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Calmodulin: Members & Art

Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of calmodulin. Once bound to Ca2+, calmodulin acts as part of a…

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Calmodulin topic overview

The analysis highlights Members and Art as prominent areas in the source structure around Calmodulin.

Related topics
80
Source areas
6
Connected nodes
86
Extracted relationships
102
Concept neighborhoods
30
Bridge connections
86

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 39 topics
Role in animals · 17 topics
Family members · 8 topics
Mechanism · 6 topics
Role in plants · 6 topics
Structure · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
PDB
1OSA
Search for
Search forStructuresSwiss-modelDomainsInterPro
Structures
Swiss-model
Symbol
CaM
UniProt
P62158

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Mechanism

Role in animals

Role in plants

Family members

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Calmodulin connects Entity context

The extracted context around Calmodulin shows recurring relationship patterns in the source. For example, Calmodulin → Archived, Calmodulin Target Database, Chazin, EF-Hand Calcium-Binding Proteins Data, Functional Genomics, Home Page, Ikura, InterPro, IPR015754Proteopedia, Journal, July, Library, Medicine Medical Subject Headings, MeSH, Molecule, Month, Myelin-associated Glycoprotein, National Library, Nelson, Ontario Cancer Institute Another extracted example is Calmodulin → Binding, C-domains, Ca2, Calcium, CaMKII, Canonical, EF-hands, Furthermore, IQ-motif, NaV, SK, The, These, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

Calmodulin

Top relations

related to External links · 28
Calmodulin → Archived, Calmodulin Target Database, Chazin, EF-Hand Calcium-Binding Proteins Data, Functional Genomics, Home Page, Ikura, InterPro, IPR015754Proteopedia, Journal, July, Library, Medicine Medical Subject Headings, MeSH, Molecule, Month, Myelin-associated Glycoprotein, National Library, Nelson, Ontario Cancer Institute
related to Mechanism · 14
Calmodulin → Binding, C-domains, Ca2, Calcium, CaMKII, Canonical, EF-hands, Furthermore, IQ-motif, NaV, SK, The, These, This
related to Structure · 11
Calmodulin → Ca2, EF, EF-hand, EF-hands, However, In, It, N-domain, N-terminus, The, The C-domain
related to Family members · 9
Calmodulin → CALM1, CALM1P1, CALM2, CALM3, CALML3, CALML4, CALML5, CALML6, Calmodulin-like
related to Importance of flexibility in calmodulin · 7
Calmodulin → C-domains, Ca2, Calmodulin's, CaM-binding, In, Moreover, Together
related to Role in plants · 7
Calmodulin → Ca2, Calcium, Calmodulins, CaM, However, The, While
related to Role in animals · 3
Calmodulin → Calcium, It, Many
Domains · 1
Calmodulin → InterPro
PDB · 1
Calmodulin → 1OSA
Search for · 1
Calmodulin → Search forStructuresSwiss-modelDomainsInterPro

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ca2 proteins protein cam binding also target role plants plant calcium response stress cell plays genes growth arabidopsis kinase muscle

Calmodulin relationships Subject–Predicate–Object triples

TTTA extracted 102 structured relationships around Calmodulin. Examples in this analysis include Calmodulin → Domains → InterPro and Calmodulin → PDB → 1OSA. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CalmodulinDomainsInterPro1.00infobox
CalmodulinPDB1OSA1.00infobox
CalmodulinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CalmodulinStructuresSwiss-model1.00infobox
CalmodulinSymbolCaM1.00infobox
CalmodulinUniProtP621581.00infobox
kinases or phosphatasesinstance ofcalmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins0.80text
inflammationinstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
metabolisminstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
apoptosisinstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
smooth muscle contractioninstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
intracellular movementinstance ofRole in animalsCalmodulin mediates many crucial processes0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Calmodulin bring nearby vocabulary together. In this analysis, examples include Target, Protein and Ca2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Calmodulin
    • Target
    • Protein
    • Ca2
    • Binding
    • Calcium
    • Role
    • Contraction
    • Muscle
    • Plays
    • Activation
    • Bound
    • Smooth
  • calmodulin
    • Target
    • Protein
    • Ca2
    • Binding
    • Calcium
    • Role
    • Contraction
    • Muscle
    • Plays
    • Activation
    • Bound
    • Smooth
  • ca2+
    • Binding
    • Calmodulin
    • Protein
    • Levels
    • Also
    • Signaling
    • Cell
    • Response
    • Target
    • Intracellular
    • Calcium
    • Proteins
  • ca2+ channels
    • Binding
    • Calmodulin
    • Protein
    • Levels
    • Also
    • Signaling
    • Cell
    • Response
    • Target
    • Intracellular
    • Calcium
    • Proteins
  • ca2+/calmodulin-dependent protein kinase ii
    • Binding
    • Calmodulin
    • Kinase
    • Protein
    • Tobacco
    • Plays
    • Levels
    • Also
    • Signaling
    • Cell
    • Response
    • Target
  • stress
    • Sorghum
    • Response
    • Plant
    • Development
    • Cam
    • Growth
    • Proteins
    • Expressed
    • Metabolism
    • Also
    • Cmls
    • Defense
  • drought stress
    • Sorghum
    • Response
    • Plant
    • Development
    • Cam
    • Growth
    • Proteins
    • Expressed
    • Metabolism
    • Also
    • Cmls
    • Defense
  • arabidopsis thaliana
    • Plants
    • Development
    • Different
    • Also
    • Growth
    • Genes
    • Proteins
    • Cam
    • Protein
    • Role
    • Metabolism
    • Sorghum

Connections between topic areas Semantic bridges

For Calmodulin, one of the stronger structural bridges in this analysis connects Calmodulin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CalmodulinOverview · splits 47 ⟂ 40
CalmodulinRole in animals · splits 69 ⟂ 18
CalmodulinFamily members · splits 78 ⟂ 9
CalmodulinMechanism · splits 80 ⟂ 7
CalmodulinRole in plants · splits 80 ⟂ 7
CalmodulinStructure · splits 82 ⟂ 5

Map overview Semantic statistics

Calmodulin

Nodes87
Edges86
Triples102
Avg. degree1.98
Density0.022989
Components1

Source & methodology

TTTA analyzes the structure around Calmodulin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Calmodulin · EN edition · Analysis: TopicsToTalkAbout

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