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P2RX7

P2X purinoceptor 7 is a protein that in humans is encoded by the P2RX7 gene.

Pharmacology, Clinical significance & Structure and kinetics

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Pharmacology

15 related topics

Clinical significance

12 related topics

Structure and kinetics

8 related topics

Overview

16 related topics

Key facts & relationships

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Aliases
P2RX7, P2X7, purinergic receptor P2X 7
Band
12q24.31 · 5|5 F
Bgee
inferior ganglion of vagus nerve · endothelial cell · corpus callosum · monocyte · subthalamic nucleus
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 5 (mouse)
Databases
NCBI: entry; OMA: entry

Topics to explore

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Overview

Structure and kinetics

Pharmacology

Receptor trafficking

Recruitment of pannexin

Clinical significance

Advanced semantic analysis

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Map overview Semantic statistics

P2RX7

Nodes65
Edges64
Triples180
Avg. degree1.97
Density0.030769
Components1

How this topic connects Entity context

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P2RX7

Top relations

Gene ontology · 107
P2RX7 → apoptotic signaling pathway, ATP binding, bleb, bleb assembly, blood coagulation, calcium ion transport, cation transmembrane transport, cation transport, cell morphogenesis, cell surface receptor signaling pathway, cell volume homeostasis, cell-cell junction, cellular response to dsRNA, cellular response to extracellular stimulus, cellular response to organic cyclic compound, ceramide biosynthetic process, channel activity, collagen metabolic process, cytolysis, cytoplasm
Bgee · 20
P2RX7 → choroid plexus of fourth ventricle, corpus callosum, dentate gyrus of hippocampal formation granule cell, embryo, endothelial cell, entorhinal cortex, esophagus, globus pallidus, inferior ganglion of vagus nerve, internal globus pallidus, lip, lumbar subsegment of spinal cord, monocyte, optic nerve, perirhinal cortex, primary visual cortex, right ventricle, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area
RNA expression pattern · 20
P2RX7 → choroid plexus of fourth ventricle, corpus callosum, dentate gyrus of hippocampal formation granule cell, embryo, endothelial cell, entorhinal cortex, esophagus, globus pallidus, inferior ganglion of vagus nerve, internal globus pallidus, lip, lumbar subsegment of spinal cord, monocyte, optic nerve, perirhinal cortex, primary visual cortex, right ventricle, subthalamic nucleus, superior vestibular nucleus, ventral tegmental area
related to External links · 6
P2RX7 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
Band · 2
P2RX7 → 12q24.31, 5|5 F
Chr. · 2
P2RX7 → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
P2RX7 → 121,188,032 bp, 122,829,495 bp
Aliases · 1
P2RX7 → P2RX7, P2X7, purinergic receptor P2X 7
BioGPS · 1
P2RX7 → More reference expression data
Databases · 1
P2RX7 → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

p2x7 receptor atp receptors gene bp cells human cell chr band inflammation calcium p2x leads chromosome 12 also response extracellular

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
P2RX7AliasesP2RX7, P2X7, purinergic receptor P2X 71.00infobox
P2RX7Band12q24.311.00infobox
P2RX7Band5|5 F1.00infobox
P2RX7Bgeeinferior ganglion of vagus nerve1.00infobox
P2RX7Bgeeendothelial cell1.00infobox
P2RX7Bgeecorpus callosum1.00infobox
P2RX7Bgeemonocyte1.00infobox
P2RX7Bgeesubthalamic nucleus1.00infobox
P2RX7Bgeesuperior vestibular nucleus1.00infobox
P2RX7Bgeeventral tegmental area1.00infobox
P2RX7Bgeeglobus pallidus1.00infobox
P2RX7Bgeeinternal globus pallidus1.00infobox
P2RX7Bgeeoptic nerve1.00infobox
P2RX7Bgeeright ventricle1.00infobox
P2RX7Bgeeperirhinal cortex1.00infobox
P2RX7Bgeelip1.00infobox
P2RX7Bgeeesophagus1.00infobox
P2RX7Bgeeentorhinal cortex1.00infobox
P2RX7Bgeechoroid plexus of fourth ventricle1.00infobox
P2RX7Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
P2RX7Bgeelumbar subsegment of spinal cord1.00infobox
P2RX7Bgeeembryo1.00infobox
P2RX7Bgeeprimary visual cortex1.00infobox
P2RX7BioGPSMore reference expression data1.00infobox
P2RX7Chr.Chromosome 12 (human)1.00infobox
P2RX7Chr.Chromosome 5 (mouse)1.00infobox
P2RX7DatabasesNCBI: entry; OMA: entry1.00infobox
P2RX7End121,188,032 bp1.00infobox
P2RX7End122,829,495 bp1.00infobox
P2RX7EnsemblENSG000000890411.00infobox

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