CRISPR

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Map view:

Zoom: 100%

More settings

Connection length 100% Label size 100% Node size 100% Line width 100% Label width 100%

Export map as:

CRISPR topic overview

The analysis highlights History and Applications as prominent areas in the source structure around CRISPR.

Related topics: 117
Source areas: 10
Connected nodes: 127
Extracted relationships: 199
Related term clusters: 30
Bridge connections: 127

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

CRISPR-associated systems · 42 topics

Overview · 20 topics

Evolution · 13 topics

History · 13 topics

Mechanism · 11 topics

Locus structure · 7 topics

Use by phages · 5 topics

Protein Data Bank · 3 topics

Applications · 2 topics

Identification · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains: InterPro
Entrez: 947229
Organism: Escherichia coli
Orthologs: NCBI: entry; OMA: entry
PDB: 4QYZ
RefSeq (Prot): NP_417241.1

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

CRISPR

8DNA · Genome · Prokaryotic

3Yoshizumi Ishino · Alkaline phosphatase · Escherichia coli

24Cas9 · Enzyme · CRISPR gene editing

7S. thermophilus · RNA · CrRNA

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

History

Locus structure

Mechanism

Evolution

Identification

Contig

Use by phages

Applications

Protein Data Bank

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How CRISPR connects Entity context

The extracted context around CRISPR shows recurring relationship patterns in the source. For example, CRISPR → Another, Cas, CRISPR-Cas, DNA, I-F, ICP1, ICP1 CRISPR-Cas, LtrC, Moreover, O1, One, PICI, PICI CpmAB, PICI-encoded Ppi, PICI-like, PICIs, PtiA, PtiB, PtiM, SaPI-sized Another extracted example is CRISPR → CRISPR-DR19, CRISPR-DR2, CRISPR-DR41, CRISPR-DR5, CRISPR-DR52, CRISPR-DR57, CRISPR-DR6, CRISPR-DR65, CRISPR-DR8, CRISPR-DR9, Family RF01315, Family RF01318, Family RF01319, Family RF01321, Family RF01322, Family RF01332, Family RF01350, Family RF01365, Family RF01370, Family RF01378. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Use by phages · 24

CRISPR → Another, Cas, CRISPR-Cas, DNA, I-F, ICP1, ICP1 CRISPR-Cas, LtrC, Moreover, O1, One, PICI, PICI CpmAB, PICI-encoded Ppi, PICI-like, PICIs, PtiA, PtiB, PtiM, SaPI-sized

related to CRISPR RNA structures · 22

CRISPR → CRISPR-DR19, CRISPR-DR2, CRISPR-DR41, CRISPR-DR5, CRISPR-DR52, CRISPR-DR57, CRISPR-DR6, CRISPR-DR65, CRISPR-DR8, CRISPR-DR9, Family RF01315, Family RF01318, Family RF01319, Family RF01321, Family RF01322, Family RF01332, Family RF01350, Family RF01365, Family RF01370, Family RF01378

related to Protein Data Bank · 15

CRISPR → CasA, CasB, CasC, Cascade, CasD, CasE, Overview, P76632, PDB, PDBe-KB, Q46897, Q46898, Q46899, Q46901, UniProt

related to Cas genes and CRISPR subtypes · 14

CRISPR → Cas, Cas1, Cas9, Class, Classification, Collectively, CRISPR-Cas, II, III, IV, Many, Most CRISPR-Cas, Small, VI

related to Cas12a · 12

CRISPR → Cas12a, Cas9, Class II Type, Cpf1, CRISPR RNA, CRISPR-associated, DNA, G-rich' PAMs, NGG-3, PAM, T-rich, TTTV-3

related to Cas13 · 12

CRISPR → Cas12, Cas13, Cas9, CRISPR RNA, CRISPR-associated, DNA, Its PAM-independent, KRAS-G12D, REPAIR, RNA, SHERLOCK, Usher

related to Biogenesis · 11

CRISPR → Cas, Cas6, Cas6e, Cas6f, Cleavage, CRISPR-Cas, CRISPR-RNA, I-E, I-F, These Cas, Type III

related to Evolution · 8

CRISPR → Cas, Cas1-like, CRISPR-Cas, Darwinian, Indeed, Koonin, Lamarck, Lamarckian

related to CRISPR-associated systems · 7

CRISPR → Cas, CRISPR's, CRISPR-associated, CRISPR-cas, DNA, Jansen's, The Cas

related to Spacer acquisition · 7

CRISPR → Cas1, Cas2, CRISPR-Cas, DNA, Multiple Cas1, Mutation, Representative Cas2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

dna systems phage system rna sequence spacer spacers cas crispr-cas crrna type repeats sequences cas9 proteins mechanism evolution cas1 protein

