Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

MBD1

Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene. The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression. It has been shown to play a role in chromatin modification…

Interactions & Overview

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around MBD1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Interactions

5 related topics

Overview

5 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
MBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W
Band
18q21.1 · 18 E2|18 50.7 cM
Bgee
left testis · right testis · parotid gland · pituitary gland · anterior pituitary
BioGPS
More reference expression data
Chr.
Chromosome 18 (human) · Chromosome 18 (mouse)

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

MBD1

Nodes13
Edges12
Triples97
Avg. degree1.85
Density0.153846
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

MBD1

Top relations

Bgee · 19
MBD1 → anterior pituitary, lacrimal gland, left colon, left lobe of liver, left ovary, left testis, lobe of prostate, lumbar subsegment of spinal cord, middle temporal gyrus, neural layer of retina, parotid gland, pituitary gland, right lobe of thyroid gland, right ovary, right testis, skin of leg, thymus, tibiofemoral joint, vestibular membrane of cochlear duct
Gene ontology · 19
MBD1 → chromosome, DNA binding, DNA methylation-dependent heterochromatin assembly, DNA-binding transcription factor activity, RNA polymerase II-specific, double-stranded methylated DNA binding, metal ion binding, methyl-CpG binding, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, nuclear matrix, nuclear speck, nucleoplasm, nucleus, protein binding, regulation of transcription by RNA polymerase II, regulation of transcription, DNA-templated, transcription by RNA polymerase II, transcription, DNA-templated, zinc ion binding
RNA expression pattern · 19
MBD1 → anterior pituitary, lacrimal gland, left colon, left lobe of liver, left ovary, left testis, lobe of prostate, lumbar subsegment of spinal cord, middle temporal gyrus, neural layer of retina, parotid gland, pituitary gland, right lobe of thyroid gland, right ovary, right testis, skin of leg, thymus, tibiofemoral joint, vestibular membrane of cochlear duct
related to Function · 13
MBD1 → All, COOH, CpG, CXXC, DNA, Each, Five, Human, MBD, MBD2, MBD3, MBD4, MECP2
related to Interactions · 4
MBD1 → ATF7IP, CBX5, CHAF1A, SUV39H1
Band · 2
MBD1 → 18 E2|18 50.7 cM, 18q21.1
Chr. · 2
MBD1 → Chromosome 18 (human), Chromosome 18 (mouse)
End · 2
MBD1 → 50,281,774 bp, 74,415,803 bp
Aliases · 1
MBD1 → MBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 1
Available structures · 1
MBD1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene methylated bp protein human chromosome chr band 18 dna transcription domain binding modification location methyl-cpg encoded binds sequences mouse

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MBD1AliasesMBD1, CXXC3, PCM1, RFT, methyl-CpG binding domain protein 11.00infobox
MBD1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1IG4, 1D9N, 4D4W1.00infobox
MBD1Band18q21.11.00infobox
MBD1Band18 E2|18 50.7 cM1.00infobox
MBD1Bgeeleft testis1.00infobox
MBD1Bgeeright testis1.00infobox
MBD1Bgeeparotid gland1.00infobox
MBD1Bgeepituitary gland1.00infobox
MBD1Bgeeanterior pituitary1.00infobox
MBD1Bgeeskin of leg1.00infobox
MBD1Bgeemiddle temporal gyrus1.00infobox
MBD1Bgeeleft ovary1.00infobox
MBD1Bgeeright lobe of thyroid gland1.00infobox
MBD1Bgeeright ovary1.00infobox
MBD1Bgeelacrimal gland1.00infobox
MBD1Bgeelobe of prostate1.00infobox
MBD1Bgeeleft lobe of liver1.00infobox
MBD1Bgeeleft colon1.00infobox
MBD1Bgeeneural layer of retina1.00infobox
MBD1Bgeevestibular membrane of cochlear duct1.00infobox
MBD1Bgeelumbar subsegment of spinal cord1.00infobox
MBD1Bgeetibiofemoral joint1.00infobox
MBD1Bgeethymus1.00infobox
MBD1BioGPSMore reference expression data1.00infobox
MBD1Chr.Chromosome 18 (human)1.00infobox
MBD1Chr.Chromosome 18 (mouse)1.00infobox
MBD1DatabasesNCBI: entry; OMA: entry1.00infobox
MBD1End50,281,774 bp1.00infobox
MBD1End74,415,803 bp1.00infobox
MBD1EnsemblENSG000001416441.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.