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Explore the main themes, entities and connections around USP7. Start with the topic map, then use the sections below for research and deeper semantic analysis.
Explore this topic
Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.
Function
11 related topics
Binding partners
6 related topics
Clinical significance
6 related topics
Association with herpesviruses
5 related topics
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
- 3.4.19.12
- ↗
- Aliases
- USP7, HAUSP, TEF1, ubiquitin specific peptidase 7 (herpes virus-associated), ubiquitin specific peptidase 7, HAFOUS
- Available structures
- Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1NB8, 1NBF, 1YY6, 1YZE, 2F1W, 2F1X, 2F1Y, 2F1Z, 2FOJ, 2FOO, 2FOP, 2KVR, 2XXN, 2YLM, 3MQR, 3MQS, 4JJQ, 4KG9,…
- Band
- 16p13.2 · 16|16 A1
- Bgee
- Brodmann area 23 · middle temporal gyrus · Achilles tendon · epithelium of colon · ventricular zone
- BioGPS
- More reference expression data
Topics to explore
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.Browse the full topic structure. Each item opens a new analysis centered on that subject.
Overview
Function
- Ubiquitin
- Protease
- Polyubiquitination
- Mdm2
- E3 ubiquitin ligase Ubiquitin ligase
- P53
- Myc
- Histone H2B
- Homeotic Homeotic gene
- Histone H2A
- MAGED1
Association with herpesviruses
Binding partners
Interactions
Clinical significance
Advanced semantic analysis
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
Map overview Semantic statistics
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.USP7
Nodes40
Edges39
Triples158
Avg. degree1.95
Density0.05
Components1
How this topic connects Entity context
Quick relationship hints grouped by predicate. Useful for spotting recurring semantic connections around the current entity.See the strongest relationship patterns around the current topic before diving into the raw triples.
USP7
Top relations
Gene ontology · 42
USP7 → cellular response to DNA damage stimulus, chromosome, cysteine-type endopeptidase activity, cysteine-type peptidase activity, cytoplasm, cytosol, deubiquitinase activity, DNA repair, histone H2B conserved C-terminal lysine deubiquitination, hydrolase activity, Lys48-specific deubiquitinase activity, maintenance of DNA methylation, monoubiquitinated protein deubiquitination, multicellular organism development, negative regulation of NF-kappaB transcription factor activity, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, nuclear body, nucleoplasm, nucleus, p53 binding
Bgee · 19
USP7 → Achilles tendon, Brodmann area 23, epithelium of colon, fetal liver hematopoietic progenitor cell, ganglionic eminence, human fetus, medullary collecting duct, mesenteric lymph nodes, middle temporal gyrus, Paneth cell, primary oocyte, rectum, renal corpuscle, secondary oocyte, skin of abdomen, skin of leg, substantia nigra, ureter, ventricular zone
RNA expression pattern · 19
USP7 → Achilles tendon, Brodmann area 23, epithelium of colon, fetal liver hematopoietic progenitor cell, ganglionic eminence, human fetus, medullary collecting duct, mesenteric lymph nodes, middle temporal gyrus, Paneth cell, primary oocyte, rectum, renal corpuscle, secondary oocyte, skin of abdomen, skin of leg, substantia nigra, ureter, ventricular zone
related to Association with herpesviruses · 18
USP7 → Additionally, Barr, Compromising, E3-ubiquitin, EBNA1, EBV, Epstein, GMPS, H2B, HAUSP, Herpesvirus Associated USP, HSV, ICP0, In, More, Stabilization, This, Thus USP7
related to Role in transcriptional regulation · 9
USP7 → Drosophila, GMP, GMPS, H2A, H2AK119ub1, H2B, Pc, Polycomb-repressive, The USP7-GMPS
related to Regulation of the p53 tumor suppressor · 7
USP7 → E3, HAUSP, In, Mdm2, Mdm2-mediated, Normally, Since
related to Interactions · 6
USP7 → Ataxin, CLSPN, DUBs, H2A, MAGED1, P53
related to Role in drug addiction · 5
USP7 → Furthermore, H2A, Maged1, These, This
related to Binding partners · 3
USP7 → MdmXFOXO4DaxxPTENMarch7UVSSA, The, USP7/HAUSP
related to Clinical significance · 3
USP7 → Hao-Fountain Syndrome, Loss-of-function, MRIs
Important terminology Word statistics
Frequent words and multi-word phrases across the lead, headings, infobox and body. Useful for terminology coverage.Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
Important terminology
p53 hausp human gene ubiquitin bp function chr chromosome band also activity histone oncogenic binding associated degradation 16 enzyme tumor
Entity relationships Subject–Predicate–Object triples
Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| USP7 | 3.4.19.12 | ↗ | 1.00 | infobox |
| USP7 | Aliases | USP7, HAUSP, TEF1, ubiquitin specific peptidase 7 (herpes virus-associated), ubiquitin specific peptidase 7, HAFOUS | 1.00 | infobox |
| USP7 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1NB8, 1NBF, 1YY6, 1YZE, 2F1W, 2F1X, 2F1Y, 2F1Z, 2FOJ, 2FOO, 2FOP, 2KVR, 2XXN, 2YLM, 3MQR, 3MQS, 4JJQ, 4KG9,… | 1.00 | infobox |
| USP7 | Band | 16p13.2 | 1.00 | infobox |
| USP7 | Band | 16|16 A1 | 1.00 | infobox |
| USP7 | Bgee | Brodmann area 23 | 1.00 | infobox |
| USP7 | Bgee | middle temporal gyrus | 1.00 | infobox |
| USP7 | Bgee | Achilles tendon | 1.00 | infobox |
| USP7 | Bgee | epithelium of colon | 1.00 | infobox |
| USP7 | Bgee | ventricular zone | 1.00 | infobox |
| USP7 | Bgee | rectum | 1.00 | infobox |
| USP7 | Bgee | skin of leg | 1.00 | infobox |
| USP7 | Bgee | skin of abdomen | 1.00 | infobox |
| USP7 | Bgee | secondary oocyte | 1.00 | infobox |
| USP7 | Bgee | ganglionic eminence | 1.00 | infobox |
| USP7 | Bgee | renal corpuscle | 1.00 | infobox |
| USP7 | Bgee | medullary collecting duct | 1.00 | infobox |
| USP7 | Bgee | ureter | 1.00 | infobox |
| USP7 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| USP7 | Bgee | primary oocyte | 1.00 | infobox |
| USP7 | Bgee | Paneth cell | 1.00 | infobox |
| USP7 | Bgee | human fetus | 1.00 | infobox |
| USP7 | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| USP7 | Bgee | substantia nigra | 1.00 | infobox |
| USP7 | BioGPS | More reference expression data | 1.00 | infobox |
| USP7 | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| USP7 | Chr. | Chromosome 16 (mouse) | 1.00 | infobox |
| USP7 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| USP7 | End | 8,975,328 bp | 1.00 | infobox |
| USP7 | End | 8,610,172 bp | 1.00 | infobox |
No triples extracted yet.
Related concept clusters Concept neighborhoods
Clusters of nearby vocabulary surrounding the topic. Scan them for adjacent concepts and language you may have missed.These clusters group vocabulary that occurs around closely connected concepts in the source material.
Connections between topic areas Semantic bridges
Bridge nodes connect otherwise separate parts of the map. Expand a row to inspect the topic groups on each side.Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.
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