CRISPR relationships Subject–Predicate–Object triples

TTTA extracted 199 structured relationships around CRISPR. Examples in this analysis include CRISPR → Domains → InterPro and CRISPR → Entrez → 947229. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
CRISPR	Domains	InterPro	1.00	infobox
CRISPR	Entrez	947229	1.00	infobox
CRISPR	Organism	Escherichia coli	1.00	infobox
CRISPR	Orthologs	NCBI: entry; OMA: entry	1.00	infobox
CRISPR	PDB	4QYZ	1.00	infobox
CRISPR	RefSeq (Prot)	NP_417241.1	1.00	infobox
CRISPR	Search for	Search forStructuresSwiss-modelDomainsInterPro	1.00	infobox
CRISPR	Structures	Swiss-model	1.00	infobox
CRISPR	Symbol	CRISPR	1.00	infobox
CRISPR	UniProt	P38036	1.00	infobox
bacteria	instance of	is a family of DNA sequences found in the genomes of prokaryotic organisms	0.80	text
archaea	instance of	is a family of DNA sequences found in the genomes of prokaryotic organisms	0.80	text

Related concept clusters Related term clusters

The concept neighborhoods around CRISPR bring nearby vocabulary together. In this analysis, examples include Sequence, Spacers and Dna. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

CRISPR
- Sequence
- Spacers
- Dna
- Spacer
- System
- Sequences
- Genomes
- Repeats
- Cas
- Phage
- Crrna
- Rna
crispr
- Sequence
- Spacers
- Dna
- Spacer
- System
- Sequences
- Genomes
- Repeats
- Cas
- Phage
- Crrna
- Rna
dna
- Cas9
- Rna
- Sequences
- Phage
- Systems
- Repeats
- Crrna
- Genomes
- Protein
- Target
- Spacers
- Mechanism
bacteria
- Found
- Crispr-cas
- Mechanism
- Sequences
- System
- Repeats
- Genomes
- Phage
- Spacers
- Genes
- Acquisition
- Pam
cas9
- Rna
- Dna
- Protein
- Sequences
- Crrna
- Genes
- Pam
- Thermophilus
- Target
- Gene
- Crispr
- Cas
direct repeats
- Sequences
- Genomes
- Repeat
- Type
- Spacers
- Protein
- Systems
- Crrna
- Proteins
- Rna
- Cas
- Sequence
extrachromosomal dna
- Cas9
- Rna
- Sequences
- Phage
- Systems
- Repeats
- Crrna
- Genomes
- Protein
- Target
- Spacers
- Mechanism
rna interference
- Crrna
- Target
- Mechanism
- Systems
- Cas
- Crispr-cas
- Pam
- Sequence
- Structure
- System
- Gene
- Repeat

Connections between topic areas Semantic bridges

For CRISPR, one of the stronger structural bridges in this analysis connects CRISPR with CRISPR-associated systems. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

CRISPR — CRISPR-associated systems · splits 85 ⟂ 43

CRISPR — Overview · splits 107 ⟂ 21

CRISPR — History · splits 114 ⟂ 14

CRISPR — Evolution · splits 114 ⟂ 14

CRISPR — Mechanism · splits 116 ⟂ 12

CRISPR — Locus structure · splits 120 ⟂ 8

CRISPR — Use by phages · splits 122 ⟂ 6

CRISPR — Protein Data Bank · splits 124 ⟂ 4

CRISPR — Applications · splits 125 ⟂ 3

Map overview Semantic statistics

CRISPR

Nodes128

Edges127

Triples199

Avg. degree1.98

Density0.015625

Components1

Source & methodology

TTTA analyzes the structure around CRISPR to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CRISPR · EN edition · Analysis: TopicsToTalkAbout

CRISPR: History & Applications

CRISPR topic overview

What this topic covers Research coverage

Key facts & relationships

Start with your topic. Discover where to go next.

Questions to explore

Explore all related topics Closing gaps

Overview

History

CRISPR-associated systems

Locus structure

Mechanism

Evolution

Identification

Use by phages

Applications

Protein Data Bank

For the semantics nerds

Advanced semantic analysis

How CRISPR connects Entity context

CRISPR

Top relations

Important terminology

Important terminology

CRISPR relationships Subject–Predicate–Object triples

Related concept clusters Related term clusters

Connections between topic areas Semantic bridges

Map overview Semantic statistics

CRISPR

Source & methodology