BMPR2

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BMPR2 topic overview

The analysis highlights Oocyte development, Function and Clinical significance as prominent areas in the source structure around BMPR2.

Related topics: 34
Source areas: 4
Connected nodes: 38
Extracted relationships: 200
Concept neighborhoods: 17
Bridge connections: 38

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Oocyte development · 12 topics

Overview · 11 topics

Function · 6 topics

Clinical significance · 5 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.30: ↗
Aliases: BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK, bone morphogenetic protein receptor type 2
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HLQ, 3G2F
Band: 2q33.1-q33.2 · 1|1 C2
Bgee: visceral pleura · lower lobe of lung · tendon of biceps brachii · urethra · lateral nuclear group of thalamus
BioGPS: n/a

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Serine/threonine receptor kinase
Bone morphogenetic proteins
TGF beta superfamily
Ligands Ligand (biochemistry)
Paracrine signaling
Osteogenesis
Cell growth
Cell differentiation
BMP pathway TGF beta signaling pathway
BMP type I receptor Bone morphogenetic protein receptor, type 1
R-SMAD

Function

BMP-2 Bone morphogenetic protein 2
BMP-7
BMP-4
Homodimers Homodimer
Ligand
Equilibrium Chemical equilibrium

Oocyte development

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How BMPR2 connects Entity context

The extracted context around BMPR2 shows recurring relationship patterns in the source. For example, BMPR2 → activin receptor activity, type II, activin receptor signaling pathway, anterior/posterior pattern specification, aortic valve development, apical plasma membrane, artery development, ATP binding, atrial septum morphogenesis, atrioventricular valve morphogenesis, basal plasma membrane, blood vessel remodeling, BMP binding, BMP receptor activity, BMP signaling pathway, brain development, cardiac muscle tissue development, caveola, cell surface, cellular response to BMP stimulus, cellular response to starvation Another extracted example is BMPR2 → carotid body, ciliary body, cumulus cell, epithelium of lens, iris, lateral nuclear group of thalamus, lower lobe of lung, molar, parietal pleura, pineal gland, retinal pigment epithelium, right lung, right lung lobe, skin of hip, skin of thigh, substantia nigra, tail of epididymis, tendon of biceps brachii, urethra, visceral pleura. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

Gene ontology · 94

BMPR2 → activin receptor activity, type II, activin receptor signaling pathway, anterior/posterior pattern specification, aortic valve development, apical plasma membrane, artery development, ATP binding, atrial septum morphogenesis, atrioventricular valve morphogenesis, basal plasma membrane, blood vessel remodeling, BMP binding, BMP receptor activity, BMP signaling pathway, brain development, cardiac muscle tissue development, caveola, cell surface, cellular response to BMP stimulus, cellular response to starvation

Bgee · 20

BMPR2 → carotid body, ciliary body, cumulus cell, epithelium of lens, iris, lateral nuclear group of thalamus, lower lobe of lung, molar, parietal pleura, pineal gland, retinal pigment epithelium, right lung, right lung lobe, skin of hip, skin of thigh, substantia nigra, tail of epididymis, tendon of biceps brachii, urethra, visceral pleura

RNA expression pattern · 20

related to Function · 19

BMPR2 → Binding, BMP, BMP-2, BMP-4, BMP-7, BMPs, II, II TGF, In, In TGF, On, Once, SMAD, TGF-β1, TGFβ, The, They, Type II, Unlike

related to Oocyte development · 12

BMPR2 → BMP15, BMPR1B, BMPR2-mediated, Experimental, FSH, GDF9, However, It, KGN, TGFβR1, There, These

related to Clinical significance · 5

BMPR2 → An, At, It, The, When

related to External links · 4

BMPR2 → Heritable Pulmonary Arterial HypertensionHuman, Heritable Pulmonary Arterial HypertensionOMIM, NCBI/NIH/UW, UCSC Genome Browser

Band · 2

BMPR2 → 1|1 C2, 2q33.1-q33.2

Chr. · 2

BMPR2 → Chromosome 1 (mouse), Chromosome 2 (human)

End · 2

BMPR2 → 202,567,751 bp, 59,918,173 bp

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor type ii gene human bone bp pulmonary signaling protein binding morphogenetic bmp chr band arterial growth ligand chromosome beta

