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Calmodulin: Members & Art

Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of calmodulin. Once bound to Ca2+, calmodulin acts as part of a…

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Calmodulin topic overview

The analysis highlights Members and Art as prominent areas in the source structure around Calmodulin.

Related topics
76
Source areas
6
Connected nodes
82
Extracted relationships
62
Related term clusters
30
Bridge connections
82

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 39 topics
Role in animals · 17 topics
Mechanism · 6 topics
Family members · 5 topics
Role in plants · 5 topics
Structure · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
PDB
1OSA
Search for
Search forStructuresSwiss-modelDomainsInterPro
Structures
Swiss-model
Symbol
CaM
UniProt
P62158

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Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Mechanism

Role in animals

Role in plants

Family members

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How Calmodulin connects Entity context

The extracted context around Calmodulin shows recurring relationship patterns in the source. For example, Calmodulin → Binding, C-domains, Ca2, Calcium, CaMKII, Canonical, EF-hands, Furthermore, IQ-motif, NaV, SK Another extracted example is Calmodulin → CALM1, CALM1P1, CALM2, CALM3, CALML3, CALML4, CALML5, CALML6, Calmodulin-like. Use these groups to spot repeated connection types before inspecting the individual relationships.

Calmodulin

Top relations

related to Mechanism · 11
Calmodulin → Binding, C-domains, Ca2, Calcium, CaMKII, Canonical, EF-hands, Furthermore, IQ-motif, NaV, SK
related to Family members · 9
Calmodulin → CALM1, CALM1P1, CALM2, CALM3, CALML3, CALML4, CALML5, CALML6, Calmodulin-like
related to Structure · 7
Calmodulin → Ca2, EF, EF-hand, EF-hands, N-domain, N-terminus, The C-domain
related to Importance of flexibility in calmodulin · 6
Calmodulin → C-domains, Ca2, Calmodulin's, CaM-binding, Moreover, Together
related to Role in plants · 4
Calmodulin → Ca2, Calcium, Calmodulins, CaM
related to Role in animals · 2
Calmodulin → Calcium, Many
Domains · 1
Calmodulin → InterPro
PDB · 1
Calmodulin → 1OSA
Search for · 1
Calmodulin → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Calmodulin → Swiss-model

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

ca2 proteins protein cam binding also target role plants plant calcium response stress cell plays genes growth arabidopsis kinase muscle

Calmodulin relationships Subject–Predicate–Object triples

TTTA extracted 62 structured relationships around Calmodulin. Examples in this analysis include Calmodulin → Domains → InterPro and Calmodulin → PDB → 1OSA. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CalmodulinDomainsInterPro1.00infobox
CalmodulinPDB1OSA1.00infobox
CalmodulinSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CalmodulinStructuresSwiss-model1.00infobox
CalmodulinSymbolCaM1.00infobox
CalmodulinUniProtP621581.00infobox
kinases or phosphatasesinstance ofcalmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins0.80text
inflammationinstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
metabolisminstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
apoptosisinstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
smooth muscle contractioninstance ofRole in animalsCalmodulin mediates many crucial processes0.80text
intracellular movementinstance ofRole in animalsCalmodulin mediates many crucial processes0.80text

Related concept clusters Related term clusters

The concept neighborhoods around Calmodulin bring nearby vocabulary together. In this analysis, examples include Target, Protein and Ca2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Calmodulin
    • Target
    • Protein
    • Ca2
    • Binding
    • Calcium
    • Role
    • Contraction
    • Muscle
    • Plays
    • Activation
    • Bound
    • Smooth
  • calmodulin
    • Target
    • Protein
    • Ca2
    • Binding
    • Calcium
    • Role
    • Contraction
    • Muscle
    • Plays
    • Activation
    • Bound
    • Smooth
  • ca2+
    • Binding
    • Calmodulin
    • Protein
    • Levels
    • Also
    • Signaling
    • Cell
    • Response
    • Target
    • Intracellular
    • Calcium
    • Proteins
  • ca2+ channels
    • Binding
    • Calmodulin
    • Protein
    • Levels
    • Also
    • Signaling
    • Cell
    • Response
    • Target
    • Intracellular
    • Calcium
    • Proteins
  • ca2+/calmodulin-dependent protein kinase ii
    • Binding
    • Calmodulin
    • Kinase
    • Protein
    • Tobacco
    • Plays
    • Levels
    • Also
    • Signaling
    • Cell
    • Response
    • Target
  • stress
    • Sorghum
    • Response
    • Plant
    • Development
    • Cam
    • Growth
    • Proteins
    • Expressed
    • Metabolism
    • Also
    • Cmls
    • Defense
  • drought stress
    • Sorghum
    • Response
    • Plant
    • Development
    • Cam
    • Growth
    • Proteins
    • Expressed
    • Metabolism
    • Also
    • Cmls
    • Defense
  • arabidopsis thaliana
    • Plants
    • Development
    • Different
    • Also
    • Growth
    • Genes
    • Proteins
    • Cam
    • Protein
    • Role
    • Metabolism
    • Sorghum

Connections between topic areas Semantic bridges

For Calmodulin, one of the stronger structural bridges in this analysis connects Calmodulin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Calmodulin — Overview · splits 43 ⟂ 40
Calmodulin — Role in animals · splits 65 ⟂ 18
Calmodulin — Mechanism · splits 76 ⟂ 7
Calmodulin — Role in plants · splits 77 ⟂ 6
Calmodulin — Family members · splits 77 ⟂ 6
Calmodulin — Structure · splits 78 ⟂ 5

Map overview Semantic statistics

Calmodulin

Nodes83
Edges82
Triples62
Avg. degree1.98
Density0.024096
Components1

Source & methodology

TTTA analyzes the structure around Calmodulin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members & Art, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Calmodulin · EN edition · Analysis: TopicsToTalkAbout

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