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MAP2K2

Dual specificity mitogen-activated protein kinase kinase 2 is an enzyme that in humans is encoded by the MAP2K2 gene. It is more commonly known as MEK2, but has many alternative names including CFC4, MKK2, MAPKK2 and PRKMK2.

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4 related topics

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2.7.12.2
Aliases
MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2, mitogen-activated protein kinase kinase 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S9I, 4H3Q
Band
19p13.3 · 10 C1|10 39.72 cM
Bgee
mucosa of transverse colon · right testis · left testis · apex of heart · muscle of thigh
BioGPS
More reference expression data

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MAP2K2

Nodes12
Edges11
Triples115
Avg. degree1.83
Density0.166667
Components1

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MAP2K2

Top relations

Gene ontology · 50
MAP2K2 → activation of protein kinase activity, ATP binding, cell-cell junction, cytoplasm, cytoplasmic side of plasma membrane, cytosol, early endosome, endoplasmic reticulum, ERK1 and ERK2 cascade, extracellular region, focal adhesion, Golgi apparatus, kinase activity, late endosome, MAP kinase kinase activity, MAPK cascade, membrane, metal ion binding, microtubule, mitochondrion
Bgee · 19
MAP2K2 → anterior pituitary, apex of heart, duodenum, esophagus, gastrocnemius muscle, left testis, lip, mucosa of transverse colon, muscle of thigh, neural tube, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right testis, Rostral migratory stream, superior frontal gyrus, ventricular zone, yolk sac
RNA expression pattern · 19
MAP2K2 → anterior pituitary, apex of heart, duodenum, esophagus, gastrocnemius muscle, left testis, lip, mucosa of transverse colon, muscle of thigh, neural tube, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right testis, Rostral migratory stream, superior frontal gyrus, ventricular zone, yolk sac
Band · 2
MAP2K2 → 10 C1|10 39.72 cM, 19p13.3
Chr. · 2
MAP2K2 → Chromosome 10 (mouse), Chromosome 19 (human)
End · 2
MAP2K2 → 4,124,122 bp, 80,969,809 bp
related to Interactions · 2
MAP2K2 → ARAF, MAPK3
2.7.12.2 · 1
MAP2K2 → ↗
Aliases · 1
MAP2K2 → MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2, mitogen-activated protein kinase kinase 2
Available structures · 1
MAP2K2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S9I, 4H3Q

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Important terminology

kinase bp gene chr human band protein chromosome 19 mitogen-activated location dual specificity enzyme mouse map mek2 cfc4 mkk2 mapkk2

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MAP2K22.7.12.21.00infobox
MAP2K2AliasesMAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2, mitogen-activated protein kinase kinase 21.00infobox
MAP2K2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S9I, 4H3Q1.00infobox
MAP2K2Band19p13.31.00infobox
MAP2K2Band10 C1|10 39.72 cM1.00infobox
MAP2K2Bgeemucosa of transverse colon1.00infobox
MAP2K2Bgeeright testis1.00infobox
MAP2K2Bgeeleft testis1.00infobox
MAP2K2Bgeeapex of heart1.00infobox
MAP2K2Bgeemuscle of thigh1.00infobox
MAP2K2Bgeegastrocnemius muscle1.00infobox
MAP2K2Bgeeright frontal lobe1.00infobox
MAP2K2Bgeeanterior pituitary1.00infobox
MAP2K2Bgeeright hemisphere of cerebellum1.00infobox
MAP2K2Bgeeprefrontal cortex1.00infobox
MAP2K2Bgeelip1.00infobox
MAP2K2Bgeeright kidney1.00infobox
MAP2K2Bgeeyolk sac1.00infobox
MAP2K2Bgeeneural tube1.00infobox
MAP2K2Bgeeventricular zone1.00infobox
MAP2K2Bgeeduodenum1.00infobox
MAP2K2Bgeeesophagus1.00infobox
MAP2K2Bgeesuperior frontal gyrus1.00infobox
MAP2K2BgeeRostral migratory stream1.00infobox
MAP2K2BioGPSMore reference expression data1.00infobox
MAP2K2Chr.Chromosome 19 (human)1.00infobox
MAP2K2Chr.Chromosome 10 (mouse)1.00infobox
MAP2K2DatabasesNCBI: entry; OMA: entry1.00infobox
MAP2K2End4,124,122 bp1.00infobox
MAP2K2End80,969,809 bp1.00infobox

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