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Furosemide

Furosemide, sold under the brand name Lasix among others, is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease. Furosemide may also be used for the treatment of high blood pressure. It can be taken intravenously or orally. When given intravenously, furosemide typically takes effect within five minutes…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C03CA01 (WHO)
Bioavailability
43–69%
CAS Number
54-31-9
ChEBI
CHEBI:47426

Topics to explore

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Overview

Medical uses

Adverse effects

Interactions

Mechanism of action

Pharmacokinetics

Names

  • INN International Nonproprietary Name
  • BAN British Approved Name

Veterinary uses

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Map overview Semantic statistics

Furosemide

Nodes109
Edges108
Triples138
Avg. degree1.98
Density0.018349
Components1

How this topic connects Entity context

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Furosemide

Top relations

related to Names · 52
Furosemide → Aisemide, Apo-Furosemide, BAN, Beronald, Brand, Desdemin, Discoid, Diural, Diurapid, Dryptal, Durafurid, Edemid, Errolon, Eutensin, Farsiretic, Flusapex, Frudix, Frusemide, Frusetic, Frusid
related to Veterinary uses · 11
Furosemide → Although, America, Clinical, In, Its, New York, Some, Sometime, The, United States, USA
related to Pharmacokinetics · 9
Furosemide → Bioavailability, Excreted, Intravenous, L/kg, Molecular, Prolonged, Protein, The, Time
related to Mechanism of action · 7
Furosemide → Because, Cl, Henle, Na, Na-K-2Cl, NaCl, The
related to Medical uses · 6
Furosemide → Compared, Current, However, It, IV, Torsemide
Legal status · 5
Furosemide → AU: S4 (Prescription only), EU: Rx-only, In general: ℞ (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Other information · 5
Furosemide → Diuresis, In, It, IV, Lower
has effect · 4
Furosemide → Co-amilofruse, Hyperglycemia, Other, The
related to Interactions · 3
Furosemide → Aspirin, Sucralfate, Synergistic
related to External links · 2
Furosemide → Furosemide Injection, MedlinePlus

Important terminology Word statistics

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Important terminology

kidney also effects use used heart failure may blood include edema horses potassium liver loss states side medication pressure loop

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Furosemide3D model (JSmol)Interactive image1.00infobox
FurosemideAHFS/Drugs.comMonograph1.00infobox
FurosemideATC codeC03CA01 (WHO)1.00infobox
FurosemideBioavailability43–69%1.00infobox
FurosemideCAS Number54-31-91.00infobox
FurosemideChEBICHEBI:474261.00infobox
FurosemideChEMBLChEMBL351.00infobox
FurosemideChemSpider33221.00infobox
FurosemideCompTox Dashboard (EPA)DTXSID60206481.00infobox
FurosemideDrugBankDB006951.00infobox
FurosemideECHA InfoCard100.000.1851.00infobox
FurosemideElimination half-lifeup to 100 minutes1.00infobox
FurosemideExcretionKidney (66%), bile duct (33%)1.00infobox
FurosemideFormulaC12H11ClN2O5S1.00infobox
FurosemideKEGGD003311.00infobox
FurosemideLegal statusAU: S4 (Prescription only)1.00infobox
FurosemideLegal statusUK: POM (Prescription only)1.00infobox
FurosemideLegal statusUS: ℞-only1.00infobox
FurosemideLegal statusEU: Rx-only1.00infobox
FurosemideLegal statusIn general: ℞ (Prescription only)1.00infobox
FurosemideLicense dataUS DailyMed: Furosemide1.00infobox
FurosemideMedlinePlusa6828581.00infobox
FurosemideMetabolismLiver and kidney glucuronidation1.00infobox
FurosemideMolar mass330.74 g·mol−11.00infobox
FurosemideOnset of actionPOTooltip Oral administration: 30–60 min, IVTooltip Intravenous therapy: 5 min1.00infobox
FurosemidePregnancy categoryAU: C1.00infobox
FurosemidePronunciation/fjʊˈroʊsəˌmaɪd/1.00infobox
FurosemideProtein binding91–99%1.00infobox
FurosemidePubChem CID34401.00infobox
FurosemideRoutes of administrationOral (PO), intravenous (IV), intramuscular (IM), subcutaneous (SC)1.00infobox

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