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P2RX4

P2X purinoceptor 4 is a protein that in humans is encoded by the P2RX4 gene. P2X purinoceptor 4 is a member of the P2X receptor family. P2X receptors are trimeric protein complexes that can be homomeric or heteromeric. These receptors are ligand-gated cation channels that open in response to ATP binding. Each receptor subtype, determined by the subunit…

Measurement, Structure & Receptor trafficking

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Aliases
P2RX4, P2X4, P2X4R, purinergic receptor P2X 4
Band
12q24.31 · 5 F|5 62.53 cM
Bgee
mucosa of transverse colon · cerebellar hemisphere · right hemisphere of cerebellum · granulocyte · body of pancreas
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 5 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

Structure

Gating mechanism

Receptor trafficking

Pharmacology

Neuropathic pain

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Map overview Semantic statistics

P2RX4

Nodes75
Edges74
Triples124
Avg. degree1.97
Density0.026667
Components1

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P2RX4

Top relations

Gene ontology · 58
P2RX4 → apoptotic signaling pathway, ATP binding, axon, blood coagulation, cadherin binding, cation transmembrane transport, cell junction, cellular response to ATP, copper ion binding, dendrite, dendritic spine, endothelial cell activation, excitatory postsynaptic potential, extracellular exosome, extracellularly ATP-gated cation channel activity, identical protein binding, integral component of membrane, integral component of nuclear inner membrane, integral component of plasma membrane, ion channel activity
Bgee · 20
P2RX4 → body of pancreas, cerebellar hemisphere, decidua, granulocyte, Ileal epithelium, lacrimal gland, left colon, lesser wing of sphenoid bone, monocyte, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, nasal septum, parotid gland, rectum, right hemisphere of cerebellum, stroma of bone marrow, stromal cell of endometrium, submandibular gland, yolk sac
RNA expression pattern · 20
P2RX4 → body of pancreas, cerebellar hemisphere, decidua, granulocyte, Ileal epithelium, lacrimal gland, left colon, lesser wing of sphenoid bone, monocyte, mucosa of ileum, mucosa of sigmoid colon, mucosa of transverse colon, nasal septum, parotid gland, rectum, right hemisphere of cerebellum, stroma of bone marrow, stromal cell of endometrium, submandibular gland, yolk sac
related to External links · 6
P2RX4 → Medicine, Medicine Medical Subject Headings, MeSH, National Library, This, United States National Library
Band · 2
P2RX4 → 12q24.31, 5 F|5 62.53 cM
Chr. · 2
P2RX4 → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
P2RX4 → 121,234,106 bp, 122,867,801 bp
Aliases · 1
P2RX4 → P2RX4, P2X4, P2X4R, purinergic receptor P2X 4
BioGPS · 1
P2RX4 → More reference expression data
Databases · 1
P2RX4 → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

receptor receptors p2x4 p2x desensitization cell human bp gene atp protein activation chr band tm2 cytoplasmic open response p2x3 cap

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
P2RX4AliasesP2RX4, P2X4, P2X4R, purinergic receptor P2X 41.00infobox
P2RX4Band12q24.311.00infobox
P2RX4Band5 F|5 62.53 cM1.00infobox
P2RX4Bgeemucosa of transverse colon1.00infobox
P2RX4Bgeecerebellar hemisphere1.00infobox
P2RX4Bgeeright hemisphere of cerebellum1.00infobox
P2RX4Bgeegranulocyte1.00infobox
P2RX4Bgeebody of pancreas1.00infobox
P2RX4Bgeemucosa of ileum1.00infobox
P2RX4Bgeemonocyte1.00infobox
P2RX4Bgeerectum1.00infobox
P2RX4Bgeestromal cell of endometrium1.00infobox
P2RX4Bgeemucosa of sigmoid colon1.00infobox
P2RX4BgeeIleal epithelium1.00infobox
P2RX4Bgeelesser wing of sphenoid bone1.00infobox
P2RX4Bgeeparotid gland1.00infobox
P2RX4Bgeenasal septum1.00infobox
P2RX4Bgeesubmandibular gland1.00infobox
P2RX4Bgeelacrimal gland1.00infobox
P2RX4Bgeestroma of bone marrow1.00infobox
P2RX4Bgeeleft colon1.00infobox
P2RX4Bgeeyolk sac1.00infobox
P2RX4Bgeedecidua1.00infobox
P2RX4BioGPSMore reference expression data1.00infobox
P2RX4Chr.Chromosome 12 (human)1.00infobox
P2RX4Chr.Chromosome 5 (mouse)1.00infobox
P2RX4DatabasesNCBI: entry; OMA: entry1.00infobox
P2RX4End121,234,106 bp1.00infobox
P2RX4End122,867,801 bp1.00infobox
P2RX4EnsemblENSG000001351241.00infobox

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