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HBx

HBx is a hepatitis B viral protein. It is 154 amino acids long and interferes with transcription, signal transduction, cell cycle progress, protein degradation, apoptosis and chromosomal stability in the host. It forms a heterodimeric complex with its cellular target protein (HBX interacting protein: HBXIP), and this interaction dysregulates centrosome…

Molecular effects of HBx, Overview & Relation to PRMT1

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Molecular effects of HBx

IntracellularReactive oxygen speciesSIRT1HBsAgHBcAg
16 related topics

Overview

Hepatitis BViral proteinAmino acidsCell cycleApoptosis
17 related topics

Relation to PRMT1

ExpressionPRMT1MethyltransferaseMethylation
4 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Domains
InterPro
Organism
Hepatitis B virus genotype B2 (isolate Vietnam/9873/1997)
Orthologs
OMA: entry
Search for
Search forStructuresSwiss-modelDomainsInterPro
Structures
Swiss-model
Symbol
X

Topics to explore

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Overview

Molecular effects of HBx

Relation to PRMT1

Advanced semantic analysis

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Map overview Semantic statistics

HBx

Nodes41
Edges40
Triples25
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

HBx

Top relations

has effect · 9
HBx → DNA, HBcAg, HBsAg, HBV, In, Oxidative DNA, ROS, SIRT1, These
related to Relation to PRMT1 · 7
HBx → HBV, HBV DNA, In, Increased HBx, Overexpression, PRMT1, PRMT1-mediated
Domains · 1
HBx → InterPro
Organism · 1
HBx → Hepatitis B virus genotype B2 (isolate Vietnam/9873/1997)
Orthologs · 1
HBx → OMA: entry
Search for · 1
HBx → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
HBx → Swiss-model
Symbol · 1
HBx → X
UniProt · 1
HBx → P0C685
causes · 1
HBx → dysregulation by binding to genomic DNA

Important terminology Word statistics

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Important terminology

protein transcription dna expression genes hbv hepatitis transgenic also binding virus ros levels cells cgis replication mice cell intracellular prmt1

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
HBxDomainsInterPro1.00infobox
HBxOrganismHepatitis B virus genotype B2 (isolate Vietnam/9873/1997)1.00infobox
HBxOrthologsOMA: entry1.00infobox
HBxSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
HBxStructuresSwiss-model1.00infobox
HBxSymbolX1.00infobox
HBxUniProtP0C6851.00infobox
HBxcausesdysregulation by binding to genomic DNA0.90text
HBxis ahepatitis B viral protein0.90text
HBxhas effectThese0.60section
HBxhas effectROS0.60section
HBxhas effectDNA0.60section

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    Min side: 3
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