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Bone morphogenetic protein 7: Applications, Function & Therapeutic application

Bone morphogenetic protein 7 or BMP7 (also known as osteogenic protein-1 or OP-1) is a protein that in humans is encoded by the BMP7 gene.

Language: English [EN]
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Bone morphogenetic protein 7 topic overview

The analysis highlights Applications, Function and Therapeutic application as prominent areas in the source structure around Bone morphogenetic protein 7.

Related topics
19
Source areas
4
Connected nodes
23
Extracted relationships
173
Concept neighborhoods
8
Bridge connections
23

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 13 topics
Therapeutic application · 3 topics
Overview · 2 topics
Promotion of brown fat · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
BMP7, OP-1, bone morphogenetic protein 7
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U
Band
20q13.31 · 2 H3|2 95.54 cM
Bgee
retinal pigment epithelium · ventricular zone · optic nerve · ganglionic eminence · olfactory bulb
BioGPS
n/a
Chr.
Chromosome 20 (human) · Chromosome 2 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Therapeutic application

Promotion of brown fat

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Bone morphogenetic protein 7 connects Entity context

The extracted context around Bone morphogenetic protein 7 shows recurring relationship patterns in the source. For example, Bone morphogenetic protein 7 → allantois development, anatomical structure formation involved in morphogenesis, animal organ morphogenesis, axon guidance, BMP receptor binding, BMP signaling pathway, branching involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, camera-type eye morphogenesis, cardiac muscle tissue development, cardiac septum morphogenesis, cartilage development, cell development, cell differentiation, cellular response to BMP stimulus, cellular response to hypoxia, chorio-allantoic fusion, collagen-containing extracellular matrix, cytokine activity, dendrite development Another extracted example is Bone morphogenetic protein 7 → allantois, buccal mucosa cell, ganglionic eminence, genital tubercle, left lobe of thyroid gland, lip, molar, mucosa of esophagus, neural fold, neural groove, olfactory bulb, optic nerve, renal corpuscle, retinal pigment epithelium, right lobe of thyroid gland, surface ectoderm, thyroid gland, transitional epithelium of urinary bladder, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.

Bone morphogenetic protein 7

Top relations

Gene ontology · 105
Bone morphogenetic protein 7 → allantois development, anatomical structure formation involved in morphogenesis, animal organ morphogenesis, axon guidance, BMP receptor binding, BMP signaling pathway, branching involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, camera-type eye morphogenesis, cardiac muscle tissue development, cardiac septum morphogenesis, cartilage development, cell development, cell differentiation, cellular response to BMP stimulus, cellular response to hypoxia, chorio-allantoic fusion, collagen-containing extracellular matrix, cytokine activity, dendrite development
Bgee · 19
Bone morphogenetic protein 7 → allantois, buccal mucosa cell, ganglionic eminence, genital tubercle, left lobe of thyroid gland, lip, molar, mucosa of esophagus, neural fold, neural groove, olfactory bulb, optic nerve, renal corpuscle, retinal pigment epithelium, right lobe of thyroid gland, surface ectoderm, thyroid gland, transitional epithelium of urinary bladder, ventricular zone
RNA expression pattern · 19
Bone morphogenetic protein 7 → allantois, buccal mucosa cell, ganglionic eminence, genital tubercle, left lobe of thyroid gland, lip, molar, mucosa of esophagus, neural fold, neural groove, olfactory bulb, optic nerve, renal corpuscle, retinal pigment epithelium, right lobe of thyroid gland, surface ectoderm, thyroid gland, transitional epithelium of urinary bladder, ventricular zone
related to External links · 7
Bone morphogenetic protein 7 → BMP7, Medicine Medical Subject Headings, MeSH, Molecule, National Library, UCSC Genome Browser, Year
Band · 2
Bone morphogenetic protein 7 → 2 H3|2 95.54 cM, 20q13.31
Chr. · 2
Bone morphogenetic protein 7 → Chromosome 2 (mouse), Chromosome 20 (human)
End · 2
Bone morphogenetic protein 7 → 172,782,114 bp, 57,266,641 bp
Aliases · 1
Bone morphogenetic protein 7 → BMP7, OP-1, bone morphogenetic protein 7
Available structures · 1
Bone morphogenetic protein 7 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U
BioGPS · 1
Bone morphogenetic protein 7 → n/a

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bmp7 human bone protein bp gene also chr band fibrosis kidney treatment bmp-7 emt chromosome 20 morphogenetic location development expression

Bone morphogenetic protein 7 relationships Subject–Predicate–Object triples

TTTA extracted 173 structured relationships around Bone morphogenetic protein 7. Examples in this analysis include Bone morphogenetic protein 7 → Aliases → BMP7, OP-1, bone morphogenetic protein 7 and Bone morphogenetic protein 7 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Bone morphogenetic protein 7AliasesBMP7, OP-1, bone morphogenetic protein 71.00infobox
Bone morphogenetic protein 7Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BMP, 1LX5, 1LXI, 1M4U1.00infobox
Bone morphogenetic protein 7Band20q13.311.00infobox
Bone morphogenetic protein 7Band2 H3|2 95.54 cM1.00infobox
Bone morphogenetic protein 7Bgeeretinal pigment epithelium1.00infobox
Bone morphogenetic protein 7Bgeeventricular zone1.00infobox
Bone morphogenetic protein 7Bgeeoptic nerve1.00infobox
Bone morphogenetic protein 7Bgeeganglionic eminence1.00infobox
Bone morphogenetic protein 7Bgeeolfactory bulb1.00infobox
Bone morphogenetic protein 7Bgeethyroid gland1.00infobox
Bone morphogenetic protein 7Bgeeleft lobe of thyroid gland1.00infobox
Bone morphogenetic protein 7Bgeeright lobe of thyroid gland1.00infobox
Bone morphogenetic protein 7Bgeebuccal mucosa cell1.00infobox
Bone morphogenetic protein 7Bgeemucosa of esophagus1.00infobox
Bone morphogenetic protein 7Bgeemolar1.00infobox
Bone morphogenetic protein 7Bgeeallantois1.00infobox
Bone morphogenetic protein 7Bgeelip1.00infobox
Bone morphogenetic protein 7Bgeetransitional epithelium of urinary bladder1.00infobox
Bone morphogenetic protein 7Bgeesurface ectoderm1.00infobox
Bone morphogenetic protein 7Bgeegenital tubercle1.00infobox
Bone morphogenetic protein 7Bgeeneural groove1.00infobox
Bone morphogenetic protein 7Bgeeneural fold1.00infobox
Bone morphogenetic protein 7Bgeerenal corpuscle1.00infobox
Bone morphogenetic protein 7BioGPSn/a1.00infobox
Bone morphogenetic protein 7Chr.Chromosome 20 (human)1.00infobox
Bone morphogenetic protein 7Chr.Chromosome 2 (mouse)1.00infobox
Bone morphogenetic protein 7DatabasesNCBI: entry; OMA: entry1.00infobox
Bone morphogenetic protein 7End57,266,641 bp1.00infobox
Bone morphogenetic protein 7End172,782,114 bp1.00infobox
Bone morphogenetic protein 7EnsemblENSG000001011441.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Bone morphogenetic protein 7 bring nearby vocabulary together. In this analysis, examples include Protein, Morphogenetic and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Bone morphogenetic protein 7
    • Protein
    • Morphogenetic
    • Gene
    • Op-1
    • Expressed
    • Function
    • May
    • Role
    • Bmp7
    • Chromosome
    • Development
    • Location
  • bone morphogenetic protein 7
    • Protein
    • Morphogenetic
    • Op-1
    • Role
    • Gene
    • Expressed
    • External
    • Function
    • Location
    • May
    • Bmp7
    • Chromosome
  • gene
    • Location
    • Chromosome
    • Human
    • Bp
    • Chr
    • Mouse
    • Op-1
    • Protein
    • End
    • Function
    • Band
    • Development
  • bone morphogenetic protein
    • Protein
    • Morphogenetic
    • Op-1
    • Role
    • Gene
    • Expressed
    • External
    • Function
    • Location
    • May
    • Bmp7
    • Chromosome
  • bone graft
    • Protein
    • Morphogenetic
    • Gene
    • Op-1
    • Function
    • May
    • Role
    • Bmp7
    • Chromosome
    • Development
    • Location
    • Bp
  • function
    • Cell
    • Epithelial
    • Chromosome
    • Development
    • Location
    • Bp
    • Chr
    • External
    • Gene
    • Protein
    • Human
    • Mouse
  • protein
    • Role
    • Expressed
    • Location
    • Human
    • Mouse
    • Cell
    • End
    • Epithelial
    • May
    • Monocyte
    • Nephron
    • Tissue
  • promotion of brown fat
    • External
    • Op-1
    • Function
    • Role
    • Chromosome
    • Development
    • Location
    • Morphogenetic
    • Bp
    • Chr
    • Gene
    • Protein

Connections between topic areas Semantic bridges

For Bone morphogenetic protein 7, one of the stronger structural bridges in this analysis connects Bone morphogenetic protein 7 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Bone morphogenetic protein 7Function · splits 10 ⟂ 14
Bone morphogenetic protein 7Therapeutic application · splits 20 ⟂ 4
Bone morphogenetic protein 7Overview · splits 21 ⟂ 3

Map overview Semantic statistics

Bone morphogenetic protein 7

Nodes24
Edges23
Triples173
Avg. degree1.92
Density0.083333
Components1

Source & methodology

TTTA analyzes the structure around Bone morphogenetic protein 7 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Applications, Function & Therapeutic application, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Bone morphogenetic protein 7 · EN edition · Analysis: TopicsToTalkAbout

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