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YTHDC1: Art, Interactions & Role in disease

YTH domain-containing protein 1 is a protein that in humans is encoded by the YTHDC1 gene. YTHDC1 is a nuclear protein involved in splice site selection that localises to YT bodies; dynamic subnuclear compartments, which first appear at the beginning of S-phase in the cell cycle and disperse during mitosis.

Language: English [EN]
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YTHDC1 topic overview

The analysis highlights Art, Interactions and Role in disease as prominent areas in the source structure around YTHDC1.

Related topics
12
Source areas
3
Connected nodes
15
Extracted relationships
90
Concept neighborhoods
8
Bridge connections
15

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 6 topics
Role in disease · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
YTHDC1, YT521, YT521-B, YTH domain containing 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUD, 4R3H, 4R3I
Band
4q13.2 · 5|5 E1
Bgee
Achilles tendon · corpus callosum · sural nerve · left ovary · bone marrow
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 5 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Interactions

Role in disease

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How YTHDC1 connects Entity context

The extracted context around YTHDC1 shows recurring relationship patterns in the source. For example, YTHDC1 → Achilles tendon, bone marrow, ciliary body, conjunctival fornix, corpus callosum, cumulus cell, endometrium, left ovary, medullary collecting duct, Paneth cell, pineal gland, renal corpuscle, right lung, right ovary, Rostral migratory stream, sural nerve, ureter, vagina, ventricular zone, vestibular membrane of cochlear duct Another extracted example is YTHDC1 → dosage compensation by inactivation of X chromosome, mRNA export from nucleus, mRNA processing, mRNA splice site selection, N6-methyladenosine-containing RNA binding, nuclear speck, nucleoplasm, nucleus, plasma membrane, posttranscriptional regulation of gene expression, protein binding, regulation of mRNA splicing, via spliceosome, RNA binding, RNA splicing. Use these groups to spot repeated connection types before inspecting the individual relationships.

YTHDC1

Top relations

Bgee · 20
YTHDC1 → Achilles tendon, bone marrow, ciliary body, conjunctival fornix, corpus callosum, cumulus cell, endometrium, left ovary, medullary collecting duct, Paneth cell, pineal gland, renal corpuscle, right lung, right ovary, Rostral migratory stream, sural nerve, ureter, vagina, ventricular zone, vestibular membrane of cochlear duct
RNA expression pattern · 20
YTHDC1 → Achilles tendon, bone marrow, ciliary body, conjunctival fornix, corpus callosum, cumulus cell, endometrium, left ovary, medullary collecting duct, Paneth cell, pineal gland, renal corpuscle, right lung, right ovary, Rostral migratory stream, sural nerve, ureter, vagina, ventricular zone, vestibular membrane of cochlear duct
Gene ontology · 14
YTHDC1 → dosage compensation by inactivation of X chromosome, mRNA export from nucleus, mRNA processing, mRNA splice site selection, N6-methyladenosine-containing RNA binding, nuclear speck, nucleoplasm, nucleus, plasma membrane, posttranscriptional regulation of gene expression, protein binding, regulation of mRNA splicing, via spliceosome, RNA binding, RNA splicing
related to Cancer · 7
YTHDC1 → BRCA1, CD44, DNA, In, MTDH, PGR, VEGF
related to Interactions · 4
YTHDC1 → Abl, C-src, Emerin, KHDRBS1
Band · 2
YTHDC1 → 4q13.2, 5|5 E1
Chr. · 2
YTHDC1 → Chromosome 4 (human), Chromosome 5 (mouse)
End · 2
YTHDC1 → 68,350,090 bp, 86,984,518 bp
Aliases · 1
YTHDC1 → YTHDC1, YT521, YT521-B, YTH domain containing 1
Available structures · 1
YTHDC1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUD, 4R3H, 4R3I

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp gene chr human band protein chromosome cancer splice location mouse splicing yth nuclear site selection cell shown encoded search

YTHDC1 relationships Subject–Predicate–Object triples

TTTA extracted 90 structured relationships around YTHDC1. Examples in this analysis include YTHDC1 → Aliases → YTHDC1, YT521, YT521-B, YTH domain containing 1 and YTHDC1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUD, 4R3H, 4R3I. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
YTHDC1AliasesYTHDC1, YT521, YT521-B, YTH domain containing 11.00infobox
YTHDC1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2YUD, 4R3H, 4R3I1.00infobox
YTHDC1Band4q13.21.00infobox
YTHDC1Band5|5 E11.00infobox
YTHDC1BgeeAchilles tendon1.00infobox
YTHDC1Bgeecorpus callosum1.00infobox
YTHDC1Bgeesural nerve1.00infobox
YTHDC1Bgeeleft ovary1.00infobox
YTHDC1Bgeebone marrow1.00infobox
YTHDC1Bgeeendometrium1.00infobox
YTHDC1Bgeeventricular zone1.00infobox
YTHDC1Bgeeright ovary1.00infobox
YTHDC1Bgeeright lung1.00infobox
YTHDC1Bgeevagina1.00infobox
YTHDC1Bgeemedullary collecting duct1.00infobox
YTHDC1Bgeeconjunctival fornix1.00infobox
YTHDC1Bgeerenal corpuscle1.00infobox
YTHDC1Bgeecumulus cell1.00infobox
YTHDC1Bgeeureter1.00infobox
YTHDC1Bgeeciliary body1.00infobox
YTHDC1Bgeepineal gland1.00infobox
YTHDC1Bgeevestibular membrane of cochlear duct1.00infobox
YTHDC1BgeeRostral migratory stream1.00infobox
YTHDC1BgeePaneth cell1.00infobox
YTHDC1BioGPSMore reference expression data1.00infobox
YTHDC1Chr.Chromosome 4 (human)1.00infobox
YTHDC1Chr.Chromosome 5 (mouse)1.00infobox
YTHDC1DatabasesNCBI: entry; OMA: entry1.00infobox
YTHDC1End68,350,090 bp1.00infobox
YTHDC1End86,984,518 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around YTHDC1 bring nearby vocabulary together. In this analysis, examples include Cancer, Protein and Shown. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • YTHDC1
    • Cancer
    • Protein
    • Shown
    • Splice
    • Gene
    • Also
    • Alternative
    • Cell
    • Encoded
    • Interact
    • Metadherin
    • Mrna
  • ythdc1
    • Cancer
    • Protein
    • Shown
    • Splice
    • Gene
    • Also
    • Alternative
    • Cell
    • Encoded
    • Interact
    • Metadherin
    • Mrna
  • protein
    • Ythdc1
    • Alternative
    • Cell
    • Encoded
    • Interact
    • Metadherin
    • Nuclear
    • Selection
    • Site
    • Splicing
    • Shown
    • Splice
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Mouse
    • Search
    • Yth
    • Ythdc1
    • Band
    • Cancer
  • abl gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • End
    • Mouse
    • Search
    • Yth
    • Ythdc1
    • Band
    • Cancer
  • breast cancer 1 (brca1)
    • Shown
    • Ythdc1
    • Alternative
    • Interact
    • Metadherin
    • Mrna
    • Search
    • Splicing
    • Location
    • Splice
    • Chromosome
    • Gene
  • interact
    • Metadherin
    • Splicing
    • Shown
    • Protein
    • Mouse
    • Mrna
    • Nuclear
    • Search
    • Selection
    • Site
    • Ythdc1
    • Location
  • metadherin
    • Splicing
    • Shown
    • Protein
    • Mouse
    • Mrna
    • Nuclear
    • Search
    • Selection
    • Site
    • Ythdc1
    • Splice

Connections between topic areas Semantic bridges

For YTHDC1, one of the stronger structural bridges in this analysis connects YTHDC1 with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
YTHDC1Interactions · splits 9 ⟂ 7
YTHDC1Role in disease · splits 11 ⟂ 5
YTHDC1Overview · splits 13 ⟂ 3

Map overview Semantic statistics

YTHDC1

Nodes16
Edges15
Triples90
Avg. degree1.88
Density0.125
Components1

Source & methodology

TTTA analyzes the structure around YTHDC1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Interactions & Role in disease, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — YTHDC1 · EN edition · Analysis: TopicsToTalkAbout

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