Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

DUSP6: Function, Interactions & Overview

Dual specificity phosphatase 6 (DUSP6) is a phosphatase enzyme that is encoded by the DUSP6 gene in humans.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

DUSP6 topic overview

The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around DUSP6.

Related topics
10
Source areas
3
Connected nodes
13
Extracted relationships
93
Concept neighborhoods
8
Bridge connections
13

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 6 topics
Interactions · 2 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3.1.3.16
3.1.3.48
Aliases
DUSP6, HH19, MKP3, PYST1, dual specificity phosphatase 6
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HZM, 1MKP
Band
12q21.33 · 10|10 D1
Bgee
parotid gland · pericardium · monocyte · lactiferous duct · visceral pleura

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DUSP6 connects Entity context

The extracted context around DUSP6 shows recurring relationship patterns in the source. For example, DUSP6 → cell differentiation, cytoplasm, cytosol, dephosphorylation, dorsal/ventral pattern formation, hydrolase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, MAPK cascade, negative regulation of ERK1 and ERK2 cascade, negative regulation of protein phosphorylation, nucleoplasm, peptidyl-tyrosine dephosphorylation, phosphatase activity, phosphoprotein phosphatase activity, positive regulation of apoptotic process, positive regulation of cell death, protein dephosphorylation, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, regulation of endodermal cell fate specification Another extracted example is DUSP6 → atrioventricular valve, endocardial cushion, granulocyte, lactiferous duct, left lung lobe, lower lobe of lung, maxillary prominence, monocyte, parietal pleura, parotid gland, pericardium, retinal pigment epithelium, right lung lobe, stroma of bone marrow, tail of embryo, trachea, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

DUSP6

Top relations

Gene ontology · 26
DUSP6 → cell differentiation, cytoplasm, cytosol, dephosphorylation, dorsal/ventral pattern formation, hydrolase activity, MAP kinase tyrosine/serine/threonine phosphatase activity, MAPK cascade, negative regulation of ERK1 and ERK2 cascade, negative regulation of protein phosphorylation, nucleoplasm, peptidyl-tyrosine dephosphorylation, phosphatase activity, phosphoprotein phosphatase activity, positive regulation of apoptotic process, positive regulation of cell death, protein dephosphorylation, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity, regulation of endodermal cell fate specification
Bgee · 17
DUSP6 → atrioventricular valve, endocardial cushion, granulocyte, lactiferous duct, left lung lobe, lower lobe of lung, maxillary prominence, monocyte, parietal pleura, parotid gland, pericardium, retinal pigment epithelium, right lung lobe, stroma of bone marrow, tail of embryo, trachea, visceral pleura
RNA expression pattern · 17
DUSP6 → atrioventricular valve, endocardial cushion, granulocyte, lactiferous duct, left lung lobe, lower lobe of lung, maxillary prominence, monocyte, parietal pleura, parotid gland, pericardium, retinal pigment epithelium, right lung lobe, stroma of bone marrow, tail of embryo, trachea, visceral pleura
related to Function · 6
DUSP6 → ERK2, MAP, MAPK/ERK, SAPK/JNK, These, They
Band · 2
DUSP6 → 10|10 D1, 12q21.33
Chr. · 2
DUSP6 → Chromosome 10 (mouse), Chromosome 12 (human)
End · 2
DUSP6 → 89,352,501 bp, 99,103,351 bp
3.1.3.16 · 1
DUSP6 → ↗
3.1.3.48 · 1
DUSP6 → ↗
Aliases · 1
DUSP6 → DUSP6, HH19, MKP3, PYST1, dual specificity phosphatase 6

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp phosphatase gene chr human band chromosome 12 dual specificity protein location mouse enzyme function external pdb uniprot q16828 search

DUSP6 relationships Subject–Predicate–Object triples

TTTA extracted 93 structured relationships around DUSP6. Examples in this analysis include DUSP6 → 3.1.3.16 → ↗ and DUSP6 → Aliases → DUSP6, HH19, MKP3, PYST1, dual specificity phosphatase 6. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DUSP63.1.3.161.00infobox
DUSP63.1.3.481.00infobox
DUSP6AliasesDUSP6, HH19, MKP3, PYST1, dual specificity phosphatase 61.00infobox
DUSP6Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1HZM, 1MKP1.00infobox
DUSP6Band12q21.331.00infobox
DUSP6Band10|10 D11.00infobox
DUSP6Bgeeparotid gland1.00infobox
DUSP6Bgeepericardium1.00infobox
DUSP6Bgeemonocyte1.00infobox
DUSP6Bgeelactiferous duct1.00infobox
DUSP6Bgeevisceral pleura1.00infobox
DUSP6Bgeelower lobe of lung1.00infobox
DUSP6Bgeeretinal pigment epithelium1.00infobox
DUSP6Bgeegranulocyte1.00infobox
DUSP6Bgeeparietal pleura1.00infobox
DUSP6Bgeetrachea1.00infobox
DUSP6Bgeeleft lung lobe1.00infobox
DUSP6Bgeestroma of bone marrow1.00infobox
DUSP6Bgeemaxillary prominence1.00infobox
DUSP6Bgeeendocardial cushion1.00infobox
DUSP6Bgeetail of embryo1.00infobox
DUSP6Bgeeatrioventricular valve1.00infobox
DUSP6Bgeeright lung lobe1.00infobox
DUSP6BioGPSMore reference expression data1.00infobox
DUSP6Chr.Chromosome 12 (human)1.00infobox
DUSP6Chr.Chromosome 10 (mouse)1.00infobox
DUSP6DatabasesNCBI: entry; OMA: entry1.00infobox
DUSP6End89,352,501 bp1.00infobox
DUSP6End99,103,351 bp1.00infobox
DUSP6EnsemblENSG000001393181.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DUSP6 bring nearby vocabulary together. In this analysis, examples include Phosphatase, Specificity and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DUSP6
    • Phosphatase
    • Specificity
    • Gene
    • Activity
    • Cytoplasm
    • Enzyme
    • Erk2
    • Expressed
    • Function
    • Heart
    • Search
    • Location
  • dusp6
    • Phosphatase
    • Specificity
    • Gene
    • Activity
    • Cytoplasm
    • Enzyme
    • Erk2
    • Expressed
    • Function
    • Heart
    • Search
    • Location
  • phosphatase
    • Specificity
    • Activity
    • Available
    • Dusp6
    • Enzyme
    • Function
    • Gene
    • Pdb
    • Q16828
    • Search
    • Uniprot
    • Location
  • gene
    • Location
    • Chromosome
    • Human
    • Phosphatase
    • Specificity
    • Bp
    • Chr
    • Activity
    • End
    • Function
    • Mouse
    • Search
  • function
    • Activity
    • Search
    • Location
    • Chromosome
    • Human
    • Phosphatase
    • Specificity
    • Bp
    • Chr
    • Gene
    • Available
    • Cellular
  • erk2
    • Expressed
    • Heart
    • Function
    • Kinase
    • Map
    • Mapk
    • Mouse
    • Q16828
    • Search
    • Threonine
    • Uniprot
    • Location
  • mitogen-activated protein
    • Q16828
    • Uniprot
    • Specificity
    • Search
    • Threonine
  • threonine
    • Q16828
    • Uniprot
    • Specificity

Connections between topic areas Semantic bridges

For DUSP6, one of the stronger structural bridges in this analysis connects DUSP6 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DUSP6Function · splits 7 ⟂ 7
DUSP6Overview · splits 11 ⟂ 3
DUSP6Interactions · splits 11 ⟂ 3

Map overview Semantic statistics

DUSP6

Nodes14
Edges13
Triples93
Avg. degree1.86
Density0.142857
Components1

Source & methodology

TTTA analyzes the structure around DUSP6 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DUSP6 · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.