BMPR2 relationships Subject–Predicate–Object triples

TTTA extracted 200 structured relationships around BMPR2. Examples in this analysis include BMPR2 → 2.7.11.30 → ↗ and BMPR2 → Aliases → BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK, bone morphogenetic protein receptor type 2. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
BMPR2	2.7.11.30	↗	1.00	infobox
BMPR2	Aliases	BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK, bone morphogenetic protein receptor type 2	1.00	infobox
BMPR2	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2HLQ, 3G2F	1.00	infobox
BMPR2	Band	2q33.1-q33.2	1.00	infobox
BMPR2	Band	1\|1 C2	1.00	infobox
BMPR2	Bgee	visceral pleura	1.00	infobox
BMPR2	Bgee	lower lobe of lung	1.00	infobox
BMPR2	Bgee	tendon of biceps brachii	1.00	infobox
BMPR2	Bgee	urethra	1.00	infobox
BMPR2	Bgee	lateral nuclear group of thalamus	1.00	infobox
BMPR2	Bgee	parietal pleura	1.00	infobox
BMPR2	Bgee	right lung	1.00	infobox
BMPR2	Bgee	skin of thigh	1.00	infobox
BMPR2	Bgee	skin of hip	1.00	infobox
BMPR2	Bgee	tail of epididymis	1.00	infobox
BMPR2	Bgee	cumulus cell	1.00	infobox
BMPR2	Bgee	ciliary body	1.00	infobox
BMPR2	Bgee	iris	1.00	infobox
BMPR2	Bgee	carotid body	1.00	infobox
BMPR2	Bgee	right lung lobe	1.00	infobox
BMPR2	Bgee	substantia nigra	1.00	infobox
BMPR2	Bgee	molar	1.00	infobox
BMPR2	Bgee	retinal pigment epithelium	1.00	infobox
BMPR2	Bgee	pineal gland	1.00	infobox
BMPR2	Bgee	epithelium of lens	1.00	infobox
BMPR2	BioGPS	n/a	1.00	infobox
BMPR2	Chr.	Chromosome 2 (human)	1.00	infobox
BMPR2	Chr.	Chromosome 1 (mouse)	1.00	infobox
BMPR2	Databases	NCBI: entry; OMA: entry	1.00	infobox
BMPR2	End	202,567,751 bp	1.00	infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around BMPR2 bring nearby vocabulary together. In this analysis, examples include Bone, Protein and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

BMPR2
- Bone
- Protein
- Receptor
- Human
- Gene
- Pulmonary
- Expression
- Morphogenetic
- Arterial
- Factor
- Type
- Hypertension
bmpr2
- Bone
- Protein
- Receptor
- Human
- Gene
- Pulmonary
- Expression
- Morphogenetic
- Arterial
- Factor
- Type
- Hypertension
serine/threonine receptor kinase
- Threonine
- Type
- Binding
- Factor
- Serine
- Bmp
- Mouse
- Growth
- Ligand
- Cell
- Development
- Differentiation
bone morphogenetic proteins
- Morphogenetic
- Protein
- Factor
- Receptor
- Growth
- Human
- Bmpr2
- Development
- Differentiation
- Involved
- Serine
- Threonine
tgf beta superfamily
- Tgf
- Signaling
- Involved
- Ligand
- Receptors
- Binding
- Bone
- Ii
- Mouse
- Cell
- Development
- Differentiation
paracrine signaling
- Pathway
- Binding
- Development
- Tgf
- Bmp
- Mouse
- Type
- Cell
- Differentiation
- Endothelial
- Factor
- Threonine
cell growth
- Differentiation
- Factor
- Involved
- Expression
- Protein
- Endothelial
- Growth
- Cells
- Human
- Morphogenetic
- Mouse
- Receptor
cell differentiation
- Growth
- Differentiation
- Factor
- Involved
- Expression
- Protein
- Human
- Mouse
- Development
- Endothelial
- Functions
- Pathway

Connections between topic areas Semantic bridges

For BMPR2, one of the stronger structural bridges in this analysis connects BMPR2 with Oocyte development. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

BMPR2 — Oocyte development · splits 26 ⟂ 13

BMPR2 — Overview · splits 27 ⟂ 12

BMPR2 — Function · splits 32 ⟂ 7

BMPR2 — Clinical significance · splits 33 ⟂ 6

Map overview Semantic statistics

BMPR2

Nodes39

Edges38

Triples200

Avg. degree1.95

Density0.051282

Components1

Source & methodology

TTTA analyzes the structure around BMPR2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Oocyte development, Function & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — BMPR2 · EN edition · Analysis: TopicsToTalkAbout