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BMPR1A: Function, Ligands & Diseases

The bone morphogenetic protein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 292).

Language: English [EN]
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BMPR1A topic overview

The analysis highlights Function, Ligands and Diseases as prominent areas in the source structure around BMPR1A.

Related topics
35
Source areas
5
Connected nodes
40
Extracted relationships
196
Concept neighborhoods
10
Bridge connections
40

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 15 topics
Ligands · 9 topics
Diseases · 5 topics
Interactions · 3 topics
Overview · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.30
Aliases
BMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5, bone morphogenetic protein receptor type 1A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3QB4, 1ES7, 1REW, 2GOO, 2H62, 2H64, 2K3G, 2QJ9, 2QJA, 2QJB, 3NH7
Band
10q23.2 · 14 B|14 20.81 cM
Bgee
secondary oocyte · Achilles tendon · saphenous vein · parotid gland · tail of epididymis
BioGPS
More reference expression data

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Ligands

Diseases

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BMPR1A connects Entity context

The extracted context around BMPR1A shows recurring relationship patterns in the source. For example, BMPR1A → anterior/posterior pattern specification, ATP binding, BMP receptor activity, BMP signaling pathway, BMP signaling pathway involved in heart development, cardiac conduction system development, cardiac right ventricle morphogenesis, cartilage development, caveola, cell differentiation, cell surface, cellular response to BMP stimulus, chondrocyte differentiation, dendrite, development of the heart, developmental growth, DNA-binding transcription factor activity, RNA polymerase II-specific, dorsal aorta morphogenesis, dorsal/ventral axis specification, dorsal/ventral pattern formation Another extracted example is BMPR1A → Achilles tendon, aortic valve, ascending aorta, biceps brachii, calvaria, efferent ductule, epithelium of lens, genital tubercle, iris, parotid gland, popliteal artery, saphenous vein, secondary oocyte, seminal vesicula, tail of epididymis, tibial arteries, urethra, vas deferens, vestibular membrane of cochlear duct, vestibular sensory epithelium. Use these groups to spot repeated connection types before inspecting the individual relationships.

BMPR1A

Top relations

Gene ontology · 101
BMPR1A → anterior/posterior pattern specification, ATP binding, BMP receptor activity, BMP signaling pathway, BMP signaling pathway involved in heart development, cardiac conduction system development, cardiac right ventricle morphogenesis, cartilage development, caveola, cell differentiation, cell surface, cellular response to BMP stimulus, chondrocyte differentiation, dendrite, development of the heart, developmental growth, DNA-binding transcription factor activity, RNA polymerase II-specific, dorsal aorta morphogenesis, dorsal/ventral axis specification, dorsal/ventral pattern formation
Bgee · 20
BMPR1A → Achilles tendon, aortic valve, ascending aorta, biceps brachii, calvaria, efferent ductule, epithelium of lens, genital tubercle, iris, parotid gland, popliteal artery, saphenous vein, secondary oocyte, seminal vesicula, tail of epididymis, tibial arteries, urethra, vas deferens, vestibular membrane of cochlear duct, vestibular sensory epithelium
RNA expression pattern · 20
BMPR1A → Achilles tendon, aortic valve, ascending aorta, biceps brachii, calvaria, efferent ductule, epithelium of lens, genital tubercle, iris, parotid gland, popliteal artery, saphenous vein, secondary oocyte, seminal vesicula, tail of epididymis, tibial arteries, urethra, vas deferens, vestibular membrane of cochlear duct, vestibular sensory epithelium
related to Function · 17
BMPR1A → ACVR1, ACVR2, BMP, BMP's, BMPR1B, BMPR2, II, In, It, Signals, TGF, TGF-betas, The, These, Type II, Using, WNT
related to External links · 7
BMPR1A → GeneReviews/NCBI/NIH/UW, Human BMPR1A, Juvenile Polyposis SyndromeBMPR1A, Medicine Medical Subject Headings, MeSH, National Library, UCSC Genome Browser
related to Diseases · 3
BMPR1A → Cowden's, PTEN, SMAD4
Band · 2
BMPR1A → 10q23.2, 14 B|14 20.81 cM
Chr. · 2
BMPR1A → Chromosome 10 (human), Chromosome 14 (mouse)
End · 2
BMPR1A → 34,225,298 bp, 86,932,825 bp
related to Interactions · 2
BMPR1A → BMP2, SF3B4

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

human bp type gene chr protein band receptor location receptors bone chromosome 10 also external ii morphogenetic differentiation ligands mouse

BMPR1A relationships Subject–Predicate–Object triples

TTTA extracted 196 structured relationships around BMPR1A. Examples in this analysis include BMPR1A → 2.7.11.30 → ↗ and BMPR1A → Aliases → BMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5, bone morphogenetic protein receptor type 1A. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
BMPR1A2.7.11.301.00infobox
BMPR1AAliasesBMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5, bone morphogenetic protein receptor type 1A1.00infobox
BMPR1AAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3QB4, 1ES7, 1REW, 2GOO, 2H62, 2H64, 2K3G, 2QJ9, 2QJA, 2QJB, 3NH71.00infobox
BMPR1ABand10q23.21.00infobox
BMPR1ABand14 B|14 20.81 cM1.00infobox
BMPR1ABgeesecondary oocyte1.00infobox
BMPR1ABgeeAchilles tendon1.00infobox
BMPR1ABgeesaphenous vein1.00infobox
BMPR1ABgeeparotid gland1.00infobox
BMPR1ABgeetail of epididymis1.00infobox
BMPR1ABgeebiceps brachii1.00infobox
BMPR1ABgeeseminal vesicula1.00infobox
BMPR1ABgeepopliteal artery1.00infobox
BMPR1ABgeetibial arteries1.00infobox
BMPR1ABgeeurethra1.00infobox
BMPR1ABgeeascending aorta1.00infobox
BMPR1ABgeeaortic valve1.00infobox
BMPR1ABgeevas deferens1.00infobox
BMPR1ABgeevestibular sensory epithelium1.00infobox
BMPR1ABgeeefferent ductule1.00infobox
BMPR1ABgeegenital tubercle1.00infobox
BMPR1ABgeecalvaria1.00infobox
BMPR1ABgeeepithelium of lens1.00infobox
BMPR1ABgeeiris1.00infobox
BMPR1ABgeevestibular membrane of cochlear duct1.00infobox
BMPR1ABioGPSMore reference expression data1.00infobox
BMPR1AChr.Chromosome 10 (human)1.00infobox
BMPR1AChr.Chromosome 14 (mouse)1.00infobox
BMPR1ADatabasesNCBI: entry; OMA: entry1.00infobox
BMPR1AEnd86,932,825 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BMPR1A bring nearby vocabulary together. In this analysis, examples include Protein, Receptor and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • BMPR1A
    • Protein
    • Receptor
    • Gene
    • Location
    • Human
    • Bone
    • Differentiation
    • Morphogenetic
    • Role
    • Type
    • Activity
    • Cd292
  • bmpr1a
    • Protein
    • Receptor
    • Gene
    • Location
    • Human
    • Bone
    • Differentiation
    • Morphogenetic
    • Role
    • Type
    • Activity
    • Cd292
  • protein
    • Receptor
    • Activity
    • External
    • Function
    • Search
    • Type
    • Human
    • Chromosome
    • Bp
    • Chr
    • Location
    • Cd292
  • gene
    • Location
    • Morphogenetic
    • Human
    • Chromosome
    • Protein
    • Receptor
    • Bp
    • Chr
    • Type
    • Activity
    • End
    • External
  • function
    • Activity
    • External
    • Search
    • Morphogenetic
    • Chromosome
    • Protein
    • Receptor
    • Bp
    • Chr
    • Gene
    • Location
    • Type
  • cell differentiation
    • Differentiation
    • Signaling
    • End
    • External
    • Function
    • Mouse
    • Search
    • Serine
    • Threonine
    • Formation
    • Ii
    • Morphogenetic
  • cluster of differentiation
    • End
    • External
    • Function
    • Mouse
    • Search
    • Serine
    • Threonine
    • Formation
    • Ii
    • Morphogenetic
    • Role
    • Signaling
  • ligands
    • Type
    • Receptors
    • Search
    • Ii
    • Morphogenetic
    • Signaling
    • Protein
    • Receptor
    • Location
    • Human

Connections between topic areas Semantic bridges

For BMPR1A, one of the stronger structural bridges in this analysis connects BMPR1A with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
BMPR1AFunction · splits 25 ⟂ 16
BMPR1ALigands · splits 31 ⟂ 10
BMPR1ADiseases · splits 35 ⟂ 6
BMPR1AOverview · splits 37 ⟂ 4
BMPR1AInteractions · splits 37 ⟂ 4

Map overview Semantic statistics

BMPR1A

Nodes41
Edges40
Triples196
Avg. degree1.95
Density0.04878
Components1

Source & methodology

TTTA analyzes the structure around BMPR1A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Ligands & Diseases, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BMPR1A · EN edition · Analysis: TopicsToTalkAbout

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