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Epigenomics

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell. Epigenetic modifications are reversible modifications on a cell's DNA or histones that affect gene expression…

Regions, Epigenetics & Methods

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Overview

Epigenetics

Relation to other genomic fields

Methods

Theoretical modeling approaches

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Map overview Semantic statistics

Epigenomics

Nodes103
Edges102
Triples20
Avg. degree1.98
Density0.019417
Components1

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Epigenomics

Top relations

related to Relation to other genomic fields · 5
Epigenomics → As, DNA, However, Many, The
see also · 3
Epigenomics → Biology, EpigeneticsEpigenetic, Epigenome ProjectEpigenomics AGSingle
is a · 1
Epigenomics → study of the complete set of epigenetic modifications on the genetic material of a cell

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Important terminology

dna methylation chromatin histone epigenetic modifications sequencing gene modification expression regions genome polymerase restriction used methods sites possible genomic assays

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Epigenomicsis astudy of the complete set of epigenetic modifications on the genetic material of a cell0.90text
in differentiation/developmentinstance ofand are involved in numerous cellular processes0.80text
tumorigenesisinstance ofand are involved in numerous cellular processes0.80text
humans is limited.In order to study histone modifications on a truly genome levelinstance ofits use in larger genomes0.80text
other high-throughput methods were coupled with the chromatin immunoprecipitationinstance ofits use in larger genomes0.80text
namelyinstance ofits use in larger genomes0.80text
MNase-seqinstance ofAssays0.80text
DNase-seqinstance ofAssays0.80text
ATAC-seqinstance ofAssays0.80text
or FAIRE-seq are routinely used to understand the accessible chromatin landscape of cellsinstance ofAssays0.80text
methylation as the polymerase moves along the DNA molecule being sequencedinstance ofand have been used to map chromatin accessibility and histone marks in human dorsal root ganglion and other mammalian tissues.Direct detectionPolymerase sensitivity in single-mo…0.80text
methylation as the polymerase moves along the DNA molecule being sequencedinstance ofDirect detectionPolymerase sensitivity in single-molecule real-time sequencing made it possible for scientists to directly detect epigenetic marks0.80text

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