Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Amiloride

Amiloride, sold under the trade name Midamor among others, is a medication typically used with other medications to treat high blood pressure or swelling due to heart failure or cirrhosis of the liver. Amiloride is classified as a potassium-sparing diuretic. Amiloride is often used together with another diuretic, such as a thiazide or loop diuretic. It…

History, Community, Culture & Applications

Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.

Research this topic

Explore the main themes, entities and connections around Amiloride. Start with the topic map, then use the sections below for research and deeper semantic analysis.

Explore this topic

Start with a few of the strongest sections from the source topic. These are research directions, not a list of keywords you must use.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
C03DB01 (WHO)
Bioavailability
Readily absorbed, 15–25%
CAS Number
2016-88-8 Y
ChEBI
CHEBI:2639 Y

Topics to explore

Browse the full topic structure. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Contraindications

Adverse effects

Interactions

Pharmacology

Chemistry

History

Society and culture

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Amiloride

Nodes119
Edges118
Triples106
Avg. degree1.98
Density0.016807
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Amiloride

Top relations

related to Research · 17
Amiloride → Aerosolized, Cancer, CFTR, Cystic, DMA, Due, EIPA, ENaC, HMA, However, Modified, N'-4, N-dimethyl, N-ethyl-N-isopropyl, N-hexamethylene, NHE-1, There
related to Medical uses · 15
Amiloride → ACE-i, American College, ARB, Because Liddle, Cardiology/American Heart Association Task, Clinical Practice Guidelines, Digitalis, ENaC, For, Force, II, Liddle, Some, The, When
related to External links · 8
Amiloride → Archived, Drug Information Portal, January, Media, Medicine, National Library, Wikimedia Commons, Wiktionary-logo-en-v2
related to history · 8
Amiloride → Dohme Research Laboratories, Drug Administration, FDA, Food, Merck Sharp, October, The, Thousands
related to Society and culture · 7
Amiloride → Diuretics, Essential Medicines, In, It, The, World Anti-Doping Agency's, World Health Organization's List
related to Interactions · 4
Amiloride → ACE, AT1, For, II
Legal status · 3
Amiloride → AU: S4 (Prescription only), UK: POM (Prescription only), US: ℞-only
related to Overdose · 3
Amiloride → It, There, Treatment
has effect · 2
Amiloride → Common, Mild
related to Chemistry · 2
Amiloride → Amiloride's, In

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

potassium blood effects high sodium due enac kidney people used hyperkalemia risk diuretic drug potassium-sparing action excretion may channel thiazide

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Amiloride3D model (JSmol)Interactive image1.00infobox
AmilorideAHFS/Drugs.comMonograph1.00infobox
AmilorideATC codeC03DB01 (WHO)1.00infobox
AmilorideBioavailabilityReadily absorbed, 15–25%1.00infobox
AmilorideCAS Number2016-88-8 Y1.00infobox
AmilorideChEBICHEBI:2639 Y1.00infobox
AmilorideChEMBLChEMBL945 Y1.00infobox
AmilorideChemSpider15403 Y1.00infobox
AmilorideCompTox Dashboard (EPA)DTXSID90438531.00infobox
AmilorideDrugBankDB00594 Y1.00infobox
AmilorideECHA InfoCard100.018.2051.00infobox
AmilorideElimination half-life6 to 9 hours1.00infobox
AmilorideExcretionurine (20–50%), feces (40%)1.00infobox
AmilorideFormulaC6H8ClN7O1.00infobox
AmilorideIUPHAR/BPS24211.00infobox
AmilorideKEGGD07447 Y1.00infobox
AmilorideLegal statusAU: S4 (Prescription only)1.00infobox
AmilorideLegal statusUK: POM (Prescription only)1.00infobox
AmilorideLegal statusUS: ℞-only1.00infobox
AmilorideMelting point240.5 to 241.5 °C (464.9 to 466.7 °F)1.00infobox
AmilorideMetabolismNil1.00infobox
AmilorideMolar mass229.63 g·mol−11.00infobox
AmilorideOnset of action2 hours (peak at 6–10 hours, duration ~24 hours)1.00infobox
AmilorideOther namesMK-8701.00infobox
AmiloridePregnancy categoryAU: C1.00infobox
AmilorideProtein binding~23%1.00infobox
AmiloridePubChem CID162311.00infobox
AmilorideRoutes of administrationBy mouth1.00infobox
AmilorideTrade namesMidamor, others1.00infobox
AmilorideUNII7M458Q65S31.00infobox

Related concept clusters Concept neighborhoods

These clusters group vocabulary that occurs around closely connected concepts in the source material.

    Connections between topic areas Semantic bridges

    Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.

    Min side: 3
    For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.