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PSMA7

Proteasome subunit alpha type-7 also known as 20S proteasome subunit alpha-4 is a protein that in humans is encoded by the PSMA7 gene. This protein is one of the 17 essential subunits (alpha subunits 1–7, constitutive beta subunits 1–7, and inducible subunits including beta1i, beta2i, beta5i) that contributes to the complete assembly of 20S proteasome…

Measurement, Clinical significance & Interactions

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Clinical significance

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Interactions

3 related topics

Function

2 related topics

Structure

2 related topics

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Aliases
PSMA7, C6, HSPC, RC6-1, XAPC7, HEL-S-276, proteasome subunit alpha 7, proteasome 20S subunit alpha 7
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4R3O, 4R67, 1IRU, 5A0Q
Band
20q13.33 · 2|2 H4
Bgee
gastrocnemius muscle · oocyte · right adrenal gland · left adrenal gland · left coronary artery
BioGPS
More reference expression data
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

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Function

Structure

Clinical significance

Interactions

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Map overview Semantic statistics

PSMA7

Nodes68
Edges67
Triples119
Avg. degree1.97
Density0.029412
Components1

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PSMA7

Top relations

Gene ontology · 45
PSMA7 → anaphase-promoting complex-dependent catabolic process, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, cytoplasm, cytosol, endopeptidase activity, extracellular exosome, Fc-epsilon receptor signaling pathway, hydrolase activity, identical protein binding, interleukin-1-mediated signaling pathway, MAPK cascade, negative regulation of canonical Wnt signaling pathway, negative regulation of G2/M transition of mitotic cell cycle, NIK/NF-kappaB signaling, nucleoplasm, nucleus, peptidase activity, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, postsynapse
Bgee · 19
PSMA7 → abdominal wall, apex of heart, blastocyst, embryo, endocardial cushion, epiblast, gastrocnemius muscle, left adrenal cortex, left adrenal gland, left coronary artery, mandibular prominence, maxillary prominence, morula, muscle of thigh, oocyte, right adrenal cortex, right adrenal gland, right lung, ventricular zone
RNA expression pattern · 19
PSMA7 → abdominal wall, apex of heart, blastocyst, embryo, endocardial cushion, epiblast, gastrocnemius muscle, left adrenal cortex, left adrenal gland, left coronary artery, mandibular prominence, maxillary prominence, morula, muscle of thigh, oocyte, right adrenal cortex, right adrenal gland, right lung, ventricular zone
related to Expression · 6
PSMA7 → Isoelectric, Multiple, Proteasome, T1A, The, This
Band · 2
PSMA7 → 20q13.33, 2|2 H4
Chr. · 2
PSMA7 → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
PSMA7 → 179,684,226 bp, 62,143,440 bp
related to Interactions · 2
PSMA7 → HIF1A, PLK1
Aliases · 1
PSMA7 → PSMA7, C6, HSPC, RC6-1, XAPC7, HEL-S-276, proteasome subunit alpha 7, proteasome 20S subunit alpha 7
Available structures · 1
PSMA7 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4R3O, 4R67, 1IRU, 5A0Q

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Important terminology

proteasome protein subunit alpha 20s gene complex ups bp human band subunits chromosome chr role proteolysis assembly core proteolytic also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
PSMA7AliasesPSMA7, C6, HSPC, RC6-1, XAPC7, HEL-S-276, proteasome subunit alpha 7, proteasome 20S subunit alpha 71.00infobox
PSMA7Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4R3O, 4R67, 1IRU, 5A0Q1.00infobox
PSMA7Band20q13.331.00infobox
PSMA7Band2|2 H41.00infobox
PSMA7Bgeegastrocnemius muscle1.00infobox
PSMA7Bgeeoocyte1.00infobox
PSMA7Bgeeright adrenal gland1.00infobox
PSMA7Bgeeleft adrenal gland1.00infobox
PSMA7Bgeeleft coronary artery1.00infobox
PSMA7Bgeeapex of heart1.00infobox
PSMA7Bgeeright adrenal cortex1.00infobox
PSMA7Bgeeright lung1.00infobox
PSMA7Bgeeleft adrenal cortex1.00infobox
PSMA7Bgeemuscle of thigh1.00infobox
PSMA7Bgeeblastocyst1.00infobox
PSMA7Bgeeembryo1.00infobox
PSMA7Bgeeendocardial cushion1.00infobox
PSMA7Bgeemorula1.00infobox
PSMA7Bgeeventricular zone1.00infobox
PSMA7Bgeemaxillary prominence1.00infobox
PSMA7Bgeeabdominal wall1.00infobox
PSMA7Bgeemandibular prominence1.00infobox
PSMA7Bgeeepiblast1.00infobox
PSMA7BioGPSMore reference expression data1.00infobox
PSMA7Chr.Chromosome 20 (human)1.00infobox
PSMA7Chr.Chromosome 2 (mouse)1.00infobox
PSMA7DatabasesNCBI: entry; OMA: entry1.00infobox
PSMA7End62,143,440 bp1.00infobox
PSMA7End179,684,226 bp1.00infobox
PSMA7EnsemblENSG000001011821.00infobox

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