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Cas9 (CRISPR-associated protein 9) is a DNA cutting endonuclease that is part of the CRISPR immune system in bacteria and archaea. It has been adapted for use as a CRISPR genome editing tool. The CRISPR-Cas9 system is widely used in genetic engineering, medicine, agriculture, and biotechnology.
History, Applications, Research & Technology
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dna dcas9 crispr rna genome transcription gene pam system cleavage target editing sequence complex genes endonuclease guide spacer used foreign
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Cas9 | Alt. symbols | SpCas9 | 1.00 | infobox |
| Cas9 | Chromosome | Genomic: 0.85 - 0.86 Mb | 1.00 | infobox |
| Cas9 | Domains | InterPro | 1.00 | infobox |
| Cas9 | EC number | 3.1.-.- | 1.00 | infobox |
| Cas9 | Entrez | 901176 | 1.00 | infobox |
| Cas9 | Organism | Streptococcus pyogenes M1 | 1.00 | infobox |
| Cas9 | Orthologs | NCBI: entry; OMA: entry | 1.00 | infobox |
| Cas9 | PDB | 4OO8 | 1.00 | infobox |
| Cas9 | RefSeq (mRNA) | NC_002737.2 | 1.00 | infobox |
| Cas9 | RefSeq (Prot) | NP_269215.1 | 1.00 | infobox |
| Cas9 | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| Cas9 | Structures | Swiss-model | 1.00 | infobox |
| Cas9 | Symbol | cas9 | 1.00 | infobox |
| Cas9 | UniProt | Q99ZW2 | 1.00 | infobox |
| Cas9 | is a | 160-kilodalton endonuclease that requires a guide RNA composed of two distinct RNA molecules | 0.90 | text |
| Cas9 | is a | RNA-guided DNA endonuclease enzyme associated with the Clustered Regularly Interspaced Short Palindromic Repeats | 0.90 | text |
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