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Cyclin

Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK).

History, Function & Types

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Key facts & relationships

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AlphaFold
IPR006671 · PF00134
Available protein structures:
IPR006671 · PF00134
InterPro
IPR006671
PDB
1bu2​, 1e9h​, 1f5q​, 1fin​, 1fvv​, 1g3n​, 1gy3​, 1h1p​, 1h1q​, 1h1r​, 1h1s​, 1h24​, 1h25​, 1h26​, 1h27​, 1h28​, 1jkw​, 1jow​, 1jst​, 1jsu​, 1kxu​, 1ogu​, 1oi9​, 1oiu​, 1oiy​, 1o…
Pfam
PF00134
Pfam clan
CL0065

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Overview

Etymology

Function

Domain structure

Types

Other proteins containing this domain

  • CNTD1 CNTD1?action=edit&redlink=1

History

Advanced semantic analysis

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Map overview Semantic statistics

Cyclin

Nodes47
Edges46
Triples74
Avg. degree1.96
Density0.042553
Components1

How this topic connects Entity context

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Cyclin

Top relations

related to Types · 12
Cyclin → A-deficient, As, Cdk, Cells, Consequently, For, G2/M, In, Notably, Protein, The, There
related to Function · 11
Cyclin → Cdk, Cdks, Complex, Cyclins, G1, G1/S, MPFs, Note, The, These, This
related to Main groups · 10
Cyclin → CDK1, CDK2, CDK4, CDK6, G1, G1/S, G2, G2/M, M-phase, There
related to Etymology · 8
Cyclin → As, Cyclins, December, In, It, Jim Al-Khalili, The Life Scientific, Timothy Hunt
related to history · 8
Cyclin → Hartwell, Leland, Medicine, Nobel Prize, Nurse, Paul, Physiology, Timothy Hunt
related to Domain structure · 7
Cyclin → All, C-terminus, Cyclins, For, However, N-terminus, The
AlphaFold · 2
Cyclin → IPR006671, PF00134
Available protein structures: · 2
Cyclin → IPR006671, PF00134
related to Other proteins containing this domain · 2
Cyclin → CNTD1, In
related to Subtypes · 2
Cyclin → CDK, The

Important terminology Word statistics

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Important terminology

cyclins cell cycle cdk phase cells mitosis g1 proteins structure microtubule g2 kinetochores protein timothy hunt complex active specific division

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CyclinAlphaFoldIPR0066711.00infobox
CyclinAlphaFoldPF001341.00infobox
CyclinAvailable protein structures:IPR0066711.00infobox
CyclinAvailable protein structures:PF001341.00infobox
CyclinInterProIPR0066711.00infobox
CyclinPDB1bu2​, 1e9h​, 1f5q​, 1fin​, 1fvv​, 1g3n​, 1gy3​, 1h1p​, 1h1q​, 1h1r​, 1h1s​, 1h24​, 1h25​, 1h26​, 1h27​, 1h28​, 1jkw​, 1jow​, 1jst​, 1jsu​, 1kxu​, 1ogu​, 1oi9​, 1oiu​, 1oiy​, 1o…1.00infobox
CyclinPfamPF001341.00infobox
CyclinPfam clanCL00651.00infobox
CyclinPROSITEPDOC002641.00infobox
CyclinSCOP21vin / SCOPe / SUPFAM1.00infobox
CyclinSymbolCyclin_N1.00infobox
microtubule formationinstance ofare responsible for specific events during cell division0.80text

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