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CASS4

Cas scaffolding protein family member 4 is a protein that in humans is encoded by the CASS4 gene.

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Aliases
CASS4, C20orf32, CAS4, HEFL, HEPL, Cas scaffolding protein family member 4, Cas scaffold protein family member 4
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CRE
Band
20q13.31 · 2|2 H3
Bgee
upper lobe of left lung · blood · right lung · granulocyte · appendix
BioGPS
n/a
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

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Overview

History and discovery

Gene

Protein family

Structure

Function

Disease association

Clinical significance

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Map overview Semantic statistics

CASS4

Nodes60
Edges59
Triples217
Avg. degree1.97
Density0.033333
Components1

How this topic connects Entity context

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CASS4

Top relations

related to Gene · 34
CASS4 → Areb6, C/EBP, C/EBPα, C20orf32, CHOP-10, Cumulatively, E-box, Ensembl, ENSG00000087589, Entrez Gene, GRChB38p2, HEF-like, HEF1-Efs-p130Cas-like, HEFL, HEPL, HGNC, HGNC-approved, In, LCR-F1, MAX1
related to Structure · 27
CASS4 → All CAS, Also, Although, Amino, BCAR1, Carboxy-terminal, CAS, EFS, FAK, FAK C-terminus, FAT, FAT-like, For, Further, In, Isoform, It, N-terminal, NEDD9, SH2
Bgee · 17
CASS4 → appendix, blood, bone marrow, buccal mucosa cell, embryo, epiblast, gallbladder, granulocyte, left lung lobe, mesenteric lymph nodes, monocyte, right lung, right lung lobe, sciatic nerve, spleen, testicle, upper lobe of left lung
RNA expression pattern · 17
CASS4 → appendix, blood, bone marrow, buccal mucosa cell, embryo, epiblast, gallbladder, granulocyte, left lung lobe, mesenteric lymph nodes, monocyte, right lung, right lung lobe, sciatic nerve, spleen, testicle, upper lobe of left lung
related to Alzheimer's disease · 14
CASS4 → AD, Alzheimer's, APP, CAS-family, CASS4 SNPs, Given, GWAS, However, In, Several, SNP, T/C, T/G, Two
related to Function · 14
CASS4 → BCAR1, Because, CAS, CRKL, Direct, FAK, SH2, SH3, Singh, Src, The, These, This, Unusually
Gene ontology · 13
CASS4 → actin filament reorganization, cell adhesion, cell junction, cell migration, cytoplasm, cytoskeleton, focal adhesion, plasma membrane, positive regulation of cell migration, positive regulation of protein tyrosine kinase activity, positive regulation of substrate adhesion-dependent cell spreading, protein tyrosine kinase binding, structural constituent of cytoskeleton
related to history · 13
CASS4 → CAS, CAS-related, Crk, EFS, Gene Nomenclature Committee, HEF1-EFS-p130Cas-like, HEPL, HGNC, HUGO, Human Genome Organization, NEDD9/HEF1, Singh, The
related to Cancer · 11
CASS4 → A549, BE1, Changes, H1299, In, LTE, Many CAS, Miao, NSCLC, These, TNM
related to Protein family · 9
CASS4 → BCAR1, CAS, Drosophila, EFS, Evolutionary, In, NEDD9/HEF1, Singh, There

Important terminology Word statistics

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Important terminology

family cas protein gene human may domain members 20 bp function also p130cas bcar1 member chr band proteins chromosome cancer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CASS4AliasesCASS4, C20orf32, CAS4, HEFL, HEPL, Cas scaffolding protein family member 4, Cas scaffold protein family member 41.00infobox
CASS4Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2CRE1.00infobox
CASS4Band20q13.311.00infobox
CASS4Band2|2 H31.00infobox
CASS4Bgeeupper lobe of left lung1.00infobox
CASS4Bgeeblood1.00infobox
CASS4Bgeeright lung1.00infobox
CASS4Bgeegranulocyte1.00infobox
CASS4Bgeeappendix1.00infobox
CASS4Bgeemonocyte1.00infobox
CASS4Bgeetesticle1.00infobox
CASS4Bgeebuccal mucosa cell1.00infobox
CASS4Bgeegallbladder1.00infobox
CASS4Bgeespleen1.00infobox
CASS4Bgeeleft lung lobe1.00infobox
CASS4Bgeeembryo1.00infobox
CASS4Bgeebone marrow1.00infobox
CASS4Bgeeright lung lobe1.00infobox
CASS4Bgeemesenteric lymph nodes1.00infobox
CASS4Bgeesciatic nerve1.00infobox
CASS4Bgeeepiblast1.00infobox
CASS4BioGPSn/a1.00infobox
CASS4Chr.Chromosome 20 (human)1.00infobox
CASS4Chr.Chromosome 2 (mouse)1.00infobox
CASS4DatabasesNCBI: entry; OMA: entry1.00infobox
CASS4End56,460,387 bp1.00infobox
CASS4End172,275,677 bp1.00infobox
CASS4EnsemblENSG000000875891.00infobox
CASS4Entrez570911.00infobox
CASS4External IDsMGI: 2444482; GeneCards: CASS41.00infobox

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