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Restriction enzyme

A restriction enzyme, restriction endonuclease, REase, ENase or restrictase is an enzyme that cleaves DNA into fragments at or near specific recognition sites within molecules known as restriction sites. Restriction enzymes are one class of the broader endonuclease group of enzymes. Restriction enzymes are commonly classified into five types, which…

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Key facts & relationships

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AlphaFold
IPR011335
Available protein structures:
IPR011335
InterPro
IPR011335
PDB
IPR011335
Pfam clan
CL0236
SCOP2
1wte / SCOPe / SUPFAM

Topics to explore

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Overview

History

Origins

Recognition site

Types

Nomenclature

Applications

Advanced semantic analysis

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Map overview Semantic statistics

Restriction enzyme

Nodes139
Edges138
Triples201
Avg. degree1.99
Density0.014388
Components1

How this topic connects Entity context

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Restriction enzyme

Top relations

related to Type II · 34
Restriction enzyme → AdoMet, ATP, BcgI, BplI, Bpu10I, BslI, DNA, DpnI, Eco57I, FokI, Golden Gate, II, IIE, IIF, In, It, Mg2, NaeI, NgoMIV, One
related to history · 29
Restriction enzyme → Arber, Daniel Nathans, DNA, Escherichia, For, Giuseppe Bertani, Haemophilus, Hamilton, HindII, If, II, In, It, Jean Weigle, Kathleen Danna, Kent Wilcox, Later, Matthew Meselson, Medicine, Meselson
related to External links · 28
Restriction enzyme → Archived, DNA Restriction Enzymes, Firman, Goodsell DS, Macelis, Medicine Medical Subject Headings, MeSH, Molecular Scissors, Molecule, Month, National Library, Portsmouth, Posfai, RCSB Protein Data Bank, REBASE, Restriction Endonucleases, Restriction Enzyme Database, Restriction Enzymes, Restriction-Modification, Retrieved
related to Type III · 19
Restriction enzyme → AdoMet, ATP, DNA, EcoP15, FXGXG, IV, Mod, N-6, N6, P08763, P08764, PP, Res, S/D/N, The Mod, These, They, Type III, Y/F
related to Types · 18
Restriction enzyme → All, ATP, DNA, DNAType, EC2, EC3, II, III, IV, Naturally, RNAs, S-adenosyl-L-methionine, They, Type, Type II, Type III, Type IV, Types
related to Artificial restriction enzymes · 14
Restriction enzyme → Artificial, Clustered, CRISPR, CRISPR-Cas9, DNA, DNA-binding, FokI, For, IIS, In, Other, Such, TAL, Zinc
related to Type l · 14
Restriction enzyme → AdoMet, ATP, Cleavage, DNA, DNA-binding, HsdM, HsdR, HsdS, K-12, Mg2, S-Adenosyl, The, These, Type
related to Recognition site · 10
Restriction enzyme → CATATG, DNA, EcoRI, GTAATG, GTATAC, In, Inverted, Many, Restriction, The
has application · 7
Restriction enzyme → DNA, For, Isolated, MCS, They, This, To
related to Type V · 7
Restriction enzyme → CRISPRs, DNA, RNA, RNAs, The, They, Type

Important terminology Word statistics

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Important terminology

dna restriction enzymes type recognition enzyme site sites sequence cleavage two used cut one cleave endonucleases sequences also gene specific

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Restriction enzymeAlphaFoldIPR0113351.00infobox
Restriction enzymeAvailable protein structures:IPR0113351.00infobox
Restriction enzymeInterProIPR0113351.00infobox
Restriction enzymePDBIPR0113351.00infobox
Restriction enzymePfam clanCL02361.00infobox
Restriction enzymeSCOP21wte / SCOPe / SUPFAM1.00infobox
Restriction enzymeSymbolRestrct_endonuc-II-like1.00infobox
human insulin used by diabetic patientsinstance ofallowing the large scale production of proteins0.80text
Golden Gate cloninginstance ofthis characteristic is widely used to perform in-vitro cloning techniques0.80text
Restriction enzymehas applicationIsolated0.60section
Restriction enzymehas applicationDNA0.60section
Restriction enzymehas applicationThey0.60section

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