Calmodulin

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Role in animals

Inflammation Metabolism Apoptosis Smooth muscle Short-term

17 related topics

Overview

Eukaryotic cells Secondary messenger Ca2+Signal transduction pathway Kinases

39 related topics

Family members

Calmodulin 1 Calmodulin 2 Calmodulin 3 Calmodulin 1 pseudogene 1 Calmodulin-like 3

8 related topics

Mechanism

CaMKII NaV channels IQ-motif Cooperativity Cooperative binding

6 related topics

Key facts & relationships

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Domains: InterPro
PDB: 1OSA
Search for: Search forStructuresSwiss-modelDomainsInterPro
Structures: Swiss-model
Symbol: CaM
UniProt: P62158

Topics to explore

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Overview

Eukaryotic cells Eukaryote
Secondary messenger Second messenger system
Ca2+ Calcium in biology
Signal transduction pathway Signal transduction
Kinases Kinase
Phosphatases Phosphatase
Excitation contraction (EC) coupling Excitation contraction coupling
Smooth muscle Smooth muscle tissue
Myosin light chain
Myosin light chain (MLC) kinase Myosin light-chain kinase
Sarcoplasmic reticulum
Ca2+ channels Calcium channels
Ryanodine receptor
Endoplasmic reticulum
Blood pressure
Phosphorylase kinase
Glucose
Glycogen
Glycogen phosphorylase
Lipid metabolism
Calcitonin Calcitonin gene-related peptide
Gs protein G protein
Ca2+/calmodulin-dependent protein kinase II
Long-term potentiation
Phosphorylation
AMPA receptor
Rhizobium
Nod factor
Medicago
Tobacco

Structure

Mechanism

Role in animals

Role in plants

Family members

Calmodulin 1
Calmodulin 2 CALM2
Calmodulin 3 CALM3
Calmodulin 1 pseudogene 1 CALM1P1?action=edit&redlink=1
Calmodulin-like 3 CALML3
Calmodulin-like 4 CALML4?action=edit&redlink=1
Calmodulin-like 5 CALML5
Calmodulin-like 6 CALML6?action=edit&redlink=1

Advanced semantic analysis

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Map overview Semantic statistics

Nodes87

Edges86

Triples102

Avg. degree1.98

Density0.022989

Components1

How this topic connects Entity context

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Calmodulin

Top relations

related to External links · 28

Calmodulin → Archived, Calmodulin Target Database, Chazin, EF-Hand Calcium-Binding Proteins Data, Functional Genomics, Home Page, Ikura, InterPro, IPR015754Proteopedia, Journal, July, Library, Medicine Medical Subject Headings, MeSH, Molecule, Month, Myelin-associated Glycoprotein, National Library, Nelson, Ontario Cancer Institute

related to Mechanism · 14

Calmodulin → Binding, C-domains, Ca2, Calcium, CaMKII, Canonical, EF-hands, Furthermore, IQ-motif, NaV, SK, The, These, This

related to Structure · 11

Calmodulin → Ca2, EF, EF-hand, EF-hands, However, In, It, N-domain, N-terminus, The, The C-domain

related to Family members · 9

Calmodulin → CALM1, CALM1P1, CALM2, CALM3, CALML3, CALML4, CALML5, CALML6, Calmodulin-like

related to Importance of flexibility in calmodulin · 7

Calmodulin → C-domains, Ca2, Calmodulin's, CaM-binding, In, Moreover, Together

related to Role in plants · 7

Calmodulin → Ca2, Calcium, Calmodulins, CaM, However, The, While

related to Role in animals · 3

Calmodulin → Calcium, It, Many

Domains · 1

Calmodulin → InterPro

PDB · 1

Calmodulin → 1OSA

Search for · 1

Calmodulin → Search forStructuresSwiss-modelDomainsInterPro

Important terminology Word statistics

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Important terminology

ca2 proteins protein cam binding also target role plants plant calcium response stress cell plays genes growth arabidopsis kinase muscle

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Calmodulin	Domains	InterPro	1.00	infobox
Calmodulin	PDB	1OSA	1.00	infobox
Calmodulin	Search for	Search forStructuresSwiss-modelDomainsInterPro	1.00	infobox
Calmodulin	Structures	Swiss-model	1.00	infobox
Calmodulin	Symbol	CaM	1.00	infobox
Calmodulin	UniProt	P62158	1.00	infobox
kinases or phosphatases	instance of	calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins	0.80	text
inflammation	instance of	Role in animalsCalmodulin mediates many crucial processes	0.80	text
metabolism	instance of	Role in animalsCalmodulin mediates many crucial processes	0.80	text
apoptosis	instance of	Role in animalsCalmodulin mediates many crucial processes	0.80	text
smooth muscle contraction	instance of	Role in animalsCalmodulin mediates many crucial processes	0.80	text
intracellular movement	instance of	Role in animalsCalmodulin mediates many crucial processes	0.80	text

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