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Sequence motif

In biology, a sequence motif is a nucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function of the macromolecule. For example, an N-glycosylation site motif can be defined as Asn, followed by anything but Pro, followed by either Ser or Thr, followed by anything but Pro residue.

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Motif Representation

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Sequence motif

Nodes63
Edges62
Triples21
Avg. degree1.97
Density0.031746
Components1

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Sequence motif

Top relations

related to overview · 14
Sequence motif → B-form, DNA, For, In, Nevertheless, Noncoding, Outside, Process, RNA, Some, The, They, When, With
is a · 1
Sequence motif → nucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function of the macromolecule

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Important terminology

motif sequence pattern motifs sequences discovery acid amino example dna algorithms notation protein approach also proteins search position consensus notations

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Sequence motifis anucleotide or amino-acid sequence pattern that is widespread and usually assumed to be related to biological function of the macromolecule0.90text
a hidden Markov model.Motifsinstance ofSometimes patterns are defined in terms of a probabilistic model0.80text
consensus sequencesThe notationinstance ofSometimes patterns are defined in terms of a probabilistic model0.80text
MEME using hidden Markov models.A position weight matrixinstance ofPFMs can be experimentally determined from SELEX experiments or computationally discovered by tools0.80text
Pfaminstance ofThe authors were able to show that the motif has DNA binding activity.A similar approach is commonly used by modern protein domain databases0.80text
CisFinder employ nucleotide substitution matrices for motif clusteringinstance ofClustering-Based Methods0.80text
effectively mitigating redundancyinstance ofClustering-Based Methods0.80text
Sequence motifrelated to overviewWhen0.60section
Sequence motifrelated to overviewNevertheless0.60section
Sequence motifrelated to overviewNoncoding0.60section
Sequence motifrelated to overviewB-form0.60section
Sequence motifrelated to overviewDNA0.60section

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