Cyclin-dependent kinase 1

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Cyclin-dependent kinase 1 topic overview

The analysis highlights Interactions, Structure and Function as prominent areas in the source structure around Cyclin-dependent kinase 1.

Related topics: 29
Source areas: 5
Connected nodes: 34
Extracted relationships: 160
Concept neighborhoods: 11
Bridge connections: 34

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 12 topics

Overview · 8 topics

Structure · 4 topics

Function · 3 topics

Regulation · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.22: ↗
2.7.11.23: ↗
Aliases: CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YC6, 4Y72, 5HQ0, 4YC3
Band: 10q21.2 · 10 B5.3|10 36.07 cM
Bgee: ventricular zone · ganglionic eminence · trabecular bone · secondary oocyte · gonad

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Protein
Serine/threonine protein kinase
Cell cycle
S. cerevisiae Saccharomyces cerevisiae
S. pombe Schizosaccharomyces pombe
Genes Gene
Cyclin
Phosphorylate Phosphorylation

Structure

Kilodaltons Kilodalton
ATP Adenosine triphosphate
Hydroxyl
Cyclin-dependent kinases Cyclin-dependent kinase

Function

Regulation

Interactions

Interact Protein-protein interaction
BCL2 Bcl-2
CCNB1 Cyclin B1
CCNE1 Cyclin E1
CDKN3
DAB2
FANCC Fanconi anemia, complementation group C
GADD45A
LATS1
LYN
P53
UBC Ubiquitin C

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cyclin-dependent kinase 1 connects Entity context

The extracted context around Cyclin-dependent kinase 1 shows recurring relationship patterns in the source. For example, Cyclin-dependent kinase 1 → anaphase-promoting complex-dependent catabolic process, animal organ regeneration, apoptotic process, ATP binding, cell cycle, cell division, cell migration, cell population proliferation, cellular response to hydrogen peroxide, centrosome, centrosome cycle, chromatin binding, chromosome condensation, ciliary basal body-plasma membrane docking, cyclin B1-CDK1 complex, cyclin binding, cyclin-dependent protein kinase activity, cyclin-dependent protein kinase holoenzyme complex, cyclin-dependent protein serine/threonine kinase activity, cytoplasm Another extracted example is Cyclin-dependent kinase 1 → abdominal wall, appendix, bone marrow, cartilage tissue, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, mandibular prominence, maxillary prominence, medial ganglionic eminence, morula, rectum, secondary oocyte, somite, tibia, trabecular bone, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 92

Cyclin-dependent kinase 1 → anaphase-promoting complex-dependent catabolic process, animal organ regeneration, apoptotic process, ATP binding, cell cycle, cell division, cell migration, cell population proliferation, cellular response to hydrogen peroxide, centrosome, centrosome cycle, chromatin binding, chromosome condensation, ciliary basal body-plasma membrane docking, cyclin B1-CDK1 complex, cyclin binding, cyclin-dependent protein kinase activity, cyclin-dependent protein kinase holoenzyme complex, cyclin-dependent protein serine/threonine kinase activity, cytoplasm

Bgee · 18

Cyclin-dependent kinase 1 → abdominal wall, appendix, bone marrow, cartilage tissue, epiblast, fetal liver hematopoietic progenitor cell, ganglionic eminence, gonad, mandibular prominence, maxillary prominence, medial ganglionic eminence, morula, rectum, secondary oocyte, somite, tibia, trabecular bone, ventricular zone

RNA expression pattern · 18

related to External links · 6

Cyclin-dependent kinase 1 → Cyclin-dependent, Overview, P06493, PDB, PDBe-KB, UniProt

Band · 2

Cyclin-dependent kinase 1 → 10 B5.3|10 36.07 cM, 10q21.2

Chr. · 2

Cyclin-dependent kinase 1 → Chromosome 10 (human), Chromosome 10 (mouse)

End · 2

Cyclin-dependent kinase 1 → 60,794,852 bp, 69,188,768 bp

2.7.11.22 · 1

Cyclin-dependent kinase 1 → ↗

2.7.11.23 · 1

Cyclin-dependent kinase 1 → ↗

Aliases · 1

Cyclin-dependent kinase 1 → CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cdk1 cyclin activity phosphorylation cell cycle human cyclins leads kinase yeast bp complexes sic1 protein chr band cyclin-dependent also binding

Cyclin-dependent kinase 1 relationships Subject–Predicate–Object triples

TTTA extracted 160 structured relationships around Cyclin-dependent kinase 1. Examples in this analysis include Cyclin-dependent kinase 1 → 2.7.11.22 → ↗ and Cyclin-dependent kinase 1 → Aliases → CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Cyclin-dependent kinase 1	2.7.11.22	↗	1.00	infobox
Cyclin-dependent kinase 1	2.7.11.23	↗	1.00	infobox
Cyclin-dependent kinase 1	Aliases	CDK1, CDC2, CDC28A, P34CDC2, cyclin-dependent kinase 1, cyclin dependent kinase 1	1.00	infobox
Cyclin-dependent kinase 1	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YC6, 4Y72, 5HQ0, 4YC3	1.00	infobox
Cyclin-dependent kinase 1	Band	10q21.2	1.00	infobox
Cyclin-dependent kinase 1	Band	10 B5.3\|10 36.07 cM	1.00	infobox
Cyclin-dependent kinase 1	Bgee	ventricular zone	1.00	infobox
Cyclin-dependent kinase 1	Bgee	ganglionic eminence	1.00	infobox
Cyclin-dependent kinase 1	Bgee	trabecular bone	1.00	infobox
Cyclin-dependent kinase 1	Bgee	secondary oocyte	1.00	infobox
Cyclin-dependent kinase 1	Bgee	gonad	1.00	infobox
Cyclin-dependent kinase 1	Bgee	rectum	1.00	infobox
Cyclin-dependent kinase 1	Bgee	bone marrow	1.00	infobox
Cyclin-dependent kinase 1	Bgee	tibia	1.00	infobox
Cyclin-dependent kinase 1	Bgee	appendix	1.00	infobox
Cyclin-dependent kinase 1	Bgee	cartilage tissue	1.00	infobox
Cyclin-dependent kinase 1	Bgee	maxillary prominence	1.00	infobox
Cyclin-dependent kinase 1	Bgee	mandibular prominence	1.00	infobox
Cyclin-dependent kinase 1	Bgee	morula	1.00	infobox
Cyclin-dependent kinase 1	Bgee	fetal liver hematopoietic progenitor cell	1.00	infobox
Cyclin-dependent kinase 1	Bgee	epiblast	1.00	infobox
Cyclin-dependent kinase 1	Bgee	medial ganglionic eminence	1.00	infobox
Cyclin-dependent kinase 1	Bgee	abdominal wall	1.00	infobox
Cyclin-dependent kinase 1	Bgee	somite	1.00	infobox
Cyclin-dependent kinase 1	BioGPS	More reference expression data	1.00	infobox
Cyclin-dependent kinase 1	Chr.	Chromosome 10 (human)	1.00	infobox
Cyclin-dependent kinase 1	Chr.	Chromosome 10 (mouse)	1.00	infobox
Cyclin-dependent kinase 1	Databases	NCBI: entry; OMA: entry	1.00	infobox
Cyclin-dependent kinase 1	End	60,794,852 bp	1.00	infobox
Cyclin-dependent kinase 1	End	69,188,768 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cyclin-dependent kinase 1 bring nearby vocabulary together. In this analysis, examples include Kinase, Regulation and Cyclin. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Cyclin-dependent kinase 1
- Kinase
- Regulation
- Cyclin
- Location
- Serine
- Threonine
- Cell
- Cycle
- Chromosome
- Conserved
- Gene
- Highly
cyclin-dependent kinase 1
- Kinase
- Regulation
- Cyclin
- Location
- Protein
- Serine
- Threonine
- Cell
- Cycle
- Chromosome
- Conserved
- Gene
serine/threonine protein kinase
- Serine
- Threonine
- Conserved
- Highly
- Regulation
- Cyclin
- Cyclin-dependent
- Protein
- Atp
- Kinase
- Location
- Activity
cell cycle
- Cycle
- Progression
- Highly
- Cyclin
- Cyclin-dependent
- Complexes
- Kinase
- Budding
- Partners
- Serine
- Threonine
- Phosphorylation
cyclin
- Binding
- Cyclin-dependent
- Kinase
- Partners
- Activity
- Location
- Phosphorylation
- Chromosome
- Gene
- Regulation
- Bp
- Chr
atp
- Conserved
- Kinase
- Location
- Phosphorylation
- Serine
- Threonine
- Band
- Chromosome
- Gene
- Highly
- Regulation
- Spindle
cyclin-dependent kinases
- Kinase
- Regulation
- Cyclin
- Location
- Serine
- Threonine
- Cell
- Cycle
- Chromosome
- Conserved
- Gene
- Highly
protein
- Serine
- Threonine
- Regulation
- Atp
- Location
- Band
- Chromosome
- Gene
- Spindle
- Bp
- Chr
- Entry

Connections between topic areas Semantic bridges

For Cyclin-dependent kinase 1, one of the stronger structural bridges in this analysis connects Cyclin-dependent kinase 1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Cyclin-dependent kinase 1 — Interactions · splits 22 ⟂ 13

Cyclin-dependent kinase 1 — Overview · splits 26 ⟂ 9

Cyclin-dependent kinase 1 — Structure · splits 30 ⟂ 5

Cyclin-dependent kinase 1 — Function · splits 31 ⟂ 4

Cyclin-dependent kinase 1 — Regulation · splits 32 ⟂ 3

Map overview Semantic statistics

Cyclin-dependent kinase 1

Nodes35

Edges34

Triples160

Avg. degree1.94

Density0.057143

Components1

Source & methodology

TTTA analyzes the structure around Cyclin-dependent kinase 1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions, Structure & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cyclin-dependent kinase 1 · EN edition · Analysis: TopicsToTalkAbout