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Runt-related transcription factor 2 (RUNX2) also known as core-binding factor subunit alpha-1 (CBF-alpha-1) is a protein that in humans is encoded by the RUNX2 gene. RUNX2 is a key transcription factor associated with osteoblast differentiation.
Measurement, Function & Interactions
Explore the main themes, entities and connections around RUNX2. Start with the topic map, then use the sections below for research and deeper semantic analysis.
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cell cycle osteoblast transcription protein proliferation differentiation levels also osteoblasts factor gene bp activity chr human band well g1 osteosarcoma
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| RUNX2 | Aliases | RUNX2, AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA, runt related transcription factor 2, Runx2 mRNA, RUNX family transcription factor 2 | 1.00 | infobox |
| RUNX2 | Band | 6p21.1 | 1.00 | infobox |
| RUNX2 | Band | 17 B3|17 21.33 cM | 1.00 | infobox |
| RUNX2 | Bgee | tibia | 1.00 | infobox |
| RUNX2 | Bgee | mucosa of paranasal sinus | 1.00 | infobox |
| RUNX2 | Bgee | trabecular bone | 1.00 | infobox |
| RUNX2 | Bgee | parotid gland | 1.00 | infobox |
| RUNX2 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| RUNX2 | Bgee | testicle | 1.00 | infobox |
| RUNX2 | Bgee | mucosa of nose | 1.00 | infobox |
| RUNX2 | Bgee | cartilage tissue | 1.00 | infobox |
| RUNX2 | Bgee | amniotic fluid | 1.00 | infobox |
| RUNX2 | Bgee | blood | 1.00 | infobox |
| RUNX2 | Bgee | facial skeleton | 1.00 | infobox |
| RUNX2 | Bgee | upper jaw | 1.00 | infobox |
| RUNX2 | Bgee | long bone | 1.00 | infobox |
| RUNX2 | Bgee | cartilage of bone | 1.00 | infobox |
| RUNX2 | Bgee | bones of free part of lower limb | 1.00 | infobox |
| RUNX2 | Bgee | Dermatocranium | 1.00 | infobox |
| RUNX2 | Bgee | membranous bone | 1.00 | infobox |
| RUNX2 | Bgee | body of femur | 1.00 | infobox |
| RUNX2 | Bgee | calvaria | 1.00 | infobox |
| RUNX2 | Bgee | maxilla | 1.00 | infobox |
| RUNX2 | BioGPS | More reference expression data | 1.00 | infobox |
| RUNX2 | Chr. | Chromosome 6 (human) | 1.00 | infobox |
| RUNX2 | Chr. | Chromosome 17 (mouse) | 1.00 | infobox |
| RUNX2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| RUNX2 | End | 45,664,349 bp | 1.00 | infobox |
| RUNX2 | End | 45,125,684 bp | 1.00 | infobox |
| RUNX2 | Ensembl | ENSG00000124813 | 1.00 | infobox |
These clusters group vocabulary that occurs around closely connected concepts in the source material.
Bridges can reveal useful research angles that are easy to miss in a flat list of related terms.