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Bilastine

Bilastine is an antihistamine medication used to treat hives (urticaria), allergic rhinitis and itchy inflamed eyes (allergic conjunctivitis) caused by an allergy. It is a second-generation antihistamine and takes effect by selectively inhibiting the histamine H1 receptor, preventing these allergic reactions. Bilastine has an effectiveness similar to…

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3D model (JSmol)
Interactive image
ATC code
R06AX29 (WHO) S01GX13 (WHO)
Bioavailability
61%
CAS Number
202189-78-4 Y
ChEMBL
ChEMBL1742423 Y
ChemSpider
161234 Y

Topics to explore

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Overview

Medical uses

  • PO Per oral
  • PRN Pro re nata

Side effects

Pharmacology

Chemistry

Advanced semantic analysis

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Map overview Semantic statistics

Bilastine

Nodes38
Edges37
Triples94
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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Bilastine

Top relations

related to Cardiac safety · 17
Bilastine → AR, Drug Administration, ECG, FDA, Food, ICH E14, III, It, Likewise, P-gP, Phase II, QT/QTc, QTc, The, The Thorough QT/QTc, Thorough QT/QTc, When
has effect · 10
Bilastine → After, Although, AR, ECG, In, LD50, No, Pharmacokinetic/pharmacodynamic, SAR, Toxicity
related to Dosage and administration · 7
Bilastine → Allertine, Australian, Dose, It, PO, PRN, While
related to Interactions · 6
Bilastine → Coadministration, OATP, P-glycoprotein-mediated, P-glycoproteins, Preclinical, This
related to Pharmacodynamics · 6
Bilastine → Corcóstegui, H1-antihistamines, H1-receptors, In, Ki, Preclinical
Legal status · 3
Bilastine → AU: S4 (Prescription only) / Schedule 3; Schedule 2; Appendix H, clause 1, CA: ℞-only, NZ: S2 (Pharmacy Only)
related to Allergic rhinoconjunctivitis · 3
Bilastine → AR, In, The
related to Research · 3
Bilastine → Clinical, Notably, The
is a · 2
Bilastine → antihistamine medication used to treat hives, peripherally selective drug
3D model (JSmol) · 1
Bilastine → Interactive image

Important terminology Word statistics

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Important terminology

cetirizine urticaria allergic dose mg administration clinical antihistamine studies treatment 20 effects rhinitis patients study oral effect similar trials daily

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Bilastine3D model (JSmol)Interactive image1.00infobox
BilastineATC codeR06AX29 (WHO) S01GX13 (WHO)1.00infobox
BilastineBioavailability61%1.00infobox
BilastineCAS Number202189-78-4 Y1.00infobox
BilastineChEMBLChEMBL1742423 Y1.00infobox
BilastineChemSpider161234 Y1.00infobox
BilastineCompTox Dashboard (EPA)DTXSID50576781.00infobox
BilastineDrug classAntihistamine1.00infobox
BilastineDrugBankDB115911.00infobox
BilastineDuration of action24 hours (Allertine)1.00infobox
BilastineECHA InfoCard100.260.0161.00infobox
BilastineElimination half-life14.5 hours1.00infobox
BilastineExcretion95% in urine and faeces1.00infobox
BilastineFormulaC28H37N3O31.00infobox
BilastineKEGGD095701.00infobox
BilastineLegal statusAU: S4 (Prescription only) / Schedule 3; Schedule 2; Appendix H, clause 11.00infobox
BilastineLegal statusCA: ℞-only1.00infobox
BilastineLegal statusNZ: S2 (Pharmacy Only)1.00infobox
BilastineMetabolismNot significantly metabolised1.00infobox
BilastineMolar mass463.622 g·mol−11.00infobox
BilastineOnset of action1 hour (Allertine)1.00infobox
BilastinePregnancy categoryAU: B31.00infobox
BilastineProtein binding84-90% binding to plasma proteins1.00infobox
BilastinePubChem CID1854601.00infobox
BilastineRoutes of administrationBy mouth1.00infobox
BilastineTrade namesBlexten, others1.00infobox
BilastineUNIIPA1123N3951.00infobox
Bilastineis aantihistamine medication used to treat hives0.90text
Bilastineis aperipherally selective drug0.90text

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