L-selectin

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L-selectin topic overview

The analysis highlights Ligands, Clinical significance and Expression as prominent areas in the source structure around L-selectin.

Related topics: 32
Source areas: 5
Connected nodes: 37
Extracted relationships: 126
Concept neighborhoods: 18
Bridge connections: 37

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Ligands · 8 topics

Overview · 8 topics

Clinical significance · 7 topics

Expression · 5 topics

Function · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LGF, 3CFW
Band: 1q24.2 · 1 H2.2|1 71.37 cM
Bgee: blood · monocyte · granulocyte · bone marrow · appendix
BioGPS: More reference expression data
Chr.: Chromosome 1 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How L-selectin connects Entity context

The extracted context around L-selectin shows recurring relationship patterns in the source. For example, L-selectin → calcium ion binding, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, carbohydrate binding, cell adhesion, cell adhesion molecule binding, cell surface, external side of plasma membrane, glycosphingolipid binding, heparin binding, integral component of membrane, integral component of plasma membrane, leukocyte migration, leukocyte tethering or rolling, membrane, metal ion binding, neutrophil degranulation, oligosaccharide binding, plasma membrane, protease binding, protein binding Another extracted example is L-selectin → appendix, blood, bone marrow, bone marrow cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, periodontal fiber, right lung, right lung lobe, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, trabecular bone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 23

L-selectin → calcium ion binding, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, carbohydrate binding, cell adhesion, cell adhesion molecule binding, cell surface, external side of plasma membrane, glycosphingolipid binding, heparin binding, integral component of membrane, integral component of plasma membrane, leukocyte migration, leukocyte tethering or rolling, membrane, metal ion binding, neutrophil degranulation, oligosaccharide binding, plasma membrane, protease binding, protein binding

Bgee · 16

L-selectin → appendix, blood, bone marrow, bone marrow cell, granulocyte, lymph node, mesenteric lymph nodes, monocyte, periodontal fiber, right lung, right lung lobe, spleen, subcutaneous adipose tissue, thymus, tibiofemoral joint, trabecular bone

RNA expression pattern · 16

related to External links · 12

L-selectin → Immunology, MCG1/physrespOverview, Medicine, Medicine Medical Subject Headings, MeSH, National Library, P14151, PDB, PDBe-KB, This, UniProt, United States National Library

related to Lymphocytes · 8

L-selectin → Central, Effector, Here, High, Ligands, Naive T-lymphocytes, T-lymphocytes, The

related to Expression · 7

L-selectin → ADAM17, E-selectin, Ectodomain, FOXO, Human, Over, The

related to Neutrophils and monocytes · 6

L-selectin → Adhesion, AMC, MAPK, Prolonged, Similar, The

related to Human immunodeficiency virus (HIV) · 5

L-selectin → CD4, HIV, Infection, The, This

related to Embryo · 4

L-selectin → MUC-1, Removal, Similar, The

Band · 2

L-selectin → 1 H2.2|1 71.37 cM, 1q24.2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cells human adhesion neutrophils cell expression ligands expressed monocytes lymphoid lymphocytes shedding also bp embryo gene found sell binding chr

L-selectin relationships Subject–Predicate–Object triples

TTTA extracted 126 structured relationships around L-selectin. Examples in this analysis include L-selectin → Aliases → SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L and L-selectin → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LGF, 3CFW. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
L-selectin	Aliases	SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L	1.00	infobox
L-selectin	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2LGF, 3CFW	1.00	infobox
L-selectin	Band	1q24.2	1.00	infobox
L-selectin	Band	1 H2.2\|1 71.37 cM	1.00	infobox
L-selectin	Bgee	blood	1.00	infobox
L-selectin	Bgee	monocyte	1.00	infobox
L-selectin	Bgee	granulocyte	1.00	infobox
L-selectin	Bgee	bone marrow	1.00	infobox
L-selectin	Bgee	appendix	1.00	infobox
L-selectin	Bgee	bone marrow cell	1.00	infobox
L-selectin	Bgee	spleen	1.00	infobox
L-selectin	Bgee	trabecular bone	1.00	infobox
L-selectin	Bgee	lymph node	1.00	infobox
L-selectin	Bgee	periodontal fiber	1.00	infobox
L-selectin	Bgee	mesenteric lymph nodes	1.00	infobox
L-selectin	Bgee	tibiofemoral joint	1.00	infobox
L-selectin	Bgee	thymus	1.00	infobox
L-selectin	Bgee	subcutaneous adipose tissue	1.00	infobox
L-selectin	Bgee	right lung	1.00	infobox
L-selectin	Bgee	right lung lobe	1.00	infobox
L-selectin	BioGPS	More reference expression data	1.00	infobox
L-selectin	Chr.	Chromosome 1 (human)	1.00	infobox
L-selectin	Chr.	Chromosome 1 (mouse)	1.00	infobox
L-selectin	Databases	NCBI: entry; OMA: entry	1.00	infobox
L-selectin	End	169,711,702 bp	1.00	infobox
L-selectin	End	163,911,750 bp	1.00	infobox
L-selectin	Ensembl	ENSG00000188404	1.00	infobox
L-selectin	Entrez	6402	1.00	infobox
L-selectin	External IDs	OMIM: 153240; MGI: 98279; GeneCards: SELL	1.00	infobox
L-selectin	Gene location (Human)	Gene location (Human)Chr.Chromosome 1 (human)Band1q24.2Start169,690,665 bpEnd169,711,702 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around L-selectin bring nearby vocabulary together. In this analysis, examples include Cells, Expression and Expressed. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

L-selectin
- Cells
- Expression
- Expressed
- Shedding
- Ligands
- Neutrophils
- Role
- Binding
- Lymphocytes
- Lymphoid
- Human
- Express
l-selectin
- Cells
- Expression
- Expressed
- Shedding
- Ligands
- Neutrophils
- Role
- Binding
- Lymphocytes
- Lymphoid
- Human
- Express
cell adhesion molecule
- Binding
- Surface
- Adhesion
- Cell
- Receptor
- Rolling
- L-selectin
- Immune
- Expressed
- Ligands
- Lymphocytes
- Shedding
hematopoietic stem cells
- Expressed
- Lymphoid
- L-selectin
- Endothelial
- Found
- Monocytes
- Immune
- Tissue
- Lymph
- Migration
- Role
- Rolling
gut-associated lymphoid tissue
- Secondary
- Immune
- Endothelial
- Cells
- Lymphoid
- Tissue
- High
- Location
- Monocytes
- Band
- Expressed
- Function
t cells
- Expressed
- Lymphoid
- L-selectin
- Endothelial
- Found
- Monocytes
- Immune
- Tissue
- Lymph
- Migration
- Role
- Rolling
b cells
- Expressed
- Lymphoid
- L-selectin
- Endothelial
- Found
- Monocytes
- Immune
- Tissue
- Lymph
- Migration
- Role
- Rolling
monocytes
- Lymphocytes
- Neutrophils
- Shedding
- Migration
- Role
- Secondary
- Lymphoid
- Cells
- Location
- Function
- Hiv
- Tissue

Connections between topic areas Semantic bridges

For L-selectin, one of the stronger structural bridges in this analysis connects L-selectin with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

L-selectin — Overview · splits 29 ⟂ 9

L-selectin — Ligands · splits 29 ⟂ 9

L-selectin — Clinical significance · splits 30 ⟂ 8

L-selectin — Expression · splits 32 ⟂ 6

L-selectin — Function · splits 33 ⟂ 5

Map overview Semantic statistics

L-selectin

Nodes38

Edges37

Triples126

Avg. degree1.95

Density0.052632

Components1

Source & methodology

TTTA analyzes the structure around L-selectin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Ligands, Clinical significance & Expression, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — L-selectin · EN edition · Analysis: TopicsToTalkAbout