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Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of calmodulin. Once bound to Ca2+, calmodulin acts as part of a…
The analysis highlights Members and Art as prominent areas in the source structure around Calmodulin.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
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The extracted context around Calmodulin shows recurring relationship patterns in the source. For example, Calmodulin → Binding, C-domains, Ca2, Calcium, CaMKII, Canonical, EF-hands, Furthermore, IQ-motif, NaV, SK Another extracted example is Calmodulin → CALM1, CALM1P1, CALM2, CALM3, CALML3, CALML4, CALML5, CALML6, Calmodulin-like. Use these groups to spot repeated connection types before inspecting the individual relationships.
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TTTA extracted 62 structured relationships around Calmodulin. Examples in this analysis include Calmodulin → Domains → InterPro and Calmodulin → PDB → 1OSA. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Calmodulin | Domains | InterPro | 1.00 | infobox |
| Calmodulin | PDB | 1OSA | 1.00 | infobox |
| Calmodulin | Search for | Search forStructuresSwiss-modelDomainsInterPro | 1.00 | infobox |
| Calmodulin | Structures | Swiss-model | 1.00 | infobox |
| Calmodulin | Symbol | CaM | 1.00 | infobox |
| Calmodulin | UniProt | P62158 | 1.00 | infobox |
| kinases or phosphatases | instance of | calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins | 0.80 | text |
| inflammation | instance of | Role in animalsCalmodulin mediates many crucial processes | 0.80 | text |
| metabolism | instance of | Role in animalsCalmodulin mediates many crucial processes | 0.80 | text |
| apoptosis | instance of | Role in animalsCalmodulin mediates many crucial processes | 0.80 | text |
| smooth muscle contraction | instance of | Role in animalsCalmodulin mediates many crucial processes | 0.80 | text |
| intracellular movement | instance of | Role in animalsCalmodulin mediates many crucial processes | 0.80 | text |
The concept neighborhoods around Calmodulin bring nearby vocabulary together. In this analysis, examples include Target, Protein and Ca2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Calmodulin, one of the stronger structural bridges in this analysis connects Calmodulin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Calmodulin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Calmodulin · EN edition · Analysis: TopicsToTalkAbout