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Interferon alpha-1

Interferon alpha-1 is a protein that in humans is encoded by the IFNA1 gene.

The type I interferon gene family, Disease relevance & Inducers of type I IFN

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Aliases
IFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@, Interferon, alpha 1, interferon alpha 1, leIF D
Available structures
Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3UX9
Band
9p21.3
Bgee
testicle · cerebellum · primary visual cortex · cerebellar hemisphere · right hemisphere of cerebellum
BioGPS
More reference expression data
Chr.
Chromosome 9 (human)

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Overview

The type I interferon gene family

Type I IFN Signaling

Inducers of type I IFN

Disease relevance

Current and future therapeutic options

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Map overview Semantic statistics

Interferon alpha-1

Nodes92
Edges91
Triples79
Avg. degree1.98
Density0.021739
Components1

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Interferon alpha-1

Top relations

Gene ontology · 20
Interferon alpha-1 → adaptive immune response, B cell differentiation, B cell proliferation, blood coagulation, cytokine activity, cytokine receptor binding, cytokine-mediated signaling pathway, defense response, defense response to virus, extracellular region, extracellular space, humoral immune response, innate immune response, natural killer cell activation involved in immune response, positive regulation of peptidyl-serine phosphorylation of STAT protein, regulation of signaling receptor activity, response to exogenous dsRNA, T cell activation involved in immune response, type I interferon receptor binding, type I interferon signaling pathway
Bgee · 10
Interferon alpha-1 → Brodmann area 9, cerebellar hemisphere, cerebellum, hippocampal formation, hippocampus proper, prefrontal cortex, primary visual cortex, right hemisphere of cerebellum, testicle, urinary bladder
RNA expression pattern · 10
Interferon alpha-1 → Brodmann area 9, cerebellar hemisphere, cerebellum, hippocampal formation, hippocampus proper, prefrontal cortex, primary visual cortex, right hemisphere of cerebellum, testicle, urinary bladder
related to External links · 6
Interferon alpha-1 → Interferon, Overview, P01562, PDB, PDBe-KB, UniProt
Aliases · 1
Interferon alpha-1 → IFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@, Interferon, alpha 1, interferon alpha 1, leIF D
Available structures · 1
Interferon alpha-1 → Available structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3UX9
Band · 1
Interferon alpha-1 → 9p21.3
BioGPS · 1
Interferon alpha-1 → More reference expression data
Chr. · 1
Interferon alpha-1 → Chromosome 9 (human)
Databases · 1
Interferon alpha-1 → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

type ifn interferon gene transcription ifn-α human ifns sle patients ifna pathway genes immune signaling ms ifna1 response bp high

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Interferon alpha-1AliasesIFNA1, IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@, Interferon, alpha 1, interferon alpha 1, leIF D1.00infobox
Interferon alpha-1Available structuresAvailable structuresPDBHuman UniProt search: PDBe RCSB List of PDB id codes3UX91.00infobox
Interferon alpha-1Band9p21.31.00infobox
Interferon alpha-1Bgeetesticle1.00infobox
Interferon alpha-1Bgeecerebellum1.00infobox
Interferon alpha-1Bgeeprimary visual cortex1.00infobox
Interferon alpha-1Bgeecerebellar hemisphere1.00infobox
Interferon alpha-1Bgeeright hemisphere of cerebellum1.00infobox
Interferon alpha-1Bgeehippocampal formation1.00infobox
Interferon alpha-1Bgeeprefrontal cortex1.00infobox
Interferon alpha-1Bgeehippocampus proper1.00infobox
Interferon alpha-1BgeeBrodmann area 91.00infobox
Interferon alpha-1Bgeeurinary bladder1.00infobox
Interferon alpha-1BioGPSMore reference expression data1.00infobox
Interferon alpha-1Chr.Chromosome 9 (human)1.00infobox
Interferon alpha-1DatabasesNCBI: entry; OMA: entry1.00infobox
Interferon alpha-1End21,441,316 bp1.00infobox
Interferon alpha-1EnsemblENSG000001979191.00infobox
Interferon alpha-1Entrez34391.00infobox
Interferon alpha-1External IDsOMIM: 147660; GeneCards: IFNA11.00infobox
Interferon alpha-1Gene location (Human)Gene location (Human)Chr.Chromosome 9 (human)Band9p21.3Start21,440,439 bpEnd21,441,316 bp1.00infobox
Interferon alpha-1Gene ontologycytokine activity1.00infobox
Interferon alpha-1Gene ontologytype I interferon receptor binding1.00infobox
Interferon alpha-1Gene ontologycytokine receptor binding1.00infobox
Interferon alpha-1Gene ontologyextracellular region1.00infobox
Interferon alpha-1Gene ontologyextracellular space1.00infobox
Interferon alpha-1Gene ontologynatural killer cell activation involved in immune response1.00infobox
Interferon alpha-1Gene ontologyB cell differentiation1.00infobox
Interferon alpha-1Gene ontologydefense response1.00infobox
Interferon alpha-1Gene ontologyB cell proliferation1.00infobox

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