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ARHGAP1: Interactions & Overview

Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the ARHGAP1 gene.

Language: English [EN]
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ARHGAP1 topic overview

The analysis highlights Interactions and Overview as prominent areas in the source structure around ARHGAP1.

Related topics
6
Source areas
2
Connected nodes
8
Extracted relationships
86
Concept neighborhoods
5
Bridge connections
8

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ARHGAP1, CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP, Rho GTPase activating protein 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AM4, 1GRN, 1OW3, 1RGP, 1TX4, 2NGR
Band
11p11.2 · 2|2 E1
Bgee
gingival epithelium · saphenous vein · epithelium of esophagus · parietal pleura · visceral pleura
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How ARHGAP1 connects Entity context

The extracted context around ARHGAP1 shows recurring relationship patterns in the source. For example, ARHGAP1 → cadherin binding, cytoplasm, cytosol, endosomal transport, endosome membrane, extracellular exosome, GTPase activator activity, integral component of membrane, iron ion import across cell outer membrane, membrane, negative regulation of endocytic recycling, perinuclear region of cytoplasm, positive regulation of GTPase activity, positive regulation of signal transduction, protein binding, regulation of small GTPase mediated signal transduction, Rho protein signal transduction, SH3 domain binding, signal transduction, small GTPase mediated signal transduction Another extracted example is ARHGAP1 → amniotic fluid, blastocyst, corneal stroma, decidua, dentate gyrus of hippocampal formation granule cell, epithelium of esophagus, genital tubercle, gingival epithelium, granulocyte, lip, morula, parietal pleura, saphenous vein, tail of embryo, tail of epididymis, urethra, vena cava, visceral pleura, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

ARHGAP1

Top relations

Gene ontology · 22
ARHGAP1 → cadherin binding, cytoplasm, cytosol, endosomal transport, endosome membrane, extracellular exosome, GTPase activator activity, integral component of membrane, iron ion import across cell outer membrane, membrane, negative regulation of endocytic recycling, perinuclear region of cytoplasm, positive regulation of GTPase activity, positive regulation of signal transduction, protein binding, regulation of small GTPase mediated signal transduction, Rho protein signal transduction, SH3 domain binding, signal transduction, small GTPase mediated signal transduction
Bgee · 19
ARHGAP1 → amniotic fluid, blastocyst, corneal stroma, decidua, dentate gyrus of hippocampal formation granule cell, epithelium of esophagus, genital tubercle, gingival epithelium, granulocyte, lip, morula, parietal pleura, saphenous vein, tail of embryo, tail of epididymis, urethra, vena cava, visceral pleura, yolk sac
RNA expression pattern · 19
ARHGAP1 → amniotic fluid, blastocyst, corneal stroma, decidua, dentate gyrus of hippocampal formation granule cell, epithelium of esophagus, genital tubercle, gingival epithelium, granulocyte, lip, morula, parietal pleura, saphenous vein, tail of embryo, tail of epididymis, urethra, vena cava, visceral pleura, yolk sac
Band · 2
ARHGAP1 → 11p11.2, 2|2 E1
Chr. · 2
ARHGAP1 → Chromosome 11 (human), Chromosome 2 (mouse)
End · 2
ARHGAP1 → 46,700,619 bp, 91,502,671 bp
related to External links · 2
ARHGAP1 → Human ARHGAP1, UCSC Genome Browser
Aliases · 1
ARHGAP1 → ARHGAP1, CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP, Rho GTPase activating protein 1
Available structures · 1
ARHGAP1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AM4, 1GRN, 1OW3, 1RGP, 1TX4, 2NGR
BioGPS · 1
ARHGAP1 → More reference expression data

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp human gene chr band chromosome 11 location rho protein mouse external gtpase search 700 619 end 46 502 671

ARHGAP1 relationships Subject–Predicate–Object triples

TTTA extracted 86 structured relationships around ARHGAP1. Examples in this analysis include ARHGAP1 → Aliases → ARHGAP1, CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP, Rho GTPase activating protein 1 and ARHGAP1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AM4, 1GRN, 1OW3, 1RGP, 1TX4, 2NGR. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
ARHGAP1AliasesARHGAP1, CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP, Rho GTPase activating protein 11.00infobox
ARHGAP1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1AM4, 1GRN, 1OW3, 1RGP, 1TX4, 2NGR1.00infobox
ARHGAP1Band11p11.21.00infobox
ARHGAP1Band2|2 E11.00infobox
ARHGAP1Bgeegingival epithelium1.00infobox
ARHGAP1Bgeesaphenous vein1.00infobox
ARHGAP1Bgeeepithelium of esophagus1.00infobox
ARHGAP1Bgeeparietal pleura1.00infobox
ARHGAP1Bgeevisceral pleura1.00infobox
ARHGAP1Bgeeamniotic fluid1.00infobox
ARHGAP1Bgeeurethra1.00infobox
ARHGAP1Bgeedecidua1.00infobox
ARHGAP1Bgeetail of epididymis1.00infobox
ARHGAP1Bgeevena cava1.00infobox
ARHGAP1Bgeeyolk sac1.00infobox
ARHGAP1Bgeegranulocyte1.00infobox
ARHGAP1Bgeecorneal stroma1.00infobox
ARHGAP1Bgeelip1.00infobox
ARHGAP1Bgeegenital tubercle1.00infobox
ARHGAP1Bgeetail of embryo1.00infobox
ARHGAP1Bgeemorula1.00infobox
ARHGAP1Bgeeblastocyst1.00infobox
ARHGAP1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
ARHGAP1BioGPSMore reference expression data1.00infobox
ARHGAP1Chr.Chromosome 11 (human)1.00infobox
ARHGAP1Chr.Chromosome 2 (mouse)1.00infobox
ARHGAP1DatabasesNCBI: entry; OMA: entry1.00infobox
ARHGAP1End46,700,619 bp1.00infobox
ARHGAP1End91,502,671 bp1.00infobox
ARHGAP1EnsemblENSG000001752201.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around ARHGAP1 bring nearby vocabulary together. In this analysis, examples include Gene, Protein and Rho. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • ARHGAP1
    • Gene
    • Protein
    • Rho
    • Location
    • Gtpase
    • Human
    • Search
    • Ucsc
    • Chromosome
    • Bp
    • Chr
    • Encoded
  • arhgap1
    • Gene
    • Protein
    • Rho
    • Location
    • Gtpase
    • Human
    • Search
    • Ucsc
    • Chromosome
    • Bp
    • Chr
    • Encoded
  • gene
    • Location
    • Human
    • Protein
    • Rho
    • Chromosome
    • Bp
    • Chr
    • End
    • Gtpase
    • Mouse
    • Search
    • Ucsc
  • interactions
    • External
    • Links
    • Reading
    • References
    • Gtpase
    • Search
    • Protein
    • Rho
    • Chromosome
    • Location
    • Bp
    • Chr
  • enzyme
    • Encoded
    • Gtpase-activating
    • Humans
    • Protein
    • Rho
    • Arhgap1
    • Gene

Connections between topic areas Semantic bridges

For ARHGAP1, one of the stronger structural bridges in this analysis connects ARHGAP1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
ARHGAP1Interactions · splits 4 ⟂ 5
ARHGAP1Overview · splits 6 ⟂ 3

Map overview Semantic statistics

ARHGAP1

Nodes9
Edges8
Triples86
Avg. degree1.78
Density0.222222
Components1

Source & methodology

TTTA analyzes the structure around ARHGAP1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Interactions & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — ARHGAP1 · EN edition · Analysis: TopicsToTalkAbout

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