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Dual specificity mitogen-activated protein kinase kinase 2 is an enzyme that in humans is encoded by the MAP2K2 gene. It is more commonly known as MEK2, but has many alternative names including CFC4, MKK2, MAPKK2 and PRKMK2.
The analysis highlights Function, Interactions and Overview as prominent areas in the source structure around MAP2K2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around MAP2K2 shows recurring relationship patterns in the source. For example, MAP2K2 → activation of protein kinase activity, ATP binding, cell-cell junction, cytoplasm, cytoplasmic side of plasma membrane, cytosol, early endosome, endoplasmic reticulum, ERK1 and ERK2 cascade, extracellular region, focal adhesion, Golgi apparatus, kinase activity, late endosome, MAP kinase kinase activity, MAPK cascade, membrane, metal ion binding, microtubule, mitochondrion Another extracted example is MAP2K2 → anterior pituitary, apex of heart, duodenum, esophagus, gastrocnemius muscle, left testis, lip, mucosa of transverse colon, muscle of thigh, neural tube, prefrontal cortex, right frontal lobe, right hemisphere of cerebellum, right kidney, right testis, Rostral migratory stream, superior frontal gyrus, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
kinase bp gene chr human band protein chromosome 19 mitogen-activated location dual specificity enzyme mouse map mek2 cfc4 mkk2 mapkk2
TTTA extracted 115 structured relationships around MAP2K2. Examples in this analysis include MAP2K2 → 2.7.12.2 → ↗ and MAP2K2 → Aliases → MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2, mitogen-activated protein kinase kinase 2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| MAP2K2 | 2.7.12.2 | ↗ | 1.00 | infobox |
| MAP2K2 | Aliases | MAP2K2, CFC4, MAPKK2, MEK2, MKK2, PRKMK2, mitogen-activated protein kinase kinase 2 | 1.00 | infobox |
| MAP2K2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1S9I, 4H3Q | 1.00 | infobox |
| MAP2K2 | Band | 19p13.3 | 1.00 | infobox |
| MAP2K2 | Band | 10 C1|10 39.72 cM | 1.00 | infobox |
| MAP2K2 | Bgee | mucosa of transverse colon | 1.00 | infobox |
| MAP2K2 | Bgee | right testis | 1.00 | infobox |
| MAP2K2 | Bgee | left testis | 1.00 | infobox |
| MAP2K2 | Bgee | apex of heart | 1.00 | infobox |
| MAP2K2 | Bgee | muscle of thigh | 1.00 | infobox |
| MAP2K2 | Bgee | gastrocnemius muscle | 1.00 | infobox |
| MAP2K2 | Bgee | right frontal lobe | 1.00 | infobox |
| MAP2K2 | Bgee | anterior pituitary | 1.00 | infobox |
| MAP2K2 | Bgee | right hemisphere of cerebellum | 1.00 | infobox |
| MAP2K2 | Bgee | prefrontal cortex | 1.00 | infobox |
| MAP2K2 | Bgee | lip | 1.00 | infobox |
| MAP2K2 | Bgee | right kidney | 1.00 | infobox |
| MAP2K2 | Bgee | yolk sac | 1.00 | infobox |
| MAP2K2 | Bgee | neural tube | 1.00 | infobox |
| MAP2K2 | Bgee | ventricular zone | 1.00 | infobox |
| MAP2K2 | Bgee | duodenum | 1.00 | infobox |
| MAP2K2 | Bgee | esophagus | 1.00 | infobox |
| MAP2K2 | Bgee | superior frontal gyrus | 1.00 | infobox |
| MAP2K2 | Bgee | Rostral migratory stream | 1.00 | infobox |
| MAP2K2 | BioGPS | More reference expression data | 1.00 | infobox |
| MAP2K2 | Chr. | Chromosome 19 (human) | 1.00 | infobox |
| MAP2K2 | Chr. | Chromosome 10 (mouse) | 1.00 | infobox |
| MAP2K2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| MAP2K2 | End | 4,124,122 bp | 1.00 | infobox |
| MAP2K2 | End | 80,969,809 bp | 1.00 | infobox |
The concept neighborhoods around MAP2K2 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Activity. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For MAP2K2, one of the stronger structural bridges in this analysis connects MAP2K2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around MAP2K2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — MAP2K2 · EN edition · Analysis: TopicsToTalkAbout