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CccDNA

cccDNA (covalently closed circular DNA) is a special DNA structure that arises during the propagation of some viruses in the cell nucleus and may remain permanently there. It is a double-stranded DNA that originates in a linear form that is ligated by means of DNA ligase to a covalently closed ring. In most cases, transcription of viral DNA can occur…

Background of cccDNA and the Hepatitis B virus, Biological functions & Properties of cccDNA

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Overview

Background of cccDNA and the Hepatitis B virus

Properties of cccDNA

Role of cccDNA in HBV replication

Biological functions

Advanced semantic analysis

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Map overview Semantic statistics

CccDNA

Nodes62
Edges61
Triples38
Avg. degree1.97
Density0.032258
Components1

How this topic connects Entity context

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CccDNA

Top relations

related to background · 10
CccDNA → Approximately, Chronic, Closed, Current, DNA, Genomic DNA, HBV, HCC, Hepatitis, The
related to Role of cccDNA in HBV replication · 10
CccDNA → HBsAg, HBV, HepaRG, In, It, Once, PHH, Southern, The, Typically HBV
related to Properties of cccDNA · 9
CccDNA → Although, As, DNA, HBV, HepG2, In, It, RNAs, The
related to Biological functions · 6
CccDNA → After, Deprotonation, DNA, The, This, While
is a · 2
CccDNA → Hepatitis B Virus, reactive intermediate that significantly contributes to infections of hepatocytes

Important terminology Word statistics

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Important terminology

dna hbv virus viral cell infection cells hepatitis hepatocytes infected circular nucleus replication transcription rcdna liver viruses known form covalently

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CccDNAis aHepatitis B Virus0.90text
CccDNAis areactive intermediate that significantly contributes to infections of hepatocytes0.90text
infants can have as high as a 90instance ofhigh-risk individuals0.80text
CccDNArelated to backgroundClosed0.60section
CccDNArelated to backgroundDNA0.60section
CccDNArelated to backgroundGenomic DNA0.60section
CccDNArelated to backgroundHepatitis0.60section
CccDNArelated to backgroundHBV0.60section
CccDNArelated to backgroundApproximately0.60section
CccDNArelated to backgroundHCC0.60section
CccDNArelated to backgroundChronic0.60section
CccDNArelated to backgroundCurrent0.60section

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