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EcoRI: History, Applications, Art & Standards

EcoRI (pronounced "eco R one") is a type II restriction enzyme isolated from Escherichia coli. It cleaves DNA double helices into fragments at specific sites, and is also a part of the restriction modification system. The enzyme's name originates from the species from which it was isolated: "E" denotes generic name (Escherichia), "co" denotes species…

Language: English [EN]
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EcoRI topic overview

The analysis highlights History, Applications, Art and Standards as prominent areas in the source structure around EcoRI.

Related topics
19
Source areas
4
Connected nodes
23
Extracted relationships
43
Concept neighborhoods
14
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 8 topics
Uses · 5 topics
History · 3 topics
Structure · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR004221 · PF02963
Available protein structures:
IPR004221 · PF02963
CDD
79lll
InterPro
IPR004221
PDB
IPR004221 PF02963 (ECOD; PDBsum)
Pfam
PF02963

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Structure

Uses

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How EcoRI connects Entity context

The extracted context around EcoRI shows recurring relationship patterns in the source. For example, EcoRI → Eco-RI, Medicine Medical Subject Headings, MeSH, National Library, Overview, P00642, PDB, PDBe-KB, Type-2, UniProt Another extracted example is EcoRI → Arg145, DNA, Each, Glu144, In, On, The, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

EcoRI

Top relations

related to External links · 10
EcoRI → Eco-RI, Medicine Medical Subject Headings, MeSH, National Library, Overview, P00642, PDB, PDBe-KB, Type-2, UniProt
related to Tertiary and quaternary structure · 8
EcoRI → Arg145, DNA, Each, Glu144, In, On, The, This
related to history · 7
EcoRI → Daisy Roulland-Dussoix, Herb Boyer, II, It, PhD, Robert Yoshimori, Yoshimori
related to Uses · 4
EcoRI → Conditions, DNA, One, Restriction
AlphaFold · 2
EcoRI → IPR004221, PF02963
Available protein structures: · 2
EcoRI → IPR004221, PF02963
related to Primary structure · 2
EcoRI → D/EXK, PD
see also · 2
EcoRI → EcoRII, EcoRV
CDD · 1
EcoRI → 79lll
InterPro · 1
EcoRI → IPR004221

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

enzyme restriction dna coli structure one used isolated first escherichia also crystal pdb enzymes subunit reaction type ii helices sites

EcoRI relationships Subject–Predicate–Object triples

TTTA extracted 43 structured relationships around EcoRI. Examples in this analysis include EcoRI → AlphaFold → IPR004221 and EcoRI → AlphaFold → PF02963. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
EcoRIAlphaFoldIPR0042211.00infobox
EcoRIAlphaFoldPF029631.00infobox
EcoRIAvailable protein structures:IPR0042211.00infobox
EcoRIAvailable protein structures:PF029631.00infobox
EcoRICDD79lll1.00infobox
EcoRIInterProIPR0042211.00infobox
EcoRIPDBIPR004221 PF02963 (ECOD; PDBsum)1.00infobox
EcoRIPfamPF029631.00infobox
EcoRISCOP21na6 / SCOPe / SUPFAM1.00infobox
EcoRISymbolEcoRI1.00infobox
EcoRIrelated to External linksEco-RI0.60section
EcoRIrelated to External linksNational Library0.60section

Related concept clusters Concept neighborhoods

The concept neighborhoods around EcoRI bring nearby vocabulary together. In this analysis, examples include Restriction, Reaction and Available. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • EcoRI
    • Restriction
    • Reaction
    • Available
    • Ends
    • Ii
    • Like
    • Pdb
    • Sticky
    • Type
    • Enzymes
    • Enzyme
    • One
  • ecori
    • Restriction
    • Reaction
    • Available
    • Ends
    • Ii
    • Like
    • Pdb
    • Sticky
    • Type
    • Enzymes
    • Enzyme
    • One
  • type ii restriction enzyme
    • Ii
    • Type
    • One
    • Available
    • Bound
    • Dna
    • Enzymes
    • Escherichia
    • Pdb
    • Used
    • First
    • Isolated
  • recombinant dna
    • Enzymes
    • Restriction
    • Bound
    • One
    • Used
    • Ecori
    • Also
    • Available
    • Contains
    • Domain
    • Ends
    • Globular
  • restriction modification system
    • Dna
    • Enzymes
    • Used
    • Available
    • Like
    • Molecular
    • Pdb
    • Type
    • Active
    • Also
    • Bound
    • Contains
  • restriction digests
    • Dna
    • Enzymes
    • Used
    • Available
    • Like
    • Molecular
    • Pdb
    • Type
    • Active
    • Also
    • Bound
    • Contains
  • restriction endonucleases
    • Dna
    • Enzymes
    • Used
    • Available
    • Like
    • Molecular
    • Pdb
    • Type
    • Active
    • Also
    • Bound
    • Contains
  • escherichia coli
    • Isolated
    • Enzyme
    • Escherichia
    • Enzyme's
    • Ii
    • Type
    • First
    • One
    • Restriction
    • Yoshimori
    • Ecori

Connections between topic areas Semantic bridges

For EcoRI, one of the stronger structural bridges in this analysis connects EcoRI with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
EcoRI — Overview · splits 15 ⟂ 9
EcoRI — Uses · splits 18 ⟂ 6
EcoRI — History · splits 20 ⟂ 4
EcoRI — Structure · splits 20 ⟂ 4

Map overview Semantic statistics

EcoRI

Nodes24
Edges23
Triples43
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around EcoRI to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications, Art & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — EcoRI · EN edition · Analysis: TopicsToTalkAbout

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