Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

MBD1: Interactions & Overview

Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression. It has been shown to play a role in chromatin modification…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

MBD1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around MBD1.

Related topics
10
Source areas
2
Connected nodes
12
Extracted relationships
95
Related term clusters
7
Bridge connections
12

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 5 topics
Overview · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W
Band
18q21.1 · 18 E2|18 50.7 cM
Bgee
left testis · right testis · parotid gland · pituitary gland · anterior pituitary
BioGPS
More reference expression data
Chr.
Chromosome 18 (human) · Chromosome 18 (mouse)

Start with your topic. Discover where to go next.

Explore different angles and find fresh ideas to shape your next piece of content.

MBD1
5Protein · Gene · Methylation
5Protein-protein interaction · ATF7IP · CBX5 (gene)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

For the semantics nerds

You can skip this section if you’re here for content ideas and keyword inspiration.

Advanced semantic analysis

How MBD1 connects Entity context

The extracted context around MBD1 shows recurring relationship patterns in the source. For example, MBD1 → anterior pituitary, lacrimal gland, left colon, left lobe of liver, left ovary, left testis, lobe of prostate, lumbar subsegment of spinal cord, middle temporal gyrus, neural layer of retina, parotid gland, pituitary gland, right lobe of thyroid gland, right ovary, right testis, skin of leg, thymus, tibiofemoral joint, vestibular membrane of cochlear duct Another extracted example is MBD1 → chromosome, DNA binding, DNA methylation-dependent heterochromatin assembly, DNA-binding transcription factor activity, RNA polymerase II-specific, double-stranded methylated DNA binding, metal ion binding, methyl-CpG binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear matrix, nuclear speck, nucleoplasm, nucleus, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, transcription by RNA polymerase II, transcription, DNA-templated, zinc ion binding. Use these groups to spot repeated connection types before inspecting the individual relationships.

MBD1

Top relations

Bgee · 19
MBD1 → anterior pituitary, lacrimal gland, left colon, left lobe of liver, left ovary, left testis, lobe of prostate, lumbar subsegment of spinal cord, middle temporal gyrus, neural layer of retina, parotid gland, pituitary gland, right lobe of thyroid gland, right ovary, right testis, skin of leg, thymus, tibiofemoral joint, vestibular membrane of cochlear duct
Gene ontology · 19
MBD1 → chromosome, DNA binding, DNA methylation-dependent heterochromatin assembly, DNA-binding transcription factor activity, RNA polymerase II-specific, double-stranded methylated DNA binding, metal ion binding, methyl-CpG binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear matrix, nuclear speck, nucleoplasm, nucleus, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, transcription by RNA polymerase II, transcription, DNA-templated, zinc ion binding
RNA expression pattern · 19
MBD1 → anterior pituitary, lacrimal gland, left colon, left lobe of liver, left ovary, left testis, lobe of prostate, lumbar subsegment of spinal cord, middle temporal gyrus, neural layer of retina, parotid gland, pituitary gland, right lobe of thyroid gland, right ovary, right testis, skin of leg, thymus, tibiofemoral joint, vestibular membrane of cochlear duct
related to Function · 11
MBD1 → COOH, CpG, CXXC, DNA, Five, Human, MBD, MBD2, MBD3, MBD4, MECP2
related to Interactions · 4
MBD1 → ATF7IP, CBX5, CHAF1A, SUV39H1
Band · 2
MBD1 → 18 E2|18 50.7 cM, 18q21.1
Chr. · 2
MBD1 → Chromosome 18 (human), Chromosome 18 (mouse)
End · 2
MBD1 → 50,281,774 bp, 74,415,803 bp
Aliases · 1
MBD1 → MBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 1
Available structures · 1
MBD1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene methylated bp protein human chromosome chr band 18 dna transcription domain binding modification location methyl-cpg encoded binds sequences mouse

MBD1 relationships Subject–Predicate–Object triples

TTTA extracted 95 structured relationships around MBD1. Examples in this analysis include MBD1 → Aliases → MBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 1 and MBD1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
MBD1AliasesMBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 11.00infobox
MBD1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W1.00infobox
MBD1Band18q21.11.00infobox
MBD1Band18 E2|18 50.7 cM1.00infobox
MBD1Bgeeleft testis1.00infobox
MBD1Bgeeright testis1.00infobox
MBD1Bgeeparotid gland1.00infobox
MBD1Bgeepituitary gland1.00infobox
MBD1Bgeeanterior pituitary1.00infobox
MBD1Bgeeskin of leg1.00infobox
MBD1Bgeemiddle temporal gyrus1.00infobox
MBD1Bgeeleft ovary1.00infobox
MBD1Bgeeright lobe of thyroid gland1.00infobox
MBD1Bgeeright ovary1.00infobox
MBD1Bgeelacrimal gland1.00infobox
MBD1Bgeelobe of prostate1.00infobox
MBD1Bgeeleft lobe of liver1.00infobox
MBD1Bgeeleft colon1.00infobox
MBD1Bgeeneural layer of retina1.00infobox
MBD1Bgeevestibular membrane of cochlear duct1.00infobox
MBD1Bgeelumbar subsegment of spinal cord1.00infobox
MBD1Bgeetibiofemoral joint1.00infobox
MBD1Bgeethymus1.00infobox
MBD1BioGPSMore reference expression data1.00infobox
MBD1Chr.Chromosome 18 (human)1.00infobox
MBD1Chr.Chromosome 18 (mouse)1.00infobox
MBD1DatabasesNCBI: entry; OMA: entry1.00infobox
MBD1End50,281,774 bp1.00infobox
MBD1End74,415,803 bp1.00infobox
MBD1EnsemblENSG000001416441.00infobox

Related concept clusters Related term clusters

The concept neighborhoods around MBD1 bring nearby vocabulary together. In this analysis, examples include Protein, Gene and Mbd2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • MBD1
    • Protein
    • Gene
    • Mbd2
    • Methyl-cpg
    • Binding
    • Transcription
    • Chromosome
    • Human
    • Methylated
    • Function
    • Mecp2
    • Nuclear
  • mbd1
    • Protein
    • Gene
    • Mbd2
    • Methyl-cpg
    • Binding
    • Transcription
    • Chromosome
    • Human
    • Methylated
    • Function
    • Mecp2
    • Nuclear
  • gene
    • Location
    • Bp
    • Chr
    • Chromosome
    • Human
    • Protein
    • Mbd1
    • E2
    • End
    • Expression
    • Function
    • Methylated
  • methylated
    • Transcription
    • Dna
    • Activity
    • Expression
    • Sequences
    • Binding
    • Protein
    • E2
    • End
    • Function
    • Mbd3
    • Mecp2
  • dna
    • Methylated
    • Binding
    • Transcription
    • Protein
    • Activity
    • E2
    • Encoded
    • End
    • Expression
    • Function
    • Mbd3
    • Mouse
  • transcription
    • Methylated
    • Activity
    • Dna
    • Mbd1
    • Protein
    • Gene
    • Binds
    • E2
    • Encoded
    • End
    • Expression
    • Function
  • protein
    • Function
    • Search
    • Dna
    • Location
    • Methyl-cpg
    • Binding
    • Transcription
    • Bp
    • Chr
    • Chromosome
    • Human
    • Activity

Connections between topic areas Semantic bridges

For MBD1, one of the stronger structural bridges in this analysis connects MBD1 with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
MBD1 — Overview · splits 7 ⟂ 6
MBD1 — Interactions · splits 7 ⟂ 6

Map overview Semantic statistics

MBD1

Nodes13
Edges12
Triples95
Avg. degree1.85
Density0.153846
Components1

Source & methodology

TTTA analyzes the structure around MBD1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — MBD1 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.