS, 3MFT, 3MFU, 3TAC
Band: Xp11.4 · X A1.1|X 8.43 cM
Bgee: buccal mucosa cell · hair follicle · duodenum · jejunal mucosa · pancreatic ductal cell
BioGPS: More reference expression data

Topics to explore

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Overview

Protein
Gene
MICPCH Mental retardation and microcephaly with pontine and cerebellar hypoplasia

Gene

X chromosome

Function

Synaptic Synapse
TBR1
Neurexins Neurexin
Syndecans Syndecan

Clinical importance

Interactions

Interact Protein-protein interaction
KCNJ4
APBA1
ATP2B4
CINAP CINAP?action=edit&redlink=1
DLG1
DLG4
F11 receptor
ID1
KCNJ12
LIN7A
Nephrin
Parkin (ligase)
RPH3A
SDC2

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes33

Edges32

Triples133

Avg. degree1.94

Density0.060606

Components1

How this topic connects Entity context

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CASK

Top relations

Gene ontology · 42

CASK → actin cytoskeleton, ATP binding, basement membrane, basolateral plasma membrane, calcium ion import, calmodulin binding, cell adhesion, cell-cell junction, ciliary membrane, cytoplasm, cytosol, focal adhesion, GDP metabolic process, GMP metabolic process, guanylate kinase activity, kinase activity, membrane, negative regulation of cell-matrix adhesion, negative regulation of cellular response to growth factor stimulus, negative regulation of keratinocyte proliferation

Bgee · 19

CASK → Achilles tendon, buccal mucosa cell, condyle, conjunctival fornix, duodenum, fossa, ganglionic eminence, genital tubercle, hair follicle, Ileal epithelium, jejunal mucosa, optic nerve, pancreatic ductal cell, Paneth cell, Rostral migratory stream, superior vestibular nucleus, tail of embryo, trigeminal ganglion, ventricular zone

RNA expression pattern · 19

related to External links · 11

CASK → Australia, CASK Research Foundation, CASK-related, Foundation, Human CASK, MICPCH, MICPCHAngelina CASK Neurological Research, Project CASK, UCSC Genome Browser, UK, United States

related to Clinical importance · 9

CASK → As, Females, It, Males, Research, The, These, This, X-linked

related to Interactions · 3

CASK → KCNJ4APBA1ATP2B4CINAP, RPH3ASDC2, TBR1DLG1DLG4F11

Band · 2

CASK → X A1.1|X 8.43 cM, Xp11.4

Chr. · 2

CASK → X chromosome (human), X chromosome (mouse)

End · 2

CASK → 13,717,606 bp, 41,923,554 bp

2.7.11.1 · 1

CASK → ↗

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene protein bp human chr band chromosome micpch location mutations calcium serine kinase function synaptic including disorders x-linked membrane mouse

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
CASK	2.7.11.1	↗	1.00	infobox
CASK	Aliases	CASK, CAGH39, CAMGUK, CMG, FGS4, LIN2, MICPCH, MRXSNA, TNRC8, calcium/calmodulin-dependent serine protein kinase (MAGUK family), calcium/calmodulin dependent serine protein kina…	1.00	infobox
CASK	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1KGD, 1KWA, 1ZL8, 3C0G, 3C0H, 3C0I, 3MFR, 3MFS, 3MFT, 3MFU, 3TAC	1.00	infobox
CASK	Band	Xp11.4	1.00	infobox
CASK	Band	X A1.1\|X 8.43 cM	1.00	infobox
CASK	Bgee	buccal mucosa cell	1.00	infobox
CASK	Bgee	hair follicle	1.00	infobox
CASK	Bgee	duodenum	1.00	infobox
CASK	Bgee	jejunal mucosa	1.00	infobox
CASK	Bgee	pancreatic ductal cell	1.00	infobox
CASK	Bgee	optic nerve	1.00	infobox
CASK	Bgee	Achilles tendon	1.00	infobox
CASK	Bgee	ganglionic eminence	1.00	infobox
CASK	Bgee	ventricular zone	1.00	infobox
CASK	Bgee	superior vestibular nucleus	1.00	infobox
CASK	Bgee	genital tubercle	1.00	infobox
CASK	Bgee	Ileal epithelium	1.00	infobox
CASK	Bgee	tail of embryo	1.00	infobox
CASK	Bgee	Rostral migratory stream	1.00	infobox
CASK	Bgee	condyle	1.00	infobox
CASK	Bgee	conjunctival fornix	1.00	infobox
CASK	Bgee	fossa	1.00	infobox
CASK	Bgee	trigeminal ganglion	1.00	infobox
CASK	Bgee	Paneth cell	1.00	infobox
CASK	BioGPS	More reference expression data	1.00	infobox
CASK	Chr.	X chromosome (human)	1.00	infobox
CASK	Chr.	X chromosome (mouse)	1.00	infobox
CASK	Databases	NCBI: entry; OMA: entry	1.00	infobox
CASK	End	41,923,554 bp	1.00	infobox
CASK	End	13,717,606 bp	1.00	infobox

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