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CD70: Expression, Functions & Drug development

CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. CD70 is also known as a ligand for CD27.

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CD70 topic overview

The analysis highlights Expression, Functions and Drug development as prominent areas in the source structure around CD70.

Related topics
34
Source areas
4
Connected nodes
38
Extracted relationships
64
Concept neighborhoods
15
Bridge connections
38

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Expression · 14 topics
Functions · 10 topics
Drug development · 8 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
CD27LG, TNFSF7
Domains
InterPro
HGNC
11937
Locus
Chr. 19 p13
NCBI gene
970
OMIM
602840

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Expression

Functions

Drug development

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CD70 connects Entity context

The extracted context around CD70 shows recurring relationship patterns in the source. For example, CD70 → Also, CD40, Expression, GM-CSF, IL-10, IL-12, IL-15, IL-1α, IL-2, IL-4, In, It, NK, TLR, TNF-α, Toll-like Another extracted example is CD70 → APC, B-cell, CD27, CD4, JNK, NF-κB, T-bet, T-cell, Th1, The, TRAF2, TRAF5. Use these groups to spot repeated connection types before inspecting the individual relationships.

CD70

Top relations

related to Expression · 16
CD70 → Also, CD40, Expression, GM-CSF, IL-10, IL-12, IL-15, IL-1α, IL-2, IL-4, In, It, NK, TLR, TNF-α, Toll-like
related to Functions · 12
CD70 → APC, B-cell, CD27, CD4, JNK, NF-κB, T-bet, T-cell, Th1, The, TRAF2, TRAF5
related to Drug development · 10
CD70 → ARGX-110, Belgian, CD70-specific, CD70-targeted, In December, In January, It, One, Recent, Vorsetuzumab
related to Cancer · 4
CD70 → Hodgkin's, It, Some, This
related to External links · 4
CD70 → Antigens, Medicine Medical Subject Headings, MeSH, National Library
Alt. symbols · 1
CD70 → CD27LG, TNFSF7
Domains · 1
CD70 → InterPro
HGNC · 1
CD70 → 11937
Locus · 1
CD70 → Chr. 19 p13
NCBI gene · 1
CD70 → 970

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

also cells expression cd27 cancer cell activation signaling differentiation p13 gene proliferation survival leading including lymphocytes treatment cluster chr 19

CD70 relationships Subject–Predicate–Object triples

TTTA extracted 64 structured relationships around CD70. Examples in this analysis include CD70 → Alt. symbols → CD27LG, TNFSF7 and CD70 → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CD70Alt. symbolsCD27LG, TNFSF71.00infobox
CD70DomainsInterPro1.00infobox
CD70HGNC119371.00infobox
CD70LocusChr. 19 p131.00infobox
CD70NCBI gene9701.00infobox
CD70OMIM6028401.00infobox
CD70RefSeqNM_0012521.00infobox
CD70Search forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
CD70StructuresSwiss-model1.00infobox
CD70SymbolCD701.00infobox
CD70UniProtP329701.00infobox
IL-1αinstance ofCD70 expression on T and B cells is stimulated through triggering of T and B cell receptors and can be upregulated by cytokines0.80text

Related concept clusters Concept neighborhoods

The concept neighborhoods around CD70 bring nearby vocabulary together. In this analysis, examples include Also, Expression and Cells. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CD70
    • Also
    • Expression
    • Cells
    • Cancer
    • Differentiation
    • Including
    • Leading
    • Proliferation
    • Survival
    • Activation
    • Cd27
    • Cell
  • cd70
    • Also
    • Expression
    • Cells
    • Cancer
    • Differentiation
    • Including
    • Leading
    • Proliferation
    • Survival
    • Activation
    • Cd27
    • Cell
  • nk cells
    • Activated
    • Dendritic
    • Induced
    • Cells
    • Nk
    • Lymphocytes
    • Cell
    • Expression
    • Also
    • Costimulatory
    • Development
    • Immune
  • t cells
    • Activated
    • Dendritic
    • Nk
    • Lymphocytes
    • Cell
    • Expression
    • Costimulatory
    • Development
    • Immune
    • Induced
    • P13
    • Transcription
  • b cells
    • Activated
    • Dendritic
    • Nk
    • Lymphocytes
    • Cell
    • Expression
    • Costimulatory
    • Development
    • Immune
    • Induced
    • P13
    • Transcription
  • dendritic cells
    • Costimulatory
    • Nk
    • Activated
    • Dendritic
    • Including
    • Lymphocytes
    • Cell
    • Expression
    • Development
    • Immune
    • Induced
    • P13
  • antigen presenting cells
    • Activated
    • Dendritic
    • Nk
    • Lymphocytes
    • Cell
    • Expression
    • Costimulatory
    • Development
    • Immune
    • Induced
    • P13
    • Transcription
  • th1 cells
    • Activated
    • Dendritic
    • Nk
    • Lymphocytes
    • Cell
    • Expression
    • Costimulatory
    • Development
    • Immune
    • Induced
    • P13
    • Transcription

Connections between topic areas Semantic bridges

For CD70, one of the stronger structural bridges in this analysis connects CD70 with Expression. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CD70Expression · splits 24 ⟂ 15
CD70Functions · splits 28 ⟂ 11
CD70Drug development · splits 30 ⟂ 9
CD70Overview · splits 36 ⟂ 3

Map overview Semantic statistics

CD70

Nodes39
Edges38
Triples64
Avg. degree1.95
Density0.051282
Components1

Source & methodology

TTTA analyzes the structure around CD70 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Expression, Functions & Drug development, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CD70 · EN edition · Analysis: TopicsToTalkAbout

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