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Polymyxins are antibiotics. Polymyxins B and E (also known as colistin) are used in the treatment of Gram-negative bacterial infections. They work mostly by breaking up the bacterial cell membrane. They are part of a broader class of molecules called nonribosomal peptides.
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polymyxins bacterial also used membrane bacteria lps acid gram-positive paenibacillus antibiotics resistance residues chain b1 gram-negative infections cell polymyxa drug
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Paenibacillus polymyxa | instance of | They are part of a broader class of molecules called nonribosomal peptides.They are produced in nature by Gram-positive bacteria | 0.80 | text |
| P. polymyxa PKB1 have been observed to incorporate DAB with the D | instance of | however certain strains | 0.80 | text |
| Paenibacillus polymyxa | instance of | BiosynthesisThe polymyxins are produced by nonribosomal peptide synthetase systems in Gram-positive bacteria | 0.80 | text |
| Polymyxin | related to Biosynthesis | The | 0.60 | section |
| Polymyxin | related to Biosynthesis | Gram-positive | 0.60 | section |
| Polymyxin | related to Biosynthesis | Paenibacillus | 0.60 | section |
| Polymyxin | related to Biosynthesis | Like | 0.60 | section |
| Polymyxin | related to Biosynthesis | NRPs | 0.60 | section |
| Polymyxin | related to Biosynthesis | C-terminal | 0.60 | section |
| Polymyxin | related to Chemistry | Polymyxins | 0.60 | section |
| Polymyxin | related to Chemistry | NRPs | 0.60 | section |
| Polymyxin | related to Chemistry | Paenibacillus | 0.60 | section |
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