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CRISPR

CRISPR (/ˈkrɪspər/; acronym for clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. Each sequence within an individual prokaryotic CRISPR is derived from a DNA fragment of a bacteriophage that had previously infected the prokaryote or one of…

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Domains
InterPro
Entrez
947229
Organism
Escherichia coli
Orthologs
NCBI: entry; OMA: entry
PDB
4QYZ
RefSeq (Prot)
NP_417241.1

Topics to explore

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Overview

History

CRISPR-associated systems

Locus structure

Mechanism

Evolution

Identification

Use by phages

Applications

Protein Data Bank

Advanced semantic analysis

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Map overview Semantic statistics

CRISPR

Nodes129
Edges128
Triples273
Avg. degree1.98
Density0.015504
Components1

How this topic connects Entity context

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CRISPR

Top relations

related to Use by phages · 28
CRISPR → Another, Cas, CRISPR-Cas, DNA, I-F, ICP1, ICP1 CRISPR-Cas, In, It, LtrC, Moreover, O1, One, PICI, PICI CpmAB, PICI-encoded Ppi, PICI-like, PICIs, PtiA, PtiB
related to CRISPR RNA structures · 22
CRISPR → CRISPR-DR19, CRISPR-DR2, CRISPR-DR41, CRISPR-DR5, CRISPR-DR52, CRISPR-DR57, CRISPR-DR6, CRISPR-DR65, CRISPR-DR8, CRISPR-DR9, Family RF01315, Family RF01318, Family RF01319, Family RF01321, Family RF01322, Family RF01332, Family RF01350, Family RF01365, Family RF01370, Family RF01378
related to External links · 21
CRISPR → Advanced Gene Editing, April, Archived, Birth, Breakthrough Technology, Congressional Research Service, CRISPR-Cas9, December, Episode, Genome Engineering, Human Nature, Jennifer Doudna, NOVA, November, October, PBS, PDF, Retrieved, Season, September
related to Cas genes and CRISPR subtypes · 16
CRISPR → Cas, Cas1, Cas9, Class, Classification, Collectively, CRISPR-Cas, Each, II, III, IV, Many, Most CRISPR-Cas, Small, The, VI
related to Cas13 · 15
CRISPR → Cas12, Cas13, Cas9, CRISPR RNA, CRISPR-associated, DNA, It, Its PAM-independent, KRAS-G12D, REPAIR, RNA, SHERLOCK, The, This, Usher
related to Evolution · 15
CRISPR → But, Cas, Cas1-like, CRISPR-Cas, Darwinian, For, However, Indeed, Koonin, Lamarck, Lamarckian, On, The, These, We
related to Protein Data Bank · 15
CRISPR → CasA, CasB, CasC, Cascade, CasD, CasE, Overview, P76632, PDB, PDBe-KB, Q46897, Q46898, Q46899, Q46901, UniProt
related to Biogenesis · 14
CRISPR → Cas, Cas6, Cas6e, Cas6f, Cleavage, CRISPR-Cas, CRISPR-RNA, I-E, I-F, In, The, These Cas, This, Type III
related to Cas12a · 13
CRISPR → Cas12a, Cas9, Class II Type, Cpf1, CRISPR RNA, CRISPR-associated, DNA, G-rich' PAMs, In, NGG-3, PAM, T-rich, TTTV-3
related to CRISPR-associated systems · 11
CRISPR → All, Cas, CRISPR's, CRISPR-associated, CRISPR-cas, DNA, However, In, Jansen's, The, The Cas

Important terminology Word statistics

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Important terminology

dna systems phage system rna sequence spacer spacers cas crispr-cas crrna type repeats sequences cas9 proteins mechanism evolution cas1 protein

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CRISPRDomainsInterPro1.00infobox
CRISPREntrez9472291.00infobox
CRISPROrganismEscherichia coli1.00infobox
CRISPROrthologsNCBI: entry; OMA: entry1.00infobox
CRISPRPDB4QYZ1.00infobox
CRISPRRefSeq (Prot)NP_417241.11.00infobox
CRISPRSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CRISPRStructuresSwiss-model1.00infobox
CRISPRSymbolCRISPR1.00infobox
CRISPRUniProtP380361.00infobox
bacteriainstance ofis a family of DNA sequences found in the genomes of prokaryotic organisms0.80text
archaeainstance ofis a family of DNA sequences found in the genomes of prokaryotic organisms0.80text

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