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Bilastine: Applications, Overview & Chemistry

Bilastine is an antihistamine medication used to treat hives (urticaria), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H1 receptor, preventing these allergic reactions. Bilastine has an effectiveness similar to…

Language: English [EN]
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Bilastine topic overview

The analysis highlights Applications, Overview and Chemistry as prominent areas in the source structure around Bilastine.

Related topics
32
Source areas
5
Connected nodes
37
Extracted relationships
94
Concept neighborhoods
15
Bridge connections
37

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 19 topics
Chemistry · 5 topics
Side effects · 4 topics
Medical uses · 2 topics
Pharmacology · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
ATC code
R06AX29 (WHO) S01GX13 (WHO)
Bioavailability
61%
CAS Number
202189-78-4 Y
ChEMBL
ChEMBL1742423 Y
ChemSpider
161234 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

  • PO Per oral
  • PRN Pro re nata

Side effects

Pharmacology

Chemistry

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Bilastine connects Entity context

The extracted context around Bilastine shows recurring relationship patterns in the source. For example, Bilastine → AR, Drug Administration, ECG, FDA, Food, ICH E14, III, It, Likewise, P-gP, Phase II, QT/QTc, QTc, The, The Thorough QT/QTc, Thorough QT/QTc, When Another extracted example is Bilastine → After, Although, AR, ECG, In, LD50, No, Pharmacokinetic/pharmacodynamic, SAR, Toxicity. Use these groups to spot repeated connection types before inspecting the individual relationships.

Bilastine

Top relations

related to Cardiac safety · 17
Bilastine → AR, Drug Administration, ECG, FDA, Food, ICH E14, III, It, Likewise, P-gP, Phase II, QT/QTc, QTc, The, The Thorough QT/QTc, Thorough QT/QTc, When
has effect · 10
Bilastine → After, Although, AR, ECG, In, LD50, No, Pharmacokinetic/pharmacodynamic, SAR, Toxicity
related to Dosage and administration · 7
Bilastine → Allertine, Australian, Dose, It, PO, PRN, While
related to Interactions · 6
Bilastine → Coadministration, OATP, P-glycoprotein-mediated, P-glycoproteins, Preclinical, This
related to Pharmacodynamics · 6
Bilastine → Corcóstegui, H1-antihistamines, H1-receptors, In, Ki, Preclinical
Legal status · 3
Bilastine → AU: S4 (Prescription only) / Schedule 3; Schedule 2; Appendix H, clause 1, CA: ℞-only, NZ: S2 (Pharmacy Only)
related to Allergic rhinoconjunctivitis · 3
Bilastine → AR, In, The
related to Research · 3
Bilastine → Clinical, Notably, The
is a · 2
Bilastine → antihistamine medication used to treat hives, peripherally selective drug
3D model (JSmol) · 1
Bilastine → Interactive image

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cetirizine urticaria allergic dose mg administration clinical antihistamine studies treatment 20 effects rhinitis patients study oral effect similar trials daily

Bilastine relationships Subject–Predicate–Object triples

TTTA extracted 94 structured relationships around Bilastine. Examples in this analysis include Bilastine → 3D model (JSmol) → Interactive image and Bilastine → ATC code → R06AX29 (WHO) S01GX13 (WHO). The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Bilastine3D model (JSmol)Interactive image1.00infobox
BilastineATC codeR06AX29 (WHO) S01GX13 (WHO)1.00infobox
BilastineBioavailability61%1.00infobox
BilastineCAS Number202189-78-4 Y1.00infobox
BilastineChEMBLChEMBL1742423 Y1.00infobox
BilastineChemSpider161234 Y1.00infobox
BilastineCompTox Dashboard (EPA)DTXSID50576781.00infobox
BilastineDrug classAntihistamine1.00infobox
BilastineDrugBankDB115911.00infobox
BilastineDuration of action24 hours (Allertine)1.00infobox
BilastineECHA InfoCard100.260.0161.00infobox
BilastineElimination half-life14.5 hours1.00infobox
BilastineExcretion95% in urine and faeces1.00infobox
BilastineFormulaC28H37N3O31.00infobox
BilastineKEGGD095701.00infobox
BilastineLegal statusAU: S4 (Prescription only) / Schedule 3; Schedule 2; Appendix H, clause 11.00infobox
BilastineLegal statusCA: ℞-only1.00infobox
BilastineLegal statusNZ: S2 (Pharmacy Only)1.00infobox
BilastineMetabolismNot significantly metabolised1.00infobox
BilastineMolar mass463.622 g·mol−11.00infobox
BilastineOnset of action1 hour (Allertine)1.00infobox
BilastinePregnancy categoryAU: B31.00infobox
BilastineProtein binding84-90% binding to plasma proteins1.00infobox
BilastinePubChem CID1854601.00infobox
BilastineRoutes of administrationBy mouth1.00infobox
BilastineTrade namesBlexten, others1.00infobox
BilastineUNIIPA1123N3951.00infobox
Bilastineis aantihistamine medication used to treat hives0.90text
Bilastineis aperipherally selective drug0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Bilastine bring nearby vocabulary together. In this analysis, examples include Urticaria, Clinical and Cetirizine. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Bilastine
    • Urticaria
    • Clinical
    • Cetirizine
    • Mg
    • Administration
    • Interval
    • Qtc
    • Similar
    • Trials
    • Allergic
    • Patients
    • Study
  • bilastine
    • Urticaria
    • Clinical
    • Cetirizine
    • Mg
    • Administration
    • Interval
    • Qtc
    • Similar
    • Trials
    • Allergic
    • Patients
    • Study
  • urticaria
    • Trials
    • Allergic
    • Patients
    • Clinical
    • Rhinitis
    • Efficacy
    • Research
    • Safety
    • Antihistamine
    • Bilastine
    • Administration
    • Metabolism
  • european academy of allergy and clinical immunology
    • Trials
    • Patients
    • Safety
    • Adverse
    • Urticaria
    • Rhinitis
    • Although
    • Drug
    • Research
    • Similar
    • Study
    • Administration
  • chronic idiopathic urticaria
    • Trials
    • Allergic
    • Patients
    • Clinical
    • Rhinitis
    • Efficacy
    • Research
    • Safety
    • Antihistamine
    • Bilastine
    • Administration
    • Metabolism
  • antihistamine medication
    • Second-generation
    • Allergic
    • Rhinitis
    • Effect
    • Administration
    • Urticaria
    • Metabolism
    • Bilastine
    • Although
    • Drug
    • Efficacy
    • Histamine
  • second-generation antihistamine
    • Second-generation
    • Allergic
    • Rhinitis
    • Effect
    • Administration
    • Urticaria
    • Although
    • Efficacy
    • Metabolism
    • Bilastine
    • Drug
    • Histamine
  • cetirizine
    • Desloratadine
    • Fexofenadine
    • Similar
    • Oral
    • Histamine
    • Sar
    • Effects
    • Clinical
    • Studies
    • Mg
    • Although
    • Efficacy

Connections between topic areas Semantic bridges

For Bilastine, one of the stronger structural bridges in this analysis connects Bilastine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Bilastine — Overview · splits 18 ⟂ 20
Bilastine — Chemistry · splits 32 ⟂ 6
Bilastine — Side effects · splits 33 ⟂ 5
Bilastine — Medical uses · splits 35 ⟂ 3
Bilastine — Pharmacology · splits 35 ⟂ 3

Map overview Semantic statistics

Bilastine

Nodes38
Edges37
Triples94
Avg. degree1.95
Density0.052632
Components1

Source & methodology

TTTA analyzes the structure around Bilastine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Overview & Chemistry, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Bilastine · EN edition · Analysis: TopicsToTalkAbout

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