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HLA class II histocompatibility antigen gamma chain also known as HLA-DR antigens-associated invariant chain or CD74 (Cluster of Differentiation 74), is a protein that in humans is encoded by the CD74 gene. The invariant chain (Abbreviated Ii) is a polypeptide which plays a critical role in antigen presentation. It is involved in the formation and…
History, Clinical significance & Function
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ii mhc class chain invariant cell human antigen bp gene surface chr band clip receptor chromosome protein also presentation peptide
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| CD74 | Aliases | CD74, DHLAG, HLADG, II, Ia-GAMMA, CD74 molecule, p33, CLIP | 1.00 | infobox |
| CD74 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1A6A, 1ICF, 1IIE, 1L3H, 1MUJ, 3PDO, 3PGC, 3PGD, 3QXA, 3QXD, 4AEN, 4X5W | 1.00 | infobox |
| CD74 | Band | 5q33.1 | 1.00 | infobox |
| CD74 | Band | 18 E1|18 34.41 cM | 1.00 | infobox |
| CD74 | Bgee | monocyte | 1.00 | infobox |
| CD74 | Bgee | appendix | 1.00 | infobox |
| CD74 | Bgee | granulocyte | 1.00 | infobox |
| CD74 | Bgee | spleen | 1.00 | infobox |
| CD74 | Bgee | lymph node | 1.00 | infobox |
| CD74 | Bgee | right lung | 1.00 | infobox |
| CD74 | Bgee | gallbladder | 1.00 | infobox |
| CD74 | Bgee | upper lobe of left lung | 1.00 | infobox |
| CD74 | Bgee | lower lobe of lung | 1.00 | infobox |
| CD74 | Bgee | mucosa of ileum | 1.00 | infobox |
| CD74 | Bgee | jejunum | 1.00 | infobox |
| CD74 | Bgee | thymus | 1.00 | infobox |
| CD74 | Bgee | ileum | 1.00 | infobox |
| CD74 | Bgee | zone of skin | 1.00 | infobox |
| CD74 | Bgee | colon | 1.00 | infobox |
| CD74 | Bgee | lip | 1.00 | infobox |
| CD74 | Bgee | uterus | 1.00 | infobox |
| CD74 | Bgee | adrenal gland | 1.00 | infobox |
| CD74 | Bgee | white adipose tissue | 1.00 | infobox |
| CD74 | BioGPS | More reference expression data | 1.00 | infobox |
| CD74 | Chr. | Chromosome 5 (human) | 1.00 | infobox |
| CD74 | Chr. | Chromosome 18 (mouse) | 1.00 | infobox |
| CD74 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| CD74 | End | 150,412,969 bp | 1.00 | infobox |
| CD74 | End | 60,945,724 bp | 1.00 | infobox |
| CD74 | Ensembl | ENSG00000019582 | 1.00 | infobox |